Choroidal Melanoma
Oncology
2
Pipeline Programs
2
Companies
4
Clinical Trials
3 recruiting
0
Approved Products
Pipeline by Development Stage
Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
1
0
0
0
1
0
Early DiscoveryClinical DevelopmentMarket
Drug Modality Breakdown
Monoclonal Antibody
1100%
+ 3 programs with unclassified modality
Competitive Landscape
2 companies ranked by most advanced pipeline stage
Aura BiosciencesMA - Boston
3 programs1
Bel-sarPhase 31 trial
A Registry of Subjects With Primary Indeterminate Lesions or Choroidal MelanomaN/A1 trial
Non-interventional, digital, patient-reported, real-world studyN/A1 trial
Active Trials
Trial Timeline
Clinical trial activity over time
2021
2022
2023
2024
2025
2026
2027
2028
2029
Aura BiosciencesBel-sar
Genentechranibizumab
Aura BiosciencesNon-interventional, digital, patient-reported, real-world study
Aura BiosciencesA Registry of Subjects With Primary Indeterminate Lesions or Choroidal Melanoma
Clinical Trials (4)
Total enrollment: 40 patients across 4 trials
A Phase 3 Randomized, Masked, Controlled Trial to Evaluate Efficacy and Safety of Belzupacap Sarotalocan (AU-011) Treatment Compared to Sham Control in Subjects With Primary Indeterminate Lesions or Small Choroidal Melanoma
Start: Dec 2023Est. completion: Aug 2028
Phase 3Recruiting
Ranibizumab in Combination With Proton Beam Irradiation for Choroidal Melanoma
Start: Jun 2008Est. completion: Sep 201640 patients
Phase 1Completed
Choroidal Melanoma Patient-Reported Outcome Study (CM-PRO) in a Subset of AU-011-301 (CoMpass) Subjects
Start: Nov 2025Est. completion: Aug 2028
N/ARecruiting
NCT03941379Aura BiosciencesA Registry of Subjects With Primary Indeterminate Lesions or Choroidal Melanoma
A Registry of Subjects With Primary Indeterminate Lesions or Choroidal Melanoma
Start: Mar 2019Est. completion: Dec 2029
N/ARecruiting
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Phase Legend
Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available
Key Insights
1 late-stage (Phase 3) programs — potential near-term approvals
3 actively recruiting trials targeting 40 patients
2 companies competing in this space