IBS - Irritable Bowel Syndrome

Gastroenterology
2
Pipeline Programs
3
Companies
3
Clinical Trials
1
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
0
0
0
2
Early DiscoveryClinical DevelopmentMarket

On Market (1)

Approved therapies currently available

U
RIFAXIMINApproved
rifaximin
Unknown Company
oral

Competitive Landscape

3 companies ranked by most advanced pipeline stage

City Therapeutics
City TherapeuticsMA - Cambridge
1 program
1
RifaximinPhase 41 trial
Active Trials
NCT04074421UnknownEst. Dec 2022
Precision BioSciences
1 program
QiMeiYan ProbioticsN/A1 trial
Active Trials
NCT05900752Completed140Est. Jul 2023
Bioiberica
BioibericaSpain - Barcelona
1 program
turmericN/A1 trial
Active Trials
NCT05016596CompletedEst. Apr 2022

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
City TherapeuticsRifaximin
Precision BioSciencesQiMeiYan Probiotics
Bioibericaturmeric

Clinical Trials (3)

Total enrollment: 140 patients across 3 trials

NCT04074421City TherapeuticsRifaximin

Effects of Continuous Treatment With Rifaximin and Probiotics on the Gut Microbiota of Patients With IBS-D

Start: May 2020Est. completion: Dec 2022
Phase 4Unknown
NCT05900752Precision BioSciencesQiMeiYan Probiotics

A Multi-Strain Probiotic Reduces the Frequency of Diarrhea in IBS-D Patients

Start: Jun 2023Est. completion: Jul 2023140 patients
N/ACompleted
NCT05016596Bioibericaturmeric

Postprandial Lipids in IBS and Nutritional Treatment

Start: Nov 2021Est. completion: Apr 2022
N/ACompleted

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Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

3 companies competing in this space

Related Indications

Hepatic Impairment(79)Gastroesophageal Reflux Disease(37)Irritable Bowel Syndrome(29)Gastroesophageal Reflux(27)Liver Transplantation(24)Celiac Disease(23)Hepatic Insufficiency(22)Liver Cirrhosis(22)Gastroesophageal Reflux Disease (GERD)(14)Hepatic Encephalopathy(12)