Glaukos(GKOS)
ALISO VIEJO, CA
BiotechnologyFocus: Glaucoma Devices
Glaukos is a life sciences company focused on Glaucoma Devices.
Ophthalmology
Funding Stage
PUBLIC
Open Jobs
0
Products & Portfolio (5)
EPIOXA HD/EPIOXA KIT
riboflavin 5-phosphate ophthalmic
LOE Approaching
OPHTHALMIC · SOLUTION/DROPS
5'-phosphate sodium (Vitamin B2) is the precursor of two coenzymes, flavin adenine dinucleotide and flavin mononucleotide, which catalyze oxidation/reduction reactions involved in a number of metabolic pathways. Under the conditions used for corneal collagen cross-linking, riboflavin 5'-phosphate functions as a photoenhancer and generates singlet oxygen which is responsible for the cross-linking.
2025
25
IDOSE TR
travoprost intracameral
Growth
INTRACAMERAL · IMPLANT
acid, a prostaglandin analog is a selective FP prostanoid receptor agonist, which is believed to reduce IOP by increasing uveoscleral outflow. The exact mechanism of action is unknown at this time.
intraocular pressure (IOP) in patients with open-angle glaucoma (OAG)ocular hypertension (OHT)ocular hypertension (OHT) ()+1 more
2023
8
MITOSOL
mitomycin
Peak
TOPICAL · FOR SOLUTION
(DNA). The guanine and cytosine content correlates with the degree of mitomycin-induced cross-linking. Cellular RNA and protein synthesis may also be suppressed.
2012
8
PHOTREXA VISCOUS IN DEXTRAN 20%
riboflavin 5-phosphate ophthalmic
Peak
OPHTHALMIC · SOLUTION/DROPS
5'-phosphate sodium (Vitamin B2) is the precursor of two coenzymes, flavin adenine dinucleotide and flavin mononucleotide, which catalyze oxidation/reduction reactions involved in a number of metabolic pathways. Under the conditions used for corneal collagen cross-linking, riboflavin 5'-phosphate functions as a photoenhancer and generates singlet oxygen which is responsible for the cross-linking.
2016
30
PHOTREXA VISCOUS IN DEXTRAN 20%/PHOTREXA
riboflavin 5-phosphate ophthalmic
Peak
OPHTHALMIC · SOLUTION/DROPS
5'-phosphate sodium (Vitamin B2) is the precursor of two coenzymes, flavin adenine dinucleotide and flavin mononucleotide, which catalyze oxidation/reduction reactions involved in a number of metabolic pathways. Under the conditions used for corneal collagen cross-linking, riboflavin 5'-phosphate functions as a photoenhancer and generates singlet oxygen which is responsible for the cross-linking.
2016
30
Pipeline & Clinical Trials
One iStent
Open-angle GlaucomaClinical Trials (1)
NCT01455467Open-angle Glaucoma Subjects on One Topical Hypotensive Medication Randomized to Treatment With One or Two Trabecular Micro-bypass Stents in Conjunction With Cataract Surgery
N/AEpi-on PiXL in high oxygen
KeratoconusClinical Trials (1)
NCT04668924Epi-on PiXL for the Treatment of Progressive Keratoconus.
N/AiStent Infinite
GlaucomaClinical Trials (1)
NCT05127551Clinical Study of Glaukos® Trabecular Micro-Bypass System Model iS3 Infinite Vs. Competitor
N/AGlaukos iStent inject®
Glaucoma, Open-AngleClinical Trials (1)
NCT03624699Investigation of the iStent Inject® Devices in Open-Angle Glaucoma
N/AVedera KXS
KeratoconusClinical Trials (1)
NCT01069848Feasibility Study of the Vedera KXS for Treatment of Keratoconus
N/ACataract surgery plus one iStent and one iStent Supra implanted
Glaucoma, Open-AngleClinical Trials (1)
NCT03255785Open-Angle Glaucoma Subjects With Cataract Treated With Cataract Surgery Plus One iStent and One iStent Supra
N/APost-approval Study of The Glaukos® iStent® Trabecular Micro-bypass Stent: Extended Follow-up of the
Primary Open Angle GlaucomaClinical Trials (1)
NCT01836042Post-approval Study of The Glaukos® iStent® Trabecular Micro-bypass Stent: Extended Follow-up of the Premarket Cohort
N/AN/A
Clinical Trials (1)
NCT01841450Multicenter Post-Approval Study Of The Glaukos® iStent® Trabecular Micro-Bypass Stent System In Conjunction With Cataract Surgery
N/AN/A
Clinical Trials (1)
NCT02327312Multicenter Investigation of Trabecular Micro-Bypass Stents vs. Laser Trabeculoplasty
N/A4.0 mm treatment
MyopiaClinical Trials (1)
NCT03987880Photorefractive Intrastromal Corneal Crosslinking as a Treatment for Low Grade Myopia
N/AiStent supra
Primary Open-angle GlaucomaClinical Trials (1)
NCT01461278Multicenter Investigation of the Glaukos® Suprachoroidal Stent Model G3 In Conjunction With Cataract Surgery
N/AiStent and iStent supra
Open-Angle GlaucomaClinical Trials (1)
NCT01456390Open-Angle Glaucoma Subjects With One Prior Trabeculectomy Treated Concurrently With One Suprachoroidal Stent and Two Trabecular Micro-bypass Stents
N/AN/A
Clinical Trials (1)
NCT01252849Purpose of This Study is to Evaluate the Safety and Efficacy of One, Two, or Three iStents for the Reduction of Intraocular Pressure in Open-angle Glaucoma Subjects
N/AiStent Inject Implantation
Glaucoma, Open-AngleClinical Trials (1)
NCT04624698iStent Inject New Enrollment Post-Approval Study
N/AiStent inject
Primary Open-angle GlaucomaClinical Trials (1)
NCT01461291Multicenter Study Using Glaukos® Trabecular Micro-Bypass Stent Model GTS400 Using the G2-M-IS Injector System in Conjunction With Cataract Surgery
N/ACXL Myopia
MyopiaClinical Trials (1)
NCT02872766Evaluation of the Safety and Efficacy of Corneal Cross Linking for the Treatment of Myopia.
N/AiStent inject surgery
Primary Open Angle Glaucoma (POAG)Clinical Trials (1)
NCT03478293iStent Inject in OAG Subjects on 2 Pre-op Topical Ocular Hypotensive Medications
N/AG2 and G3
Glaucoma, Open-AngleClinical Trials (1)
NCT03255798A Prospective Evaluation of Glaucoma Subjects Treated With Two Second Generation iStents and One iStent Supra
N/AVedera KXS
MyopiaClinical Trials (1)
NCT00925041Clinical Evaluation of the Vedera KXS for the Treatment of Spherical Myopia
N/AiStent Inject Trabecular Micro-Bypass System Continuation Post-Approval Study
Glaucoma, Open-AngleClinical Trials (1)
NCT04624685iStent Inject Trabecular Micro-Bypass System Continuation Post-Approval Study
N/APiXL
MyopiaClinical Trials (1)
NCT04663048PiXL as a Treatment for Low Grade Myopia
N/AiStent inject®
Glaucoma, Open-AngleClinical Trials (1)
NCT03106181A Comparison of Cataract Surgery Alone and Cataract Surgery With iStent
N/AN/A
Clinical Trials (1)
NCT01841437Glaukos® iStent® Trabecular Micro-Bypass Stent System In Conjunction With Cataract Surgery Postmarket Registry
N/AiStent Infinite
GlaucomaClinical Trials (1)
NCT06057051Glaukos® iStent Infinite Trabecular Micro-Bypass System in Subjects With Mild to Moderate Primary Open-angle Glaucoma
N/APiXL
MyopiaClinical Trials (1)
NCT03197272Advanced Cross Linking for Low-grade Myopia
N/AN/A
Clinical Trials (1)
NCT01517477One, Two, or Three iStents for the Reduction of Intraocular Pressure in Open-angle Glaucoma Subjects
N/AGlaucoma Surgery
Open-Angle GlaucomaClinical Trials (1)
NCT00326066A Study of the iStent in Combo With Cataract Surgery in Newly Diagnosed Open Angle Glaucoma or OH Patients.
N/AiStent
Open-angle GlaucomaClinical Trials (1)
NCT01444105Open-angle Glaucoma Subjects on One Ocular Hypotensive Medication Randomized to Treatment With Two Trabecular Micro-bypass Stents or Selective Laser Trabeculoplasty
N/AEpi-on PiXL
KeratoconusClinical Trials (1)
NCT03990506Photorefractive Intrastromal Crosslinking (PiXL) for the Treatment of Progressive Keratoconus
N/AMonitoring with contact lens sensor
Glaucoma EyeClinical Trials (1)
NCT06607705Changes in Eye Pressure in Glaucoma Patients Treated with Istent Inject W, Monitored by a Contact Lens Sensor
N/ATravoprost
Open Angle Glaucoma (OAG)Clinical Trials (1)
NCT07400926Observational Trial of the Updated Inserter for the Travoprost Intracameral Implant 75mcg
N/ALasikXtra
MyopiaClinical Trials (1)
NCT03913338Laser In-situ Keratomileusis With Crosslinking Compared to Conventional LASIK in Patients With High Myopia
N/ACorneal Collagen Cross-linking
Corneal EctasiaClinical Trials (1)
NCT03319082Observational Registry to Assess the Durability of Effect of CXL in Patients With Corneal Ectasia After Refractive Surgery
N/AModel iS3 three-stent trabecular micro-bypass system
GlaucomaClinical Trials (1)
NCT03639870Investigation of the Glaukos® Trabecular Micro-Bypass System, Model iS3, in Subjects With Refractory Glaucoma
N/Ariboflavin ophthalmic solution, 0% dextran
HyperopiaClinical Trials (1)
NCT01893359Safety and Efficacy of Corneal Collagen Cross-linking Following LASIK for Treatment of Hyperopia and Hyperopic Astigmatism
Phase 1/2NXL Energy 1
Progressive KeratoconusClinical Trials (1)
NCT05314738Safety and Efficacy of Corneal Cross-linking in Subjects With Keratoconus
Phase 1/2Pilocarpine Ophthalmic Topical Cream, Dose 1
PresbyopiaClinical Trials (1)
NCT05124275Safety and Efficacy of Pilocarpine Ophthalmic Topical Cream for the Treatment of Presbyopia
Phase 2Travoprost Intraocular Implant, high elution
Glaucoma Open-angleClinical Trials (1)
NCT02754596Study Comparing Travoprost Intraocular Implants to Timolol Ophthalmic Solution
Phase 2GLK-321 low dose BID
Demodex BlepharitisClinical Trials (1)
NCT07400965Evaluation of the Safety and Efficacy of GLK-321 in Subjects With Demodex Blepharitis
Phase 2Pilocarpine Ophthalmic Topical Cream, Dose 1
Dry Eye DiseaseClinical Trials (1)
NCT05119920Safety and Efficacy of Pilocarpine Ophthalmic Topical Cream for the Treatment of Dry Eye Disease
Phase 2GLK-221 Ophthalmic Solution
KeratoconusClinical Trials (1)
NCT07400952Placebo-controlled Study to Evaluate the Safety and Efficacy of GLK-221 Ophthalmic Solution in Subjects With Keratoconus
Phase 2Travoprost Ophthalmic Topical Cream low-dose
Open Angle GlaucomaClinical Trials (1)
NCT06152861Travoprost Ophthalmic Topical Cream for Open-angle Glaucoma or Ocular Hypertension
Phase 2Travoprost Intracameral Implant exchanged at Month 12
Glaucoma, Open-AngleClinical Trials (1)
NCT06582732Performance of the Travoprost Intraocular Implant
Phase 2Phase 2
lufepirsen high dose
Persistent Corneal Epithelial DefectClinical Trials (1)
NCT05966493A Study to Evaluate the Safety and Efficacy of NEXAGON® (Lufepirsen Ophthalmic Gel) in Subjects With PCED
Phase 2Travoprost
Open Angle GlaucomaClinical Trials (1)
NCT04615403Study of Exchange of Travoprost Intraocular Implant
Phase 2Gen 2 Travoprost Intracameral Implant
GlaucomaClinical Trials (1)
NCT07075718Phase 2/Phase 3 Trial to Evaluate the Safety and Efficacy of the Second Generation Travoprost Intracameral Implant
Phase 2/3G2-TR intraocular implant containing travoprost
Glaucoma, Open-AngleClinical Trials (1)
NCT03868124Clinical Study Comparing Two Models of a Travoprost Intraocular Implant
Phase 3Glaucoma Stent Surgery
Open-angle GlaucomaClinical Trials (1)
NCT00721968Safety and Efficacy of the GTS400 Stent in Conjunction With Cataract
Phase 3riboflavin solution
KeratoconusClinical Trials (1)
NCT01344187Safety and Efficacy Study of Corneal Collagen Cross-Linking in Eyes With Keratoconus
Phase 3Open Jobs (0)
No open positions listed yet. Check their careers page directly.
Interview Prep Quick Facts
Portfolio: 5 approved products, 49 clinical trials
Top TAs: Cardiovascular, Ophthalmology
SEC Filings: 2 available
Portfolio Health
Growth1 (20%)
Peak3 (60%)
LOE Approaching1 (20%)
5 total products
Financials (FY2025)
Revenue
$315M11%
R&D Spend
$139M(44%)13%
Net Income
-$135MCash
$93M