Gastrointestinal Stromal Tumor (GIST)

Oncology
2
Pipeline Programs
3
Companies
3
Clinical Trials
1 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
1
0
1
0
0
0
Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

Small Molecule
2100%
+ 1 programs with unclassified modality

Competitive Landscape

3 companies ranked by most advanced pipeline stage

Astex Pharmaceuticals
Astex PharmaceuticalsUK - Cambridge
1 program
1
AT13387 and ImatinibPhase 2Small Molecule1 trial
Active Trials
NCT01294202CompletedEst. Jul 2014
Kura Oncology
Kura OncologySAN DIEGO, CA
1 program
1
ziftomenibPhase 1Small Molecule1 trial
Active Trials
NCT06655246Recruiting157Est. Dec 2028
Heidelberg Pharma
Heidelberg PharmaGermany - Ladenburg
1 program
Dual Energy CTN/A1 trial
Active Trials
NCT03404076Completed93Est. Dec 2020

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
2028
Astex PharmaceuticalsAT13387 and Imatinib
Kura Oncologyziftomenib
Heidelberg PharmaDual Energy CT

Clinical Trials (3)

Total enrollment: 250 patients across 3 trials

A Study to Investigate the Safety and Efficacy of AT13387, Alone or in Combination With Imatinib, in Patients With GIST

Start: Mar 2011Est. completion: Jul 2014
Phase 2Completed

A Study of Ziftomenib in Combination With Imatinib in Patients With Advanced Gastrointestinal Stromal Tumors (GIST)

Start: Mar 2025Est. completion: Dec 2028157 patients
Phase 1Recruiting

Unifying Advanced Treatment With Advanced Imaging

Start: Dec 2014Est. completion: Dec 202093 patients
N/ACompleted

Related Jobs in Oncology

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

1 actively recruiting trials targeting 250 patients
Small Molecule is the dominant modality (100% of programs)
3 companies competing in this space