PHOTREXA VISCOUS IN DEXTRAN 20%

Peak

riboflavin 5-phosphate ophthalmic

NDAOPHTHALMICSOLUTION/DROPSPriority Review
Approved
Apr 2016
Lifecycle
Peak
Competitive Pressure
30/100

Mechanism of Action

5'-phosphate sodium (Vitamin B2) is the precursor of two coenzymes, flavin adenine dinucleotide and flavin mononucleotide, which catalyze oxidation/reduction reactions involved in a number of metabolic pathways. Under the conditions used for corneal collagen cross-linking, riboflavin 5'-phosphate…