Fuchs Endothelial Corneal Dystrophy

Ophthalmology
2
Pipeline Programs
3
Companies
3
Clinical Trials
2 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
2
0
0
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

3 companies ranked by most advanced pipeline stage

Design Therapeutics
1 program
1
DT-168Phase 21 trial
Active Trials
NCT07024693RecruitingEst. Dec 2026
S
SantenCA - Emeryville
1 program
1
STN1010904 ophthalmic suspension 0.03% BIDPhase 21 trial
Active Trials
NCT05376176Completed86Est. May 2025
Heidelberg Pharma
Heidelberg PharmaGermany - Ladenburg
1 program
Duration of Supine PositioningN/A1 trial
Active Trials
NCT07373821Recruiting102Est. Mar 2027

Trial Timeline

Clinical trial activity over time

2022
2023
2024
2025
2026
2027
Design TherapeuticsDT-168
SantenSTN1010904 ophthalmic suspension 0.03% BID
Heidelberg PharmaDuration of Supine Positioning

Clinical Trials (3)

Total enrollment: 188 patients across 3 trials

DT-168 in Keratoplasty Patients With Fuchs Endothelial Corneal Dystrophy

Start: Jul 2025Est. completion: Dec 2026
Phase 2Recruiting
NCT05376176SantenSTN1010904 ophthalmic suspension 0.03% BID

A Multicenter Study Assessing the Efficacy and Safety of STN1010904 Ophthalmic Suspension 0.03% and 0.1% Compared With Vehicle in Subjects With Fuchs Endothelial Corneal Dystrophy (FECD)

Start: May 2022Est. completion: May 202586 patients
Phase 2Completed
NCT07373821Heidelberg PharmaDuration of Supine Positioning

Influence of Supine Positioning on the Outcomes After Descemet Membrane Endothelial Keratoplasty (DMEK)

Start: Oct 2025Est. completion: Mar 2027102 patients
N/ARecruiting

Related Jobs in Ophthalmology

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

2 actively recruiting trials targeting 188 patients
3 companies competing in this space