Advanced Intrahepatic Cholangiocarcinoma

Oncology
3
Pipeline Programs
3
Companies
2
Clinical Trials
2 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
2
1
0
0
Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

Monoclonal Antibody
1100%
+ 2 programs with unclassified modality

Competitive Landscape

3 companies ranked by most advanced pipeline stage

H
HutchmedChina - Hong Kong
1 program
1
HMPL-453Phase 2/31 trial
Active Trials
NCT04353375Recruiting235Est. Feb 2030
Varian Medical Systems
1 program
1
DurvalumabPhase 2Monoclonal Antibody
Virogin Biotech
Virogin BiotechBC - Richmond
1 program
1
Recombinant Human IL12/15-PDL1B Oncolytic HSV-1 InjectionPhase 21 trial
Active Trials
NCT06746480RecruitingEst. Dec 2025

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
2028
2029
2030
HutchmedHMPL-453
Virogin BiotechRecombinant Human IL12/15-PDL1B Oncolytic HSV-1 Injection

Clinical Trials (2)

Total enrollment: 235 patients across 2 trials

NCT04353375HutchmedHMPL-453

HMPL-453 Tartrate in Advanced Intrahepatic Cholangiocarcinoma

Start: Sep 2020Est. completion: Feb 2030235 patients
Phase 2/3Recruiting
NCT06746480Virogin BiotechRecombinant Human IL12/15-PDL1B Oncolytic HSV-1 Injection

Clinical Study of VG161 in Advanced Intrahepatic Cholangiocarcinoma

Start: Mar 2022Est. completion: Dec 2025
Phase 2Recruiting

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Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

2 actively recruiting trials targeting 235 patients
3 companies competing in this space

Related Indications

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