Diastolic Heart Failure

Cardiovascular
1
Pipeline Programs
3
Companies
3
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
1
0
0
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

3 companies ranked by most advanced pipeline stage

GS
Gilead SciencesFOSTER CITY, CA
1 program
1
RanolazinePhase 21 trial
Active Trials
NCT01163734Completed20Est. Feb 2011
R
ResMedCA - San Diego
1 program
Adaptive servo ventilationN/A1 trial
Active Trials
NCT02254382Terminated2Est. Mar 2017
Abbott
AbbottABBOTT PARK, IL
1 program
Biventricular pacemakerN/A1 trial
Active Trials
NCT03338374Completed10Est. May 2022

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
Gilead SciencesRanolazine
AbbottBiventricular pacemaker
ResMedAdaptive servo ventilation

Clinical Trials (3)

Total enrollment: 32 patients across 3 trials

NCT01163734Gilead SciencesRanolazine

Ranolazine in Diastolic Heart Failure

Start: Apr 2010Est. completion: Feb 201120 patients
Phase 2Completed
NCT03338374AbbottBiventricular pacemaker

Cardiac Resynchronisation Therapy Versus Rate-responsive Pacing in Heart Failure With Preserved Ejection Fraction

Start: Nov 2017Est. completion: May 202210 patients
N/ACompleted
NCT02254382ResMedAdaptive servo ventilation

Positive Airway Pressure Therapy Study in Sleep Apnea and Diastolic Heart Failure

Start: Mar 2016Est. completion: Mar 20172 patients
N/ATerminated

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Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

3 companies competing in this space

Related Indications

Hypertension(361)Heart Failure(347)Coronary Artery Disease(302)Atrial Fibrillation(290)Pulmonary Arterial Hypertension(106)Acute Coronary Syndrome(67)Pulmonary Hypertension(57)Atherosclerosis(44)Hypertension, Pulmonary(34)Essential Hypertension(32)