Glioblastoma
Pipeline by Development Stage
Drug Modality Breakdown
On Market (1)
Approved therapies currently available
Competitive Landscape
39 companies ranked by most advanced pipeline stage
+9 more companies
Trial Timeline
Clinical trial activity over time
Showing 15 of 50 trials with date data
Clinical Trials (50)
Total enrollment: 3,373 patients across 50 trials
Beginning Radiation Immediately With GammaTile at GBM Excision Versus Standard of Care
Tofacitinib in Recurrent GBM Patients
Phase III Study of Rindopepimut/GM-CSF in Patients With Newly Diagnosed Glioblastoma
Clinical Trial to Assess the Efficacy and Safety of 'Immuncell-LC' With Temozolomide in Newly Diagnosed Glioblastoma of Korea
Phase III Trial of Primary Radio- or Chemotherapy in Malignant Astrocytoma of the Elderly
Study of IV Edotecarin Vs Temozolomide or Carmustine (BCNU) or Lomustine (CCNU) in Patients With Glioblastoma Multiforme
N-803 and PD-L1 t-haNK Combined With Bevacizumab for Recurrent or Progressive Glioblastoma
A Study With L19TNF in Combination With Lomustine in Patients With Glioblastoma at Progression or Recurrence
ARISTOCRAT: Blinded Trial of Temozolomide +/- Cannabinoids
Paxalisib With a High Fat, Low Carb Diet and Metformin for Glioblastoma
DC Migration Study to Evaluate TReg Depletion In GBM Patients With and Without Varlilumab
Ferumoxytol MRI in Assessing Response to Pembrolizumab in Patients With Glioblastoma
Oral ONC201 in Adult Recurrent Glioblastoma
Study Evaluating the Efficacy and Safety of Selinexor (KPT-330) in Participants With Recurrent Gliomas
Phase 2 Study to Investigate the Efficacy and Safety of Aldoxorubicin in Subjects With Glioblastoma
Imaging Trial With I-124-CLR1404 in Patients With Newly Diagnosed or Recurrent Glioblastoma
BIBF 1120 for Recurrent High-Grade Gliomas
A Study of Rindopepimut/GM-CSF in Patients With Relapsed EGFRvIII-Positive Glioblastoma
Comparison of Two Dosing Regimens of Temozolomide in Patients With Progressive or Recurrent Glioblastoma
Cilengitide, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma and Unmethylated Gene Promoter Status
Avastin in Combination With Temozolomide for Unresectable or Multifocal GBMs and Gliosarcomas
Ph. II Treatment of Adults w Primary Malignant Glioma w Irinotecan + Temozolomide
A Study of the Safety and Efficacy of Tarceva in Patients With First Relapse of Grade IV Glioma (Glioblastoma Multiforme)
A Study to Evaluate Safety and Efficacy of L19TNF Plus Lomustine in Patients With Glioblastoma at First Progression
Safety and Efficacy of L19TNF Plus Temozolomide Chemoradiotherapy in Patients With Newly Diagnosed Glioblastoma
A Phase 1-2 Study of ST101 in Patients With Advanced Solid Tumors
Study to Evaluate Ibudilast and TMZ Combo Treatment in Newly Diagnosed and Recurrent Glioblastoma
Safety and Efficacy of the ONCOlytic VIRus Armed for Local Chemotherapy, TG6002/5-FC, in Recurrent Glioblastoma Patients
Study of CCNU (Lomustine) Plus Dasatinib in Recurrent Glioblastoma (GBM)
A Surgical Window of Opportunity Clinical Trial of Troriluzole in Recurrent IDH Wild-Type Glioblastoma
Safety and Tolerability of CVGBM in Adults With Newly Diagnosed MGMT-Unmethylated Glioblastoma or Astrocytoma
RMC-5552 Monotherapy in Adult Subjects With Recurrent Glioblastoma
CART-EGFR-IL13Ra2 in EGFR Amplified Recurrent GBM
A Study to Determine How BI 907828 (Brigimadlin) is Taken up in the Tumor (Phase 0) and to Determine the Highest Dose of BI 907828 (Brigimadlin) That Could be Tolerated (Phase 1a) in Combination With Radiation Therapy in People With a Brain Tumor Called Glioblastoma
Safety and Efficacy of Different Administration Sequences of L19TNF With Lomustine in Glioblastoma at First Progression
AZD1390 in Recurrent and Newly Diagnosed WHO Grade 4 Glioma Patients
A Dose Finding Study of [177Lu]Lu-DOTA-TATE in Newly Diagnosed Glioblastoma in Combination With Standard of Care and in Recurrent Glioblastoma as a Single Agent.
AB154 Combined With AB122 for Recurrent Glioblastoma
Tumor Treating Fields With Chemoradiation in Newly Diagnosed GBM
Neuro/Sacituzumab Govitecan/Breast Brain Metastasis/Glioblastoma/Ph 0
Pembrolizumab and Vorinostat Combined With Temozolomide for Newly Diagnosed Glioblastoma
HMPL-813 in Treating Patients With Glioblastoma
Microtubule-Targeted Agent BAL101553 and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma
RRx-001 + Radiation + Temozolomide In Newly Diagnosed Glioblastoma and Anaplastic Gliomas
Anti-LAG-3 Alone & in Combination w/ Nivolumab Treating Patients w/ Recurrent GBM (Anti-CD137 Arm Closed 10/16/18)
Preoperative Ceritinib (LDK378) in Glioblastoma Multiforme and CNS Metastasis
GAPVAC Phase I Trial in Newly Diagnosed Glioblastoma Patients
A Phase 0 Study of AZD1775 in Recurrent GBM Patients
Peptide-based Glioma Vaccine IMA950 in Patients With Glioblastoma
Cilengitide Together With Radiochemotherapy in Patients With Locally Advanced Non Small Cell Lung Cancer