Carcinoma, Pancreatic Ductal

Oncology
3
Pipeline Programs
3
Companies
4
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
2
1
0
0
0
Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

Cell Therapy
1100%
+ 2 programs with unclassified modality

Competitive Landscape

3 companies ranked by most advanced pipeline stage

Astellas
AstellasChina - Shenyang
1 program
1
AGS-1C4D4Phase 22 trials
Active Trials
NCT01608711Completed2Est. Nov 2015
NCT00902291Completed205Est. Apr 2012
Silence Therapeutics
Silence TherapeuticsGermany - Berlin
1 program
1
Atu027 & gemcitabine in lead in safety periodPhase 1/21 trial
Active Trials
NCT01808638CompletedEst. Jan 2016
Heidelberg Pharma
Heidelberg PharmaGermany - Ladenburg
1 program
1
CD318-CAR-T cellsPhase 1/2Cell Therapy1 trial
Active Trials
NCT07153289Not Yet Recruiting38Est. Dec 2028

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
2028
AstellasAGS-1C4D4
AstellasAGS-1C4D4
Heidelberg PharmaCD318-CAR-T cells
Silence TherapeuticsAtu027 & gemcitabine in lead in safety period

Clinical Trials (4)

Total enrollment: 245 patients across 4 trials

NCT01608711AstellasAGS-1C4D4

A Study of AGS-1C4D4 in Pancreatic Cancer Subjects Previously Treated in Protocol 2008002

Start: Aug 2012Est. completion: Nov 20152 patients
Phase 2Completed
NCT00902291AstellasAGS-1C4D4

A Study of AGS-1C4D4 Given in Combination With Gemcitabine in Subjects With Metastatic Pancreatic Cancer

Start: Apr 2009Est. completion: Apr 2012205 patients
Phase 2Completed
NCT07153289Heidelberg PharmaCD318-CAR-T cells

CD318-targeted CAR-T Cell Therapy in Patients With Pancreatic Cancer (ResCPa)

Start: Jul 2026Est. completion: Dec 202838 patients
Phase 1/2Not Yet Recruiting
NCT01808638Silence TherapeuticsAtu027 & gemcitabine in lead in safety period

Atu027 Plus Gemcitabine in Advanced or Metastatic Pancreatic Cancer (Atu027-I-02)

Start: Mar 2013Est. completion: Jan 2016
Phase 1/2Completed

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Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

3 companies competing in this space

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