Autosomal Dominant Polycystic Kidney

Nephrology
3
Pipeline Programs
3
Companies
3
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
0
0
2
1
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

3 companies ranked by most advanced pipeline stage

Boehringer Ingelheim
Boehringer IngelheimINGELHEIM, Germany
1 program
1
Empagliflozin 10 MGPhase 41 trial
Active Trials
NCT06391450Active Not Recruiting44Est. May 2027
Biogen
BiogenCAMBRIDGE, MA
1 program
1
Bardoxolone methyl oral capsulePhase 31 trial
Active Trials
NCT03918447Terminated667Est. Aug 2023
Centessa Pharmaceuticals
1 program
1
LixivaptanPhase 31 trial
Active Trials
NCT04064346TerminatedEst. Aug 2022

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
Boehringer IngelheimEmpagliflozin 10 MG
Centessa PharmaceuticalsLixivaptan
BiogenBardoxolone methyl oral capsule

Clinical Trials (3)

Total enrollment: 711 patients across 3 trials

Study of Empagliflozin in Patients With Autosomal Dominant Polycystic Kidney Disease (EMPA-PKD)

Start: Jun 2024Est. completion: May 202744 patients
Phase 4Active Not Recruiting

Efficacy and Safety of Lixivaptan in the Treatment of Autosomal Dominant Polycystic Kidney Disease

Start: Oct 2021Est. completion: Aug 2022
Phase 3Terminated
NCT03918447BiogenBardoxolone methyl oral capsule

A Trial of Bardoxolone Methyl in Patients With ADPKD - FALCON

Start: May 2019Est. completion: Aug 2023667 patients
Phase 3Terminated

Related Jobs in Nephrology

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

2 late-stage (Phase 3) programs — potential near-term approvals
3 companies competing in this space