Philogen
Italy - Monteriggioni
BiotechnologyFocus: Small Molecules, Biologics, ADCs
Philogen is a life sciences company focused on Small Molecules, Biologics, ADCs.
OncologyUnknownImmunology
Funding Stage
PUBLIC
Open Jobs
12
Pipeline & Clinical Trials
IL12-L19L19
Advanced Solid TumorClinical Trials (1)
NCT04471987Safety and Early Signs of Efficacy of IL12-L19L19.
Phase 1Phase 1
Clinical Trials (1)
NCT02076620L19TNFα in Combination With Doxorubicin in Patients With Advanced Solid Tumours
Phase 1F8IL10
Rheumatoid ArthritisClinical Trials (1)
NCT02076659Combination Therapy of F8IL10 and Methotrexate in Rheumatoid Arthritis Patients
Phase 1Phase 1
Phase 1
Clinical Trials (1)
NCT02957032A Study of the Tumor-targeting Human F16IL2 Monoclonal Antibody-cytokine Fusion Protein in Combination With Very Low-dose Cytarabine in Patients With AML Relapse After Allogeneic Hematopoietic Stem Cell Transplantation
Phase 1L19IL2 monoclonal antibody-cytokine fusion protein in combination with gemcitabine
Pancreatic Cancer Patients Diagnosed With Locally Advanced or Metastatic Pancreatic Cancer Not Amenable to Curative Surgical ResectionClinical Trials (1)
NCT01198522Combination Therapy of L19IL2 and Gemcitabine in Advanced Pancreatic Cancer Patients
Phase 1Phase 1
Clinical Trials (1)
NCT07245992A Study of F8IL10 Intra-articular Treatment in Rheumatoid Arthritis
Phase 1L19TNF
Soft Tissue SarcomaClinical Trials (1)
NCT04032964Dose Finding Study of L19TNF and Doxorubicin in Patients With STS
Phase 1F8IL10
Rheumatoid ArthritisClinical Trials (1)
NCT05622175Safety and Preliminary Signs of Efficacy of F8IL10 for Intra-articular Treatment
Phase 1131I-L19SIP Radioimmunotherapy
Non Small Cell Lung CancerClinical Trials (1)
NCT01124812131I-L19SIP Radioimmunotherapy Combined With Radiochemotherapy in Patients With Locally-advanced Non Small Cell Lung Cancer (NSCLC)
Phase 1[68Ga]Ga-OncoFAP administration
Breast CancerClinical Trials (1)
NCT05784597A Study to Evaluate the Safety and Dosimetry of 68Ga-labelled OncoFAP Derivatives in Solid Tumors
Phase 1Onfekafusp alfa
GlioblastomaClinical Trials (1)
NCT05304663Safety and Efficacy of Different Administration Sequences of L19TNF With Lomustine in Glioblastoma at First Progression
Phase 1Isolated inferior limb perfusion
Patients With Intransit Stage III/IV MelanomaClinical Trials (1)
NCT01213732Phase 1 Dose-finding Study of L19TNFα Plus Melphalan Using Isolated Inferior Limb Perfusion (ILP) in Subjects With Intransit Stage III/IV Melanoma
Phase 1[177Lu]Lu-OncoFAP-23
FAPClinical Trials (1)
NCT06640413A Study to Evaluate the Safety and Preliminary Signs of Efficacy of [177Lu]Lu-OncoFAP-23 Alone or in Combination With L19-IL2 as a Treatment of Metastatic FAP-positive Solid Tumors
Phase 1[68Ga]Ga-OncoACP3
Prostate CancerClinical Trials (1)
NCT06840535A Study to Evaluate the Safety and Dosimetry of 68Ga-OncoACP3 in Patients With Prostate Cancer
Phase 1[68Ga]Ga-OncoCAIX
Clear Cell Renal Cell Carcinoma (ccRCC)Clinical Trials (1)
NCT06840548A Study to Evaluate the Safety and Dosimetry of 68Ga-OncoCAIX in Patients With CAIX-positive Cancer
Phase 1L19IL2 - Ph I
Metastatic Melanoma Stage IVClinical Trials (1)
NCT02076646A Phase I/II Dose Escalation Study of the Tumor-targeting Human L19-IL2 Monoclonal Antibody-cytokine Fusion Protein in Combination With Dacarbazine for Patients With Metastatic Melanoma
Phase 1/2L19TNF
Glioma of BrainClinical Trials (1)
NCT03779230Safety and Efficacy of L19TNF in Patients With Isocitrate Dehydrogenase (IDH) Wildtype WHO Grade III / IV Glioma at First Relapse
Phase 1/2L19TNF
GlioblastomaClinical Trials (1)
NCT04573192A Study to Evaluate Safety and Efficacy of L19TNF Plus Lomustine in Patients With Glioblastoma at First Progression
Phase 1/2L19TNFa
Solid TumorsClinical Trials (1)
NCT01253837L19TNFα in Patients With Advanced Solid Tumors
Phase 1/2L19-IL2 - Ph I
Diffuse Large B-cell Lymphoma (DLBCL)Clinical Trials (1)
NCT02957019A Phase I/II Study of the Tumor-targeting Human L19-IL2 Monoclonal Antibody-cytokine Fusion Protein in Combination With Rituximab in Relapsed or Refractory Diffuse Large B-cell Lymphoma (DLBCL)
Phase 1/2F16IL2 in combination with doxorubicin
Advanced Solid TumorClinical Trials (1)
NCT01131364Combination Therapy of F16IL2 and Doxorubicin in Solid Tumour Patients
Phase 1/2131I-L19SIP Radioimmunotherapy
Patients With CancerClinical Trials (1)
NCT01242943Radioimmunotherapy With 131I-L19SIP in Patients With Cancer
Phase 1/2Phase 1/2
Clinical Trials (1)
NCT05468294F16IL2 in Combination With Nivolumab in Patients With Non-small Cell Lung Cancer
Phase 1/2131I-F16SIP Radioimmunotherapy
CancerClinical Trials (1)
NCT01240720A Dose Finding and Efficacy Study of the Tumour Targeting Human 131I-F16SIP Monoclonal Antibody in Patients With Cancer
Phase 1/2L19IL2
Advanced Solid TumoursClinical Trials (1)
NCT01058538A Dose Finding Pharmacokinetic Study of the Tumour-targeting Human L19IL2 Monoclonal Antibody-Cytokine Fusion Protein in Patients With Advanced Solid Tumours
Phase 1/2F16IL2 in combination with paclitaxel
Solid TumorClinical Trials (1)
NCT01134250Combination Therapy of F16IL2 and Paclitaxel in Solid Tumour Patients
Phase 1/2Onfekafusp alfa
GlioblastomaClinical Trials (1)
NCT04443010Safety and Efficacy of L19TNF Plus Temozolomide Chemoradiotherapy in Patients With Newly Diagnosed Glioblastoma
Phase 1/2F8IL10
Rheumatoid ArthritisClinical Trials (1)
NCT02270632A Randomized, Placebo-controlled Phase II Clinical Trial to Evaluate the Safety and Efficacy of F8IL10 (Dekavil) in Patients With Active RA Receiving MTX
Phase 2Doxorubicin
LeiomyosarcomaClinical Trials (1)
NCT03420014Treatment of Metastatic Soft Tissue Sarcoma (STS) Patients (FIBROSARC USA)
Phase 2Arm A: F16IL2 in combination with paclitaxel
Merkel Cell Carcinoma131I-L19SIP Radioimmunotherapy
Brain Metastases From Solid TumorsClinical Trials (1)
NCT01125085131I-L19SIP Radioimmunotherapy (RIT) in Combination With External Beam Radiation in Patients With Multiple Brain Metastases From Solid Tumors
Phase 2Phase 2
Clinical Trials (1)
NCT07227350L19IL2 or L19TNF or L19IL2/TNF in Patients With Basal Cell Carcinoma (BCC)
Phase 2L19TNF
GlioblastomaClinical Trials (1)
NCT06336291A Study With L19TNF in Combination With Lomustine in Patients With Glioblastoma at Progression or Recurrence
Phase 2L19IL2/L19TNF
BCC - Basal Cell CarcinomaClinical Trials (1)
NCT05329792L19IL2/L19TNF in Skin Cancer Patients
Phase 2L19IL2 +L19TNF
Carcinoma, Basal CellClinical Trials (1)
NCT04362722Intratumoral Administration of Daromun in Non-melanoma Skin Cancer Patients
Phase 2L19IL2+L19TNF
Malignant Melanoma, SkinClinical Trials (1)
NCT02076633Intratumoral Administration of L19IL2/L19TNF
Phase 2Intratumoral injections of L19IL2
Malignant MelanomaClinical Trials (1)
NCT01253096Intratumoral Application of L19IL2 in Patients With Malignant Melanoma
Phase 2L19TNF
GliomaClinical Trials (1)
NCT07120984A Study to Evaluate the Safety and Efficacy of L19TNF With Alkylating Chemotherapy for Patients With Recurrent IDH-mutant Astrocytoma or Oligodendroglioma
Phase 2L19IL2
Melanoma Stage IIIL19IL2/L19TNF
Locally Advanced Basal Cell CarcinomaClinical Trials (1)
NCT07227870L19IL2/TNF in Patients With Basal Cell Carcinoma
Phase 2Dacarbazine
Soft Tissue SarcomaClinical Trials (1)
NCT04733183Efficacy and Safety of L19TNF in Previously Treated Patients with Advanced Stage or Metastatic Soft-tissue Sarcoma
Phase 2L19IL2/L19TNF
Locally Advanced Cutaneous Squamous Cell CarcinomaClinical Trials (1)
NCT07228442L19IL2/L19TNF in Patients With Cutaneous Squamous Cell Carcinoma
Phase 2Arm 1: L19IL2 + Dacarbazine
Metastatic MelanomaClinical Trials (1)
NCT01055522Clinical Study Phase II of L19IL2 in Combination With Dacarbazine in Patients With Metastatic Melanoma
Phase 2Daromun
Melanoma Stage IIIBClinical Trials (1)
NCT03567889Efficacy of Daromun Neoadjuvant Intratumoral Treatment in Clinical Stage IIIB/C/D Melanoma Patients
Phase 3Onfekafusp alfa
Soft Tissue SarcomaClinical Trials (1)
NCT04650984A Study Comparing the Efficacy of L19TNF+Doxorubicin vs Doxorubicin Alone as First-line Therapy in Patients With Advanced or Metastatic Soft Tissue Sarcoma
Phase 3L19IL2 + L19TNF
Malignant MelanomaClinical Trials (1)
NCT02938299Neoadjuvant L19IL2/L19TNF- Pivotal Study
Phase 3Open Jobs (12)
MEDICAL ADVISOR
Siena - Italy
Clinical1mo ago
SENIOR REGULATORY AFFAIRS SPECIALIST
Siena - Italy
Clinical1mo ago
ADMINISTRATIVE MANAGER
Siena - Italy
Others1mo ago
DEPUTY CHIEF MEDICAL OFFICER
Siena - Italy, Zurich – Switzerland
Clinical1mo ago
GMP QUALITY ASSURANCE SPECIALIST
Siena - Italy
QA1mo ago
CLINICAL RESEARCH ASSOCIATE
Siena - Italy
Clinical1mo ago
INTERN FINANCIAL OFFICE
Siena - Italy
Others1mo ago
GRADUATES IN BIOLOGY, BIOTECHNOLOGY, CHEMISTRY
Siena - Italy
QC & Analytical, QA1mo ago
OPERATORE PULIZIE E MANUTENZIONE AREE VERDI
Siena - Italy
Others1mo ago
INFRASTRUCTURE PROJECT ENGINEER (GEOMETRA / INGEGNERE CIVILE / ARCHITETTO)
Siena - Italy
Others4mo ago
PROCESS & COMPUTER SYSTEM VALIDATION SPECIALIST (GCP)
Siena - Italy
QA4mo ago
EXECUTIVE ASSISTANT
Siena - Italy
Others5mo ago
Interview Prep Quick Facts
Founded: 1996
Portfolio: 45 clinical trials
Top TAs: Oncology, Immunology
Open Roles: 12 active jobs