Cutaneous Squamous Cell Carcinoma (CSCC)

Oncology
2
Pipeline Programs
2
Companies
3
Clinical Trials
2 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
1
0
1
0
Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

Monoclonal Antibody
3100%

Competitive Landscape

2 companies ranked by most advanced pipeline stage

Regeneron
RegeneronTARRYTOWN, NY
2 programs
1
CemiplimabPhase 3Monoclonal Antibody1 trial
CemiplimabN/AMonoclonal Antibody1 trial
Active Trials
NCT07064330Recruiting30Est. Jun 2027
NCT06585410Recruiting369Est. May 2030
LB
Lepu BiopharmaChina - Shanghai
1 program
1
PucotenlimabPhase 2Monoclonal Antibody1 trial
Active Trials
NCT07394244Not Yet RecruitingEst. Dec 2028

Trial Timeline

Clinical trial activity over time

2025
2026
2027
2028
2029
2030
RegeneronCemiplimab
Lepu BiopharmaPucotenlimab
RegeneronCemiplimab

Clinical Trials (3)

Total enrollment: 399 patients across 3 trials

NCT06585410RegeneronCemiplimab

Study of Intralesional Cemiplimab in Adult Patients With Early Stage Cutaneous Squamous Cell Carcinoma

Start: Jan 2025Est. completion: May 2030369 patients
Phase 3Recruiting
NCT07394244Lepu BiopharmaPucotenlimab

Pucotenlimab Combined With Becotatug Vedotin in Advanced Cutaneous Squamous Cell Carcinoma

Start: Jan 2026Est. completion: Dec 2028
Phase 2Not Yet Recruiting
NCT07064330RegeneronCemiplimab

Next-gen Flow Cytometry to Find Immune Profiles, Treatment Response, and Toxicity Markers in Skin Cancer Patients Treated With Cemiplimab.

Start: Jul 2025Est. completion: Jun 202730 patients
N/ARecruiting

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Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

1 late-stage (Phase 3) programs — potential near-term approvals
2 actively recruiting trials targeting 399 patients
2 companies competing in this space

Related Indications

Breast Cancer(530)Non-small Cell Lung Cancer(373)Prostate Cancer(371)Multiple Myeloma(244)Advanced Solid Tumors(221)Acute Myeloid Leukemia(204)Cancer(187)Neoplasms(173)Colorectal Cancer(166)Advanced Solid Tumor(165)