SPARK Biopharma

Korea - SeoulPharmaceutical2 H-1B visas (FY2023)

Focus: SPARK Biopharma is a Seoul-based pharmaceutical company specializing in small molecules across rare diseases, neurology, ophthalmology, oncology, and respiratory indications. The company operates with a lean active hiring footprint (4 open roles) and limited public financial disclosure.

Rare Diseases Neurology Ophthalmology Oncology

Profile data last refreshed 7h ago · AI intelligence enriched 1w ago

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Should You Work at SPARK Biopharma?

AI assessment

SPARK is a specialty biotech with meaningful rare disease and gene therapy programs, but limited hiring, unclear financials, and modest immigration track record make it a higher-risk career move for most candidates.

Why Work Here

Access to rare disease and gene therapy programs including Phase 3 gene therapy candidates (voretigene neparvovec-rzyl for inherited retinal dystrophy, SPK-8011 for Hemophilia A)

Data completeness

2/9 — Limited

Company HealthStrong

Pipeline

Mid-stage

2 Phase 3+

LOE Risk

Protected

No near-term cliffs

Hiring

Stable

Automated analysis based on publicly available data (FDA, SEC, ClinicalTrials.gov). May be incomplete or delayed. This score does not reflect insider knowledge and should not be used as the sole basis for investment or employment decisions.

Pipeline & Clinical Trials

Clinical Outcomes and Questionnaires

Opioid Use Disorder

N/A

Clinical Trials (1)

NCT05591703Clinical Outcomes Following Transcutaneous Auricular Neurostimulation to Improve Relapse Prevention: A Long-term Follow-up Study

N/A

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Data Sources

Drug label: DailyMed / FDA
Clinical trials: ClinicalTrials.gov
Patent data: FDA Orange Book
Spending data: CMS Medicare

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.

Small-molecule pipeline in early phases (SB17170 in Phase 1/2 across oncology and IPF) positioned for clinical advancement

International pharma exposure with Seoul headquarters, offering non-US career trajectory in specialty biotech

Watch Out For

Minimal hiring activity (4 active roles, concentrated in Customer Service and Supply Chain) signals limited growth or restructuring phase
H1B sponsorship challenges with 2 approvals and 1 denial in 2023, suggesting potential visa barriers for international talent
No disclosed revenue, cash position, or R&D spend creates visibility gap on financial stability and long-term runway

Generated by Claude from SPARK Biopharma's SEC filings, pipeline programs, hiring velocity, FDA actions, and WARN data. Inference, not editorial — verify before quoting.

Sparrow Fledging Therapy System

Neonatal Opioid Withdrawal Syndrome

N/A

Clinical Trials (1)

NCT05129020Neurostimulation to Improve NOWS Outcomes

N/A

HCFWO

Chronic Obstructive Pulmonary Disease

N/A

Clinical Trials (1)

NCT04654481Study of AffloVest in At-Risk Respiratory Patients During COVID-19 Pandemic

N/A

Sparrow Ascent

Alcohol Use Disorder

N/A

Clinical Trials (1)

NCT07281261tAN for Substance Use Disorder

N/A

Spark Biomedical Roo Transcutaneous Auricular Neurostimulation

Neonatal Abstinence Syndrome

N/A

Clinical Trials (1)

NCT04588519tAN to Mitigate Withdrawal Behaviors in Neonates

N/A

Neutralizing Antibody to SPK-3006 capsid

Pompe Disease

N/A

Clinical Trials (1)

NCT03893240Neutralizing Antibody Seroprevalence Study With a Retrospective Component in Participants With Late-Onset Pompe Disease

N/A

SPK-8011

Hemophilia A

N/A

Clinical Trials (1)

NCT03432520Long-Term Safety and Efficacy of Spark-Sponsored Gene Therapies in Males With Hemophilia A

N/A

Sparrow Link

Mental Fatigue

N/A

Clinical Trials (1)

NCT07109349tAN for First Responders

N/A

Volta System

Hemostasis

N/A

Clinical Trials (1)

NCT05977946Delivering Transcutaneous Auricular Neurostimulation to Regulate Platelet Activity in Healthy Human Subjects

N/A

Standard of Care FVIII Replacement therapy

Blood Coagulation Disorder

N/A

Clinical Trials (1)

NCT03876301Lead-in Study to Collect Prospective Efficacy and Safety Data of Current FVIII Prophylaxis Replacement Therapy in Adult Hemophilia A Participants

N/A

Volta tAN System

Blood Loss, Surgical

N/A

Clinical Trials (1)

NCT06647017Delivering Transcutaneous Auricular Neurostimulation to Reduce Blood Loss During Dialysis AV Graft Placement Procedures

N/A

Sparrow Hawk

Acute Stress Reaction

N/A

Clinical Trials (1)

NCT06390267Effect of Transcutaneous Auricular Neurostimulation on Cognitive Performance in a Laboratory Model of Acute Stress Reaction

N/A

Sparrow Ascent tAN

Posttraumatic Stress Disorder

N/A

Clinical Trials (1)

NCT06130501tAN for PTSD and OUD in Buprenorphine Therapy

N/A

EEG Diagnostic for Repetitive Sub-concussive Head Impacts

Concussion

N/A

Clinical Trials (1)

NCT05562544EEG Diagnostic for Repetitive Sub-concussive Head Impacts

N/A

AAV2-hRPE65v2,voretigene neparvovec-rzyl

Confirmed Biallelic RPE65 Mutation-associated Retinal Dystrophy

N/A

Clinical Trials (1)

NCT03597399A Patient Registry Study for Patients Treated With Voretigene Neparvovec in US

N/A

SPARK Test

Alzheimer Disease

N/A

Clinical Trials (1)

NCT05406778The REMIND Study- SPARK Neuro Software Study

N/A

TempTraq

Hematologic Malignancy

N/A

Clinical Trials (1)

NCT06415656VitalTraq for the Detection of CRS

N/A

Systems Medicine to Study Necrotizing Soft Tissue Infections (NSTIs).

Soft Tissue Infections

N/A

Clinical Trials (1)

NCT01790698Systems Medicine to Study Necrotizing Soft Tissue Infections (NSTIs).

N/A

Active Neurostimulation

Healthy

N/A

Clinical Trials (1)

NCT06782360Cognitive Augmentation Via Multimodal Sensing and Auricular Neurostimulation

N/A

Development of an EEG Diagnostic for Alzheimer's Disease

Mild Cognitive Impairment

N/A

Clinical Trials (1)

NCT04954183Development of an EEG Diagnostic for Alzheimer's Disease

N/A

Individually Tailored Perioperative Psychological Intervention

Breast Cancer

N/A

Clinical Trials (1)

NCT07510997Perioperative Individually Tailored Psychological Intervention in Breast Cancer Surgery

N/A

LTFU for Gene Transfer Subjects With Hemophilia B

Hemophilia B

N/A

Clinical Trials (1)

NCT00515710LTFU for Gene Transfer Subjects With Hemophilia B

N/A

SPARK Cognitive Status Indicator

Alzheimer Disease

N/A

Clinical Trials (1)

NCT06809725Software Validation Study-Cognitive Status Indicator

N/A

Sparrow Therapy System

Opioid-use Disorder

N/A

Clinical Trials (1)

NCT04731935Novel Earpiece for Transcutaneous Auricular Neurostimulation (tAN) for Symptoms of Opioid Withdrawal

N/A

TempTraq

Temperature

N/A

Clinical Trials (1)

NCT03264833Accuracy and Precision Comparison of Temptraq

N/A

Volta System

Heavy Menstrual Bleeding

N/A

Clinical Trials (1)

NCT06814028Transcutaneous Auricular Neurostimulation as a Treatment for Women With Heavy Menstrual Bleeding: A Dose-finding Trial

N/A

Sparrow Link

Heavy Menstrual Bleeding

N/A

Clinical Trials (1)

NCT07326722Delivering tAN to Reduce HMB: The LUNA Study

N/A

EmbracePlus Smartwatch

Opioid Withdrawal

N/A

Clinical Trials (1)

NCT06487533Sensing Physiological Symptoms of Opioid Withdrawal and Cravings in Patients With Opioid Use Disorder

N/A

transcutaneous auricular neurostimulation

Opioid-use Disorder

N/A

Clinical Trials (2)

NCT04075214Transcutaneous Auricular Neurostimulation (tAN) for Symptoms of Opioid Withdrawal

N/A

NCT07688720Transcutaneous Auricular Neurostimulation (tAN) for Premenstrual Dysphoric Disorder (PMDD) and Perimenopause

N/A

Volta System

Von Willebrand Disease, Type 1

N/A

Clinical Trials (1)

NCT06064851Delivering Transcutaneous Auricular Neurostimulation to Reduce Heavy Menstrual Bleeding in Patients With and Without Von Willebrand Disease

N/A

Sparrow Ascent Therapy System

Opioid-use Disorder

N/A

Clinical Trials (1)

NCT05053503Delivering Transcutaneous Auricular Neurostimulation to Improve Relapse Prevention in Opioid Use Disorder

N/A

SB17170

Safety Issues

Phase 1

Clinical Trials (1)

NCT05795192SB17170 Phase1 Trial in Healthy Volunteer