Dedifferentiated Liposarcoma

Oncology
3
Pipeline Programs
4
Companies
4
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
1
1
1
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

4 companies ranked by most advanced pipeline stage

Rain Oncology
Rain OncologyCA - Newark
1 program
1
RAIN-32Phase 31 trial
Active Trials
NCT04979442TerminatedEst. Oct 2023
Karyopharm Therapeutics
1 program
1
SelinexorPhase 2/31 trial
Active Trials
NCT02606461CompletedEst. Oct 2021
CT
1 program
1
TQB3616 capsulePhase 21 trial
Active Trials
NCT05496569TerminatedEst. Sep 2025
Boehringer Ingelheim
Boehringer IngelheimINGELHEIM, Germany
1 program
Real-world Study of Dedifferentiated Liposarcoma Patients in ChinaN/A1 trial
Active Trials
NCT06115681Completed1,390Est. May 2024

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
Rain OncologyRAIN-32
Karyopharm TherapeuticsSelinexor
Chia Tai TianQing Pharmaceutical GroupTQB3616 capsule
Boehringer IngelheimReal-world Study of Dedifferentiated Liposarcoma Patients in China

Clinical Trials (4)

Total enrollment: 1,390 patients across 4 trials

NCT04979442Rain OncologyRAIN-32

Treatment of Milademetan Versus Trabectedin in Patient With Dedifferentiated Liposarcoma

Start: Jul 2021Est. completion: Oct 2023
Phase 3Terminated
NCT02606461Karyopharm TherapeuticsSelinexor

Selinexor in Advanced Liposarcoma

Start: Jan 2016Est. completion: Oct 2021
Phase 2/3Completed
NCT05496569Chia Tai TianQing Pharmaceutical GroupTQB3616 capsule

TQB3616 Capsules in the Treatment of Dedifferentiated Liposarcoma

Start: Aug 2022Est. completion: Sep 2025
Phase 2Terminated
NCT06115681Boehringer IngelheimReal-world Study of Dedifferentiated Liposarcoma Patients in China

Real-world Study of Dedifferentiated Liposarcoma Patients in China

Start: Mar 2024Est. completion: May 20241,390 patients
N/ACompleted

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Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

1 late-stage (Phase 3) programs — potential near-term approvals
4 companies competing in this space

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