Breast Neoplasm

Oncology
7
Pipeline Programs
8
Companies
9
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
2
1
3
0
1
0
Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

Small Molecule
1100%
+ 8 programs with unclassified modality

Competitive Landscape

7 companies ranked by most advanced pipeline stage

Achieve Life Sciences
1 program
1
TaxolPhase 31 trial
Active Trials
NCT00251095TerminatedEst. Sep 2007
M&
Merck & Co.RAHWAY, NJ
3 programs
2
Pegylated Liposomal DoxorubicinPhase 21 trial
Pegylated Lyposomal DoxorubicinPhase 21 trial
Pegylated Liposomal DoxorubicinN/A1 trial
Active Trials
NCT00736333Completed167Est. Jun 2010
NCT00687440Completed27Est. Oct 2008
NCT00779129Completed70Est. Aug 2007
Bayer
BayerLEVERKUSEN, Germany
1 program
1
SagopilonePhase 21 trial
Active Trials
NCT00313248Completed65Est. Nov 2008
E
EisaiChina - Liaoning
1 program
1
Eribulin MesylatePhase 1/21 trial
Active Trials
NCT02513472Completed258Est. Apr 2021
Providence Therapeutics
1 program
1
CyclophosphamidePhase 11 trial
Active Trials
NCT02950259CompletedEst. Sep 2025
Takeda
TakedaTOKYO, Japan
1 program
1
TAK-165Phase 11 trial
Active Trials
NCT00034281Completed16Est. Sep 2003
Pierre Fabre
Pierre FabreFrance - Aignan
1 program
NeratinibN/ASmall Molecule1 trial
Active Trials
NCT04388384Completed304Est. Sep 2024

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
Achieve Life SciencesTaxol
BayerSagopilone
Merck & Co.Pegylated Liposomal Doxorubicin
Merck & Co.Pegylated Lyposomal Doxorubicin
EisaiEribulin Mesylate
Providence TherapeuticsCyclophosphamide
TakedaTAK-165
Pierre FabreNeratinib
Merck & Co.Pegylated Liposomal Doxorubicin

Clinical Trials (9)

Total enrollment: 907 patients across 9 trials

NCT00251095Achieve Life SciencesTaxol

Comparison of Safety and Efficacy of TOCOSOL(R) Paclitaxel Versus Taxol(R) for Treatment of Metastatic Breast Cancer

Start: Sep 2005Est. completion: Sep 2007
Phase 3Terminated
NCT00313248BayerSagopilone

Evaluation of a New Agent for Treatment of Advanced Stage Breast Cancer

Start: Apr 2006Est. completion: Nov 200865 patients
Phase 2Completed
NCT00687440Merck & Co.Pegylated Liposomal Doxorubicin

A Study to Determine the Activity of Caelyx With Trastuzumab and Docetaxel in the Treatment of Metastatic Breast Cancer (Study P03679)

Start: Jul 2005Est. completion: Oct 200827 patients
Phase 2Completed
NCT00779129Merck & Co.Pegylated Lyposomal Doxorubicin

A Study to Evaluate Safety and Efficacy of Caelyx in Combination With Cyclophosphamide in the Treatment of Metastatic Breast Cancer (P02948)

Start: Mar 2003Est. completion: Aug 200770 patients
Phase 2Completed
NCT02513472EisaiEribulin Mesylate

Study to Evaluate the Efficacy and Safety of Eribulin Mesylate in Combination With Pembrolizumab in Participants With Metastatic Triple-Negative Breast Cancer (mTNBC)

Start: Aug 2015Est. completion: Apr 2021258 patients
Phase 1/2Completed
NCT02950259Providence TherapeuticsCyclophosphamide

Pre-operative IRX-2 in Early Stage Breast Cancer (ESBC)

Start: Feb 2017Est. completion: Sep 2025
Phase 1Completed
NCT00034281TakedaTAK-165

Safety and Tolerability Study of TAK-165 in Subjects With Tumors Expressing HER2

Start: Jun 2002Est. completion: Sep 200316 patients
Phase 1Completed
NCT04388384Pierre FabreNeratinib

Real-life Pan-HER-blockade With Neratinib

Start: Jul 2020Est. completion: Sep 2024304 patients
N/ACompleted
NCT00736333Merck & Co.Pegylated Liposomal Doxorubicin

A Study to Evaluate Safety and Tolerability in Patients With Metastatic Breast Cancer Receiving Treatment With Caelyx (Study P04878)(COMPLETED)

Start: Nov 2006Est. completion: Jun 2010167 patients
N/ACompleted

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Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

1 late-stage (Phase 3) programs — potential near-term approvals
8 companies competing in this space

Related Indications

Breast Cancer(530)Non-small Cell Lung Cancer(373)Prostate Cancer(371)Multiple Myeloma(244)Advanced Solid Tumors(221)Acute Myeloid Leukemia(204)Cancer(187)Neoplasms(173)Colorectal Cancer(166)Advanced Solid Tumor(165)