NDAORALTABLET
Approved
Jan 2012
Lifecycle
Peak
Competitive Pressure
0/100
Clinical Trials
20
Data completeness
6/8 — Strong
INLYTA (axitinib) by Pfizer is receptor tyrosine kinase inhibitors [moa]. First approved in 2012.
Drug data last refreshed 8h ago · AI intelligence enriched 1mo ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
INLYTA (axitinib) is an oral receptor tyrosine kinase inhibitor approved in 2012 for advanced renal cell carcinoma. It works by blocking multiple kinase pathways that drive tumor growth and angiogenesis. The drug is administered as an oral tablet and represents a mature, established therapy in the oncology kinase inhibitor class.
$0.467BPart D
Peak10.7 years to LOEPeak lifecycle status with $467M in Part D spending indicates a mature, stable commercial franchise with established field infrastructure and brand awareness.
Mechanism of Action
Receptor Tyrosine Kinase Inhibitors
Pharmacologic Class:
Kinase Inhibitor
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (20)
Study to Evaluate Long-Term Safety of Intravitreal OTX-TKI (Axitinib Implant) in Participants With Neovascular Age-Related Macular Degeneration Who Successfully Completed 2-Year OTX-TKI-2023-AMD-301 or OTX-TKI-2023-AMD-303 Study
Started Apr 2026
850 enrolled
Neovascular Age-Related Macular Degeneration (nAMD)
A Study of Sasanlimab, Palbociclib and Axitinib in Metastatic Renal Cell Carcinoma
Started Nov 2025
25 enrolled
Metastatic Renal Cell CarcinomaMetastatic Renal CancerRenal Cell Carcinoma+3 more
Envafolimab Combined With Axitinib as First-Line Treatment for Patients With Advanced Renal Cell Carcinoma
Started Sep 2025
30 enrolled
Advanced Renal Cell Carcinoma (aRCC)
Study to Evaluate the Efficacy and Safety of Intravitreal OTX-TKI (Axitinib Implant) in Subjects With Neovascular Age- Related Macular Degeneration
Started Nov 2024
825 enrolled
Neovascular Age-related Macular Degeneration
Avelumab, Palbociclib and Axitinib in Advanced RCC
Started May 2024
0Advanced Clear Cell Renal Cell Carcinoma
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.