Cervical Cancer

Oncology
20
Pipeline Programs
19
Companies
49
Clinical Trials
5 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
2
1
10
1
4
2
Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

Monoclonal Antibody
467%
ADC
233%
+ 19 programs with unclassified modality

Competitive Landscape

14 companies ranked by most advanced pipeline stage

M&
Merck & Co.RAHWAY, NJ
7 programs
2
1
V501Phase 41 trial
V501, Gardasil, Quadrivalent Human PapillomavirusPhase 31 trial
V503Phase 35 trials
Distribution of Human Papillomavirus (HPV) Genotypes in Patients With Cervical Cancer From CroatiaN/A1 trial
Health Care Decisions for Female Adolescents: The Role of Mothers and Daughters in Decision MakingN/A1 trial
+2 more programs
Active Trials
NCT01385436Unknown400Est. Dec 2013
NCT00807898Completed136Est. Jan 2011
NCT00937547Completed329Est. Jul 2011
+8 more trials
Pfizer
PfizerNEW YORK, NY
2 programs
1
1
TIVDAKPhase 41 trial
Tisotumab VedotinPhase 1/2ADC5 trials
Active Trials
NCT04697628Completed502Est. Jan 2026
NCT03657043Completed98Est. Feb 2022
NCT03786081Active Not Recruiting214Est. Mar 2026
+3 more trials
LP
Lee's PharmaceuticalChina - Guangzhou
2 programs
1
1
Socazolimab+cisplatin/carboplatin+paclitaxel+BevacizumabPhase 3Monoclonal Antibody1 trial
ZKAB001 5mg/kgPhase 11 trial
Active Trials
NCT03676959Unknown101Est. Oct 2022
NCT06459687Recruiting440Est. Sep 2028
Walvax Biotechnology
Walvax BiotechnologyChina - Kunming
1 program
1
Zerun HPV-9Phase 31 trial
Active Trials
NCT05580341UnknownEst. Dec 2023
Qilu Pharmaceutical
Qilu PharmaceuticalChina - Jinan
4 programs
3
1
QL1604Phase 2/31 trial
QL1706Phase 21 trial
QL1706Phase 21 trial
Sacituzumab tirumotecan plus IparomlimabPhase 2Monoclonal Antibody1 trial
Active Trials
NCT05179317UnknownEst. Dec 2023
NCT05557565UnknownEst. Jun 2023
NCT07348861Not Yet RecruitingEst. Jan 2028
+1 more trials
Genentech
GenentechCA - Oceanside
1 program
1
BevacizumabPhase 2Monoclonal Antibody1 trial
Active Trials
NCT00600210Withdrawn0Est. Apr 2011
GSK
GSKLONDON, United Kingdom
1 program
1
No Further TreatmentPhase 21 trial
Active Trials
NCT03833479Active Not Recruiting134Est. Dec 2025
Precigen
PrecigenGERMANTOWN, MD
1 program
1
PRGN-2009 plus PembrolizumabPhase 2Monoclonal Antibody1 trial
Active Trials
NCT06157151Recruiting46Est. Jan 2028
GS
Gilead SciencesFOSTER CITY, CA
1 program
1
Sacituzumab govitecanPhase 2ADC1 trial
Active Trials
NCT05838521Recruiting20Est. Jun 2028
CT
1 program
1
TQB2868 injectionPhase 21 trial
Active Trials
NCT05998941WithdrawnEst. Jun 2025
DS
Daiichi SankyoChina - Shanghai
1 program
1
exatecan mesylatePhase 25 trials
Active Trials
NCT00055939CompletedEst. Apr 2006
NCT00055952CompletedEst. Apr 2006
NCT00005938CompletedEst. Apr 2005
+2 more trials
Alliance Pharmaceuticals
1 program
1
imiquimodPhase 21 trial
Active Trials
NCT00031759Completed57Est. Feb 2010
IB
Instil BioDALLAS, TX
1 program
1
ITIL-168Phase 11 trial
Active Trials
NCT05393635WithdrawnEst. Dec 2022
HM
Hua MedicineChina - Shanghai
1 program
Total Laparoscopic or Robotic Radical HysterectomyN/A1 trial
Active Trials
NCT04934982Recruiting690Est. Jun 2026

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
2028
2029
2030
2031
PfizerTIVDAK
Merck & Co.V501
Lee's PharmaceuticalSocazolimab+cisplatin/carboplatin+paclitaxel+Bevacizumab
Walvax BiotechnologyZerun HPV-9
PfizerTisotumab Vedotin
Merck & Co.V503
Merck & Co.V503
Merck & Co.V503
Merck & Co.V503
Merck & Co.V503
Merck & Co.V503
Merck & Co.V503
Merck & Co.V503
Merck & Co.V503
Merck & Co.V503

Showing 15 of 49 trials with date data

Clinical Trials (49)

Total enrollment: 42,966 patients across 49 trials

Ocular Assessments in Patients Treated With Tivdak® in Recurrent or Metastatic Cervical Cancer

Start: May 2025Est. completion: Dec 2028100 patients
Phase 4Recruiting

V501 Safety and Efficacy Study in Japanese Women Aged 16 to 26 Years (V501-110)

Start: Nov 2011Est. completion: Aug 20161,030 patients
Phase 4Completed
NCT06459687Lee's PharmaceuticalSocazolimab+cisplatin/carboplatin+paclitaxel+Bevacizumab

Phase III Study of Socazolimab as First-Line Treatment in Persistent, Recurrent, or Metastatic Cervical Cancer

Start: Nov 2024Est. completion: Sep 2028440 patients
Phase 3Recruiting

Phase III Study Comparing the Immunogenicity of 9-valent HPV Recombinant Vaccine and Gardasil-9

Start: Sep 2022Est. completion: Dec 2023
Phase 3Unknown
NCT04697628PfizerTisotumab Vedotin

Tisotumab Vedotin vs Chemotherapy in Recurrent or Metastatic Cervical Cancer

Start: Feb 2021Est. completion: Jan 2026502 patients
Phase 3Completed

Efficacy, Immunogenicity and Safety of V503 in Chinese Women Aged 20-45 Years (V503-023)

Start: Jun 2019Est. completion: Mar 20286,000 patients
Phase 3Active Not Recruiting

Immunobridging Study of 9- Valent Human Papillomavirus (9vHPV) Vaccine (V503) in Chinese Females 9 to 45 Years of Age (V503-024)

Start: Apr 2019Est. completion: Feb 20251,990 patients
Phase 3Completed

Immunogenicity and Tolerability of Broad Spectrum Human Papillomavirus (HPV) Vaccine in Adult and Young Adult Women (V503-004)

Start: Sep 2017Est. completion: Nov 20181,212 patients
Phase 3Completed

A Phase III Study of a 2-dose Regimen of a Multivalent Human Papillomavirus (HPV) Vaccine (V503), Administered to 9 to 14 Year-olds and Compared to Young Women, 16 to 26 Years Old (V503-010)

Start: Dec 2013Est. completion: Jul 20171,518 patients
Phase 3Completed

Immunogenicity and Tolerability of V503 Versus GARDASIL (V503-009)

Start: Feb 2011Est. completion: Dec 2011600 patients
Phase 3Completed

A Study of the Safety, Tolerability, and Immunogenicity of a 9-valent Human Papillomavirus Vaccine ([9vHPV]; V503) Administered to 9- to 15-Year-Old Japanese Girls (V503-008).

Start: Jan 2011Est. completion: Aug 2013100 patients
Phase 3Completed

A Study of V503 Vaccine Given Concomitantly With REPEVAX™ in 11 to 15 Year Olds (V503-007)

Start: Apr 2010Est. completion: Jun 20111,054 patients
Phase 3Completed

A Study of V503 Given Concomitantly With Menactra™ and Adacel™ in 11 to 15 Year Olds (V503-005)

Start: Oct 2009Est. completion: Feb 20111,241 patients
Phase 3Completed

A Study of V503 (A Multivalent Human Papillomavirus [HPV] L1 Virus-Like Particle [VLP] Vaccine) in Preadolescents and Adolescents (V503-002)

Start: Aug 2009Est. completion: Apr 20213,074 patients
Phase 3Completed

Broad Spectrum HPV (Human Papillomavirus) Vaccine Study in 16-to 26-Year-Old Women (V503-001)

Start: Sep 2007Est. completion: Jul 201614,840 patients
Phase 3Completed
NCT00517309Merck & Co.V501, Gardasil, Quadrivalent Human Papillomavirus

Study to Test the Safety of HPV Vaccine in Women (V501-011)(COMPLETED)

Start: Dec 2001Est. completion: Jun 20041,877 patients
Phase 3Completed

QL1604 Plus Chemotherapy in Subjects With Stage IVB, Recurrent, or Metastatic Cervical Cancer

Start: Sep 2020Est. completion: Nov 2023
Phase 2/3Terminated
NCT07348861Qilu PharmaceuticalSacituzumab tirumotecan plus Iparomlimab

A Phase II Study of Neoadjuvant Sacituzumab Tirumotecan in Combination With Iparomlimab and Tuvonralimab in Locally Advanced Cervical Cancer

Start: Feb 2026Est. completion: Jan 2028
Phase 2Not Yet Recruiting
NCT06157151PrecigenPRGN-2009 plus Pembrolizumab

PRGN-2009 in Combination With Pembrolizumab Versus Pembrolizumab in Patients With Recurrent or Metastatic Cervical Cancer

Start: Mar 2025Est. completion: Jan 202846 patients
Phase 2Recruiting

A Trial of TQB2868 Plus Platinum-based Chemotherapy With or Without Bevacizumab in the First-line Treatment of Persistent, Recurrent, or Metastatic Cervical Cancer

Start: Aug 2023Est. completion: Jun 2025
Phase 2Withdrawn
NCT05838521Gilead SciencesSacituzumab govitecan

A Study of Sacituzumab Govitecan (IMMU-132) in Patients With Recurrent or Persistent Cervical Cancer

Start: Jun 2023Est. completion: Jun 202820 patients
Phase 2Recruiting

A Phase II Trial to Evaluate the Efficacy and Safety of QL1706 in Patients With Cervical Cancer

Start: Dec 2021Est. completion: Jun 2023
Phase 2Unknown

Safety and Efficacy Study of First-line Treatment With QL1706 Plus Chemotherapy With or Without Bevacizumab in Women With Recurrent, or Metastatic Cervical Cancer

Start: May 2021Est. completion: Dec 2023
Phase 2Unknown
NCT03833479GSKNo Further Treatment

TSR-042 as Maintenance Therapy for Patients With High-risk Locally Advanced Cervical Cancer After Chemo-radiation

Start: Jun 2019Est. completion: Dec 2025134 patients
Phase 2Active Not Recruiting
NCT03657043PfizerTisotumab Vedotin

A Study of Weekly Tisotumab Vedotin for Patients With Platinum-Resistant Ovarian Cancer With Safety Run-in (innovaTV 208)

Start: Mar 2019Est. completion: Feb 202298 patients
Phase 2Completed
NCT03485209PfizerTisotumab Vedotin

Efficacy and Safety Study of Tisotumab Vedotin for Patients With Solid Tumors

Start: Jun 2018Est. completion: Mar 2027352 patients
Phase 2Active Not Recruiting
NCT03438396PfizerTisotumab Vedotin

A Trial of Tisotumab Vedotin in Cervical Cancer

Start: Jun 2018Est. completion: Aug 2022102 patients
Phase 2Completed
NCT03245736PfizerTisotumab Vedotin

Tisotumab Vedotin Continued Treatment in Patients With Solid Tumors.

Start: Aug 2017Est. completion: Jan 20195 patients
Phase 2Completed

Neoadjuvant Bevacizumab and Carboplatin Followed by Concurrent Bevacizumab, Carboplatin and Radiotherapy in the Primary Treatment of Cervix Cancer

Start: Jan 2008Est. completion: Apr 20110
Phase 2Withdrawn
NCT00055939Daiichi Sankyoexatecan mesylate

Exatecan Mesylate in Treating Children With Relapsed or Refractory Rhabdomyosarcoma

Start: Jan 2003Est. completion: Apr 2006
Phase 2Completed
NCT00055952Daiichi Sankyoexatecan mesylate

Exatecan Mesylate in Treating Patients With Ewing's Sarcoma, Primitive Neuroectodermal Tumor, or Desmoplastic Small Round Cell Tumor

Start: Jan 2003Est. completion: Apr 2006
Phase 2Completed
NCT00005938Daiichi Sankyoexatecan mesylate

DX-8951f in Treating Patients With Biliary Cancer

Start: Mar 2000Est. completion: Apr 2005
Phase 2Completed
NCT00004866Daiichi Sankyoexatecan mesylate

DX-8951f in Treating Women Who Have Advanced or Recurrent Cancer of the Cervix

Start: Jan 2000Est. completion: Sep 2003
Phase 2Completed
NCT00004060Daiichi Sankyoexatecan mesylate

Chemotherapy in Treating Patients With Recurrent, Metastatic, or Unresectable Ovarian, Fallopian Tube, or Peritoneal Cancer

Start: Jul 1999Est. completion: Sep 2000
Phase 2Completed
NCT00004046Daiichi Sankyoexatecan mesylate

Chemotherapy in Treating Women With Metastatic Breast Cancer

Start: Jun 1999Est. completion: Apr 2002
Phase 2Completed

Imiquimod in Preventing Cervical Cancer in Women With Cervical Neoplasia

Start: Jun 1999Est. completion: Feb 201057 patients
Phase 2Completed
NCT03913741PfizerTisotumab Vedotin

A Trial of Tisotumab Vedotin in Japanese Subjects With Advanced Solid Malignancies

Start: Feb 2019Est. completion: Oct 202123 patients
Phase 1/2Completed
NCT03786081PfizerTisotumab Vedotin

Safety and Efficacy of Tisotumab Vedotin Monotherapy & in Combination With Other Cancer Agents in Subjects With Cervical Cancer

Start: Feb 2019Est. completion: Mar 2026214 patients
Phase 1/2Active Not Recruiting
NCT02552121PfizerTisotumab Vedotin

Tisotumab Vedotin (HuMax®-TF-ADC) Safety Study in Patients With Solid Tumors

Start: Nov 2015Est. completion: Dec 201733 patients
Phase 1/2Completed
NCT02001623PfizerTisotumab Vedotin

Tisotumab Vedotin (HuMax®-TF-ADC) Safety Study in Patients With Solid Tumors

Start: Nov 2013Est. completion: May 2019195 patients
Phase 1/2Completed

ITIL-168 in Advanced Solid Tumors

Start: Aug 2022Est. completion: Dec 2022
Phase 1Withdrawn

A Clinical Study of PD-L1 Antibody ZKAB001(Drug Code) in Recurrent or Metastatic Cervical Cancer

Start: Aug 2018Est. completion: Oct 2022101 patients
Phase 1Unknown
NCT00004212Daiichi Sankyoexatecan mesylate

DX-8951f in Treating Children With Advanced Solid Tumors or Lymphomas

Start: Sep 1999Est. completion: Apr 2004
Phase 1Completed
NCT00004047Daiichi Sankyoexatecan mesylate

Chemotherapy in Treating Patients Who Have Hematologic Cancer

Start: Jun 1999Est. completion: Apr 2005
Phase 1Completed
NCT04934982Hua MedicineTotal Laparoscopic or Robotic Radical Hysterectomy

Laparoscopic or Abdominal Radical Hysterectomy for Cervical Cancer(Stage IA1 With LVSI, IA2)

Start: Sep 2021Est. completion: Jun 2026690 patients
N/ARecruiting

Long-term Follow-up of Broad Spectrum Human Papillomavirus (HPV) Vaccine Study in Women (V503-021)

Start: Jan 2016Est. completion: Jan 20404,453 patients
N/AActive Not Recruiting
NCT01385436Merck & Co.Distribution of Human Papillomavirus (HPV) Genotypes in Patients With Cervical Cancer From Croatia

Distribution of Human Papillomavirus (HPV) Genotypes in Patients With Cervical Cancer From Croatia

Start: May 2010Est. completion: Dec 2013400 patients
N/AUnknown
NCT00937547Merck & Co.Human Papillomavirus Infection and Virus Genotyping in Uterine Cervix Cancer in Venezuela

Human Papillomavirus Infection and Virus Genotyping in Uterine Cervix Cancer in Venezuela

Start: Nov 2009Est. completion: Jul 2011329 patients
N/ACompleted
NCT00807898Merck & Co.Health Care Decisions for Female Adolescents: The Role of Mothers and Daughters in Decision Making

Health Care Decisions for Female Adolescents: The Role of Mothers and Daughters in Decision Making

Start: Jan 2009Est. completion: Jan 2011136 patients
N/ACompleted

Related Jobs in Oncology

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

4 late-stage (Phase 3) programs — potential near-term approvals
5 actively recruiting trials targeting 42,966 patients
19 companies competing in this space