Hemodialysis Patients

Nephrology
3
Pipeline Programs
3
Companies
4
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
0
0
3
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

3 companies ranked by most advanced pipeline stage

CP
Chugai PharmaJapan - Tokyo
3 programs
3
R744Phase 31 trial
R744Phase 31 trial
R744Phase 31 trial
Active Trials
NCT00433693Completed50Est. Oct 2008
NCT00491868Completed134Est. Aug 2008
NCT00433888Completed179Est. Oct 2008
Aura Biosciences
Aura BiosciencesMA - Boston
1 program
ProteolysisN/A
Rein Therapeutics
1 program
ProteolysisN/A1 trial
Active Trials
NCT01114789UnknownEst. Mar 2013

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
Chugai PharmaR744
Chugai PharmaR744
Chugai PharmaR744
Rein TherapeuticsProteolysis

Clinical Trials (4)

Total enrollment: 363 patients across 4 trials

NCT00491868Chugai PharmaR744

Clinical Study of R744 to Hemodialysis Patients

Start: Jun 2007Est. completion: Aug 2008134 patients
Phase 3Completed
NCT00433693Chugai PharmaR744

Correction Study of R744 in Renal Anemia Patients on Hemodialysis

Start: Feb 2007Est. completion: Oct 200850 patients
Phase 3Completed
NCT00433888Chugai PharmaR744

Switch and Maintenance Study of Intravenous Injections of R744 to Hemodialysis Patients (Phase Ⅲ Study)

Start: Jan 2007Est. completion: Oct 2008179 patients
Phase 3Completed
NCT01114789Rein TherapeuticsProteolysis

Impact on the Proteolysis of Obesity in Dialysis

Start: Jan 2011Est. completion: Mar 2013
N/AUnknown

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Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

3 late-stage (Phase 3) programs — potential near-term approvals
3 companies competing in this space

Related Indications

Chronic Kidney Disease(86)Renal Impairment(67)End Stage Renal Disease(56)Kidney Transplantation(49)Renal Insufficiency(27)Chronic Kidney Diseases(25)Kidney Transplant(19)Diabetic Nephropathies(18)Kidney Diseases(17)Kidney Transplant Rejection(16)