Chronic Kidney Failure

Nephrology
2
Pipeline Programs
2
Companies
7
Clinical Trials
1 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
2
0
0
0
0
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

2 companies ranked by most advanced pipeline stage

BI
Baxter InternationalIL - Deerfield
6 programs
1
Decision AidPhase 11 trial
Cartridge blood setN/A1 trial
Ease of Use and Blood Clotting for the Gambro Polyflux HD-C4 Big DialyzerN/A1 trial
Evodial hemodialysers and Evodia blood linesN/A1 trial
MCO-Ci 400N/A1 trial
+1 more programs
Active Trials
NCT00804453Completed16Est. Nov 2008
NCT00659724Completed33Est. May 2008
NCT00781690Completed53Est. Feb 2010
+3 more trials
M&
Merck & Co.RAHWAY, NJ
1 program
1
MK-2828Phase 11 trial
Active Trials
NCT07348237Recruiting24Est. Aug 2026

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
Merck & Co.MK-2828
Baxter InternationalDecision Aid
Baxter InternationalTheranova 400 Dialyzer
Baxter InternationalMCO-Ci 400
Baxter InternationalCartridge blood set
Baxter InternationalEvodial hemodialysers and Evodia blood lines
Baxter InternationalEase of Use and Blood Clotting for the Gambro Polyflux HD-C4 Big Dialyzer

Clinical Trials (7)

Total enrollment: 987 patients across 7 trials

NCT07348237Merck & Co.MK-2828

A Clinical Trial of MK-2828 in People With Kidney Disease (MK-2828-006)

Start: Mar 2026Est. completion: Aug 202624 patients
Phase 1Recruiting
NCT01671228Baxter InternationalDecision Aid

Developing and Evaluating the Yorkshire Dialysis Decision Aid

Start: Jan 2011Est. completion: Mar 2014488 patients
Phase 1Completed
NCT05309291Baxter InternationalTheranova 400 Dialyzer

Theranova Randomized, Controlled, Trial (RCT) in China

Start: Jun 2022Est. completion: Jul 2023323 patients
N/ACompleted
NCT02084381Baxter InternationalMCO-Ci 400

PERCI- Medium Cut Off (MCO)

Start: Feb 2014Est. completion: Feb 201550 patients
N/ACompleted
NCT00804453Baxter InternationalCartridge blood set

Evaluation of the Biocompatibility of Cartridge Blood Set Versus Standard Blood Line

Start: Nov 2008Est. completion: Nov 200816 patients
N/ACompleted
NCT00781690Baxter InternationalEvodial hemodialysers and Evodia blood lines

Reduction of Heparin Dose in Dialysis With Evodial System

Start: Sep 2008Est. completion: Feb 201053 patients
N/ACompleted
NCT00659724Baxter InternationalEase of Use and Blood Clotting for the Gambro Polyflux HD-C4 Big Dialyzer

Ease of Use and Blood Clotting for the Gambro Polyflux HD-C4 Big Dialyzer

Start: Mar 2008Est. completion: May 200833 patients
N/ACompleted

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Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

1 actively recruiting trials targeting 987 patients
2 companies competing in this space

Related Indications

Chronic Kidney Disease(101)End Stage Renal Disease(88)Renal Impairment(71)Kidney Transplantation(50)Renal Insufficiency(32)Chronic Kidney Diseases(26)Acute Kidney Injury(22)Diabetic Nephropathies(20)Kidney Diseases(20)Kidney Transplant(19)