NDATOPICALCREAM
Approved
Mar 2010
Lifecycle
Peak
Competitive Pressure
8/100
Clinical Trials
20
Data completeness
5/8 — Partial
ZYCLARA (imiquimod) by Bausch + Lomb is interferon inducers [moa]. First approved in 2010.
Drug data last refreshed 4h ago · AI intelligence enriched Yesterday
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
ZYCLARA (imiquimod) is a topical cream formulation of imiquimod, an interferon inducer that activates innate immunity at the application site. It is used to treat external genital warts, actinic keratosis, and superficial basal cell carcinoma. The drug works by stimulating local interferon production and immune cell activation to clear viral or malignant lesions.
$0.115MPart D
Peak3.6 years to LOEProduct is at peak maturity with modest Medicare spending; commercial team is likely optimized for maintenance rather than expansion.
Mechanism of Action
Interferon Inducers
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (20)
Cemiplimab Plus Imiquimod and Laser Therapy As Neoadjuvant Treatment In Cutaneous Basal Cell Carcinoma
Started Oct 2025
18 enrolled
Cutaneous Basal Cell Carcinoma
Effectiveness of Imiquimod Topical Cream in Early Stage Cutaneous T-cell Lymphoma
Started Apr 2020
0Mycosis Fungoides
Evaluation of VGX-3100 and Electroporation Alone or in Combination With Imiquimod for the Treatment of HPV-16 and/or HPV-18 Related Vulvar HSIL (Also Referred as: VIN 2 or VIN 3)
Started Aug 2017
33 enrolled
Vulvar High Grade Squamous Intraepithelial Lesion (HSIL)Vulvar DysplasiaVulvar Intraepithelial Neoplasia (VIN)+4 more
Safety and Efficacy of GX-188E Administered Via EP Plus GX-I7 or Imiquimod.
Started May 2017
50 enrolled
Cervical Intraepithelial Neoplasia 3
Topical Challenge With Omiganan and Imiquimod in Healthy Volunteers
Started Feb 2017
16 enrolled
Healthy
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.