Castration Resistant Prostate Cancer

Oncology
2
Pipeline Programs
3
Companies
17
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
1
0
1
0
0
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

2 companies ranked by most advanced pipeline stage

Achieve Life Sciences
1 program
1
OGX-427Phase 21 trial
Active Trials
NCT01120470CompletedEst. Jun 2014
Novartis
NovartisBASEL, Switzerland
1 program
1
SOM230Phase 15 trials
Active Trials
NCT02780882Withdrawn0Est. Jun 2019
NCT01646684Completed9Est. Nov 2018
NCT01637272Completed43Est. Aug 2015
+2 more trials

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
NovartisSOM230
NovartisSOM230
NovartisSOM230
NovartisSOM230
Achieve Life SciencesOGX-427
NovartisSOM230
NovartisSOM230
NovartisSOM230
NovartisSOM230
NovartisSOM230
NovartisSOM230
NovartisSOM230
NovartisSOM230
NovartisSOM230
NovartisSOM230

Showing 15 of 17 trials with date data

Clinical Trials (17)

Total enrollment: 532 patients across 17 trials

Efficacy and Safety of Pasireotide Administered Monthly in Patients With Cushing's Disease

Start: Nov 2011Est. completion: Dec 2016150 patients
Phase 3Completed

SOM230 Ectopic ACTH-producing Tumors

Start: Dec 2015Est. completion: Jun 20190
Phase 2Withdrawn

Phase II Study Evaluating Efficacy, Safety and Pharmacokinetics of Pasireotide in Patients With Dumping Syndrome

Start: Jan 2013Est. completion: Aug 201543 patients
Phase 2Completed

SOM230 LAR With Bortezomib and Dexamethasone for Refractory or Relapsed Multiple Myeloma

Start: Dec 2011Est. completion: Feb 20120
Phase 2Withdrawn

OGX-427 in Castration Resistant Prostate Cancer Patients

Start: Sep 2010Est. completion: Jun 2014
Phase 2Completed

Monthly SOM230C for Recurrent or Progressive Meningioma

Start: Mar 2009Est. completion: Jan 201634 patients
Phase 2Completed

Phase II Study of SOM230 in Patients With Recurrent or Progressive Meningioma

Start: Nov 2008Est. completion: Mar 20132 patients
Phase 2Terminated

A Study to Assess SOM230 in Patients With Pituitary Cushing's Disease

Start: Apr 200426 patients
Phase 2Completed

Study Comparing SOM230 Subcutaneously and Sandostatin Subcutaneously in Acromegalic Patients

Start: Mar 200462 patients
Phase 2Completed

Study Evaluating SOM230 in Patients With Metastatic Carcinoid Tumors

Start: Jan 2004Est. completion: Jul 200845 patients
Phase 2Completed

Phase 1 Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of Pasireotide LAR in Patients With Castration Resistant Prostate Cancer

Start: Mar 2013Est. completion: Nov 20189 patients
Phase 1Completed

A Phase I, Exploratory, Intra-patient Dose Escalation Study to Investigate the Preliminary Safety, Pharmacokinetics, and Anti-tumor Activity of Pasireotide (SOM230) s.c.Followed by Pasireotide LAR in Patients With Metastaticmelanoma or Metastatic Merkel Cell Carcinoma

Start: Nov 2012Est. completion: Apr 201510 patients
Phase 1Completed

A Phase l Study to Evaluate the Pharmacokinetics and Safety Pasireotide in Subjects With Varying Degrees of Renal Impairment Compared to Healthy Volunteers

Start: May 2012Est. completion: May 201450 patients
Phase 1Completed

Phase I Trial of Combination of FOLFIRI and SOM 230

Start: Sep 2011Est. completion: Dec 201516 patients
Phase 1Completed

Dose Escalation Study of Pasireotide (SOM230) in Patients With Advanced Neuroendocrine Tumors (NETs)

Start: Aug 2011Est. completion: Apr 201629 patients
Phase 1Completed

Pasireotide in Combination With RAD001 in Patients With Advanced Neuroendocrine Tumors

Start: Oct 2008Est. completion: Apr 201522 patients
Phase 1Completed

Pharmacokinetics and Safety of Single Subcutaneous Pasireotide (SOM230) in Subjects With Varying Degrees of Hepatic Function

Start: Jul 200834 patients
Phase 1Completed

Related Jobs in Oncology

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

3 companies competing in this space