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Cervix Cancer

Oncology
7
Pipeline Programs
11
Companies
7
Clinical Trials
1 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
5
0
2
0
0
0
Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

Monoclonal Antibody
6100%
+ 7 programs with unclassified modality

Oncology is a $53.9B market in consolidation, dominated by a handful of megacap players with blockbuster franchises approaching patent expiration.

$53.9B marketConsolidating→ Stable30 products15 companies

Key Trends

  • Heavy patent cliff exposure (REVLIMID $3.9B LOE 2028, JAKAFI $1.9B LOE 2028)
  • Kinase inhibitors and immunomodulatory agents dominate spend; limited diversification in top 10
  • Clinical trial volume remains exceptionally high (29,145 trials) but concentration in Phase 1-2 signals early-stage pipeline challenges

Career Verdict

Strong near-term opportunity for R&D and medical affairs roles, but competitive landscape and patent cliff urgency favor specialists over generalists.

AI-generated market analysis based on FDA, CMS, ClinicalTrials.gov, and hiring data

Market Leaders

#1ELIQUISStable
$18.3B
Bristol Myers Squibb·Launch15.0yr
#2FARXIGAStable
$4.3B
AstraZeneca·Peak15.4yr
#3REVLIMIDDeclining
$3.9B
Bristol Myers Squibb·LOE Approaching1.8yr
#4XTANDIStable
$2.6B
Astellas·Peak10.7yr
#5IMBRUVICAStable
$2.4B
AbbVie·Peak8.9yr

Drug Class Breakdown

FXa Inhibitors
$18.3B(34%)

concentrated in single product

SGLT2 Inhibitors
$4.3B(8%)

single dominant product

Kinase Inhibitors
$4.0B(7%)

multi-product class, competitive

Immunomodulatory Agents (Cereblon)
$3.9B(7%)

facing near-term patent cliff

Androgen Receptor Antagonists
$2.6B(5%)

prostate cancer specialty

Protein Kinase Inhibitors
$2.4B(4%)

niche hematologic oncology

JAK Inhibitors
$1.9B(4%)

near-term LOE exposure

Career Outlook

Stable

Oncology remains a premium therapeutic area but faces structural headwinds: top 10 products account for >80% of spend, patent cliffs loom (REVLIMID 2028), and late-stage pipeline thinness suggests slower near-term growth. However, high trial volume and consolidation create demand for specialized expertise in regulatory, clinical operations, and lifecycle management. Pharma professionals with kinase inhibitor, immunomodulatory, or ADC experience are in highest demand.

Breaking In

Entry-level candidates should target CROs (Thermo Fisher, IQVIA), emerging biotech (BeiGene, BeOne), or contract manufacturing; oncology specialization requires demonstrated domain knowledge.

For Experienced Professionals

Experienced professionals should focus on lifecycle/patent strategy roles (high salary, low headcount) or pivot to emerging modalities (ADCs, bispecifics) to avoid commoditization in crowded kinase inhibitor space.

In-Demand Skills

Regulatory strategy & PDUFA navigationKinase inhibitor development (small molecule)Clinical trial operations & site managementLifecycle management & patent strategyMedical affairs (oncology-specific science)Manufacturing scale-up (small molecule & biotech)

Best For

Regulatory Affairs ManagerClinical Operations ManagerMedical Science Liaison (MSL) — OncologyLifecycle ManagerR&D Scientist (medicinal chemistry, ADME)Manufacturing Engineer

Hiring Landscape

$102K–$266K

Oncology hiring is actively concentrated at Thermo Fisher Scientific (CRO/CDMO services, 559 jobs), AstraZeneca (208 jobs), and emerging biotech players like BeiGene (185 jobs). Commercial roles dominate (412 jobs, $136K avg) but R&D positions offer the highest salary premium ($199K avg, 347 roles). Patent cliff urgency is creating acute demand for regulatory, CMC, and lifecycle management expertise.

1,946
Open Roles
5
Companies Hiring
5
Departments

Top Hiring Companies

208Stable
185Growing
167Growing
147Growing

By Department

Commercial(21%)
$136K
Research & Development(18%)
$199K
Clinical Operations(5%)
$181K
Medical Affairs(4%)
$266K
Manufacturing(5%)
$102K

Strong near-term hiring momentum, especially in CRO/CDMO and emerging biotech; Medical Affairs offers highest compensation but limited headcount.

Competitive Landscape

10 companies ranked by most advanced pipeline stage

MSD
MSDIreland - Ballydine
2 programs
1
1
PembrolizumabPhase 2Monoclonal Antibody
PembrolizumabPhase 1Monoclonal Antibody
Sharp Therapeutics
Sharp TherapeuticsPA - Pittsburgh
2 programs
1
1
PembrolizumabPhase 2Monoclonal Antibody1 trial
PembrolizumabPhase 1Monoclonal Antibody1 trial
Active Trials
NCT03144466Terminated1Est. Jan 2019
NCT06266338Recruiting30Est. Oct 2027
Kite Pharma
Kite PharmaCA - El Segundo
1 program
1
Artesunate pessaryPhase 11 trial
Active Trials
NCT06165614Completed17Est. Apr 2025
Human BioSciences
Human BioSciencesWV - Martinsburg
1 program
1
Artesunate pessaryPhase 11 trial
Active Trials
NCT06263582Completed12Est. Aug 2024
ViiV Healthcare
ViiV HealthcareNC - Durham
1 program
1
TopotecanPhase 1
Gilead Sciences
Gilead SciencesFOSTER CITY, CA
2 programs
Artesunate pessaryPHASE_1
Artesunate pessaryPHASE_1
Mauna Kea Technologies
1 program
Confocal Laser EndomicroscopyN/A1 trial
Active Trials
NCT02221076Completed16Est. Apr 2016
Bristol Myers Squibb
1 program
Nivolumab and IpilimumabN/AMonoclonal Antibody1 trial
Active Trials
NCT04256213Completed40Est. Aug 2024
GSK
GSKLONDON, United Kingdom
1 program
TopotecanPHASE_11 trial
Active Trials
NCT00322920Terminated30
Merck & Co.
Merck & Co.RAHWAY, NJ
1 program
PembrolizumabPHASE_2Monoclonal Antibody

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
Sharp TherapeuticsPembrolizumab
Human BioSciencesArtesunate pessary
Kite PharmaArtesunate pessary
Sharp TherapeuticsPembrolizumab
GSKTopotecan
Bristol Myers SquibbNivolumab and Ipilimumab
Mauna Kea TechnologiesConfocal Laser Endomicroscopy

Clinical Trials (7)

Total enrollment: 146 patients across 7 trials

Study of Pembrolizumab and Lenvatinib in Metastatic and Recurrent Cervix Cancer (LenPem Cervix)

Start: Mar 2024Est. completion: Oct 202730 patients
Phase 2Recruiting

Pharmacokinetics of Intravaginal, Self-administered Artesunate Vaginal Pessaries Among Women in Kenya

Start: May 2024Est. completion: Aug 202412 patients
Phase 1Completed
NCT06165614Kite PharmaArtesunate pessary

Artesunate Pessaries (Vaginal Inserts) for Cervical Precancer in Kenya

Start: Mar 2024Est. completion: Apr 202517 patients
Phase 1Completed

A Study of Pembrolizumab And Platinum With Radiotherapy in Cervix Cancer

Start: Dec 2017Est. completion: Jan 20191 patients
Phase 1Terminated

Efficacy Study of Weekly Topotecan With Cisplatin in Advanced Stage or Recurrent Cervical Cancer

Start: Jul 200530 patients
Phase 1Terminated
NCT04256213Bristol Myers SquibbNivolumab and Ipilimumab

COL Immunotherapy Before Radiochimio + Ipilimumab

Start: Jul 2020Est. completion: Aug 202440 patients
N/ACompleted
NCT02221076Mauna Kea TechnologiesConfocal Laser Endomicroscopy

Probe-based and Needle-based Confocal Laser Endomicroscopy During Gynaecological Procedures.

Start: Jul 2014Est. completion: Apr 201616 patients
N/ACompleted

Related Jobs in Oncology

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

1 actively recruiting trials targeting 146 patients
11 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.