Primary Open Angle Glaucoma (POAG)

Ophthalmology
1
Pipeline Programs
3
Companies
11
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
1
0
0
0
0
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

3 companies ranked by most advanced pipeline stage

Pfizer
PfizerNEW YORK, NY
1 program
1
LatanoprostPhase 15 trials
Active Trials
NCT01180062TerminatedEst. Jun 2014
NCT00934089Completed31Est. Jun 2010
NCT00716859Completed139Est. Nov 2009
+2 more trials
Alcon
AlconFORT WORTH, TX
2 programs
CyPass Micro-StentN/A1 trial
PerimetryN/A1 trial
Active Trials
NCT01166659CompletedEst. May 2014
NCT00902109UnknownEst. Dec 2016
Glaukos
GlaukosALISO VIEJO, CA
2 programs
iStentN/A1 trial
iStentN/A1 trial
Active Trials
NCT01252849CompletedEst. Oct 2019
NCT01517477CompletedEst. Oct 2019

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
PfizerLatanoprost
PfizerLatanoprost
PfizerLatanoprost
PfizerLatanoprost
PfizerLatanoprost
PfizerLatanoprost
GlaukosiStent
GlaukosiStent
AlconPerimetry
AlconCyPass Micro-Stent
PfizerLatanoprost

Clinical Trials (11)

Total enrollment: 1,537 patients across 11 trials

Effect of Age on Latanoprost 0.005% in Patients With Glaucoma

Start: Mar 2005Est. completion: Apr 200917 patients
Phase 4Completed

A Phase 3 Prospective, Randomized, Double-Masked, 12-Week, Parallel Group Study In Pediatric Subjects With Glaucoma.

Start: Jul 2008Est. completion: Nov 2009139 patients
Phase 3Completed

A Study of Glaucoma or Ocular Hypertension in Patients Within the United States

Start: Jul 1997Est. completion: Jun 1999418 patients
Phase 3Completed

A Phase 2 Study Of The 24-Hour Intraocular Pressure Lowering And Systemic Exposure Of PF-04217329

Start: Jan 2010Est. completion: Jun 201031 patients
Phase 2Completed

Circadian Rhythms of Aqueous Humor Dynamics in Humans

Start: Mar 2006Est. completion: Nov 200930 patients
Phase 2Completed

Safety Study of Latanoprost Slow Release Insert

Start: Jan 2011Est. completion: Jun 2014
Phase 1Terminated

One, Two, or Three iStents for the Reduction of Intraocular Pressure in Open-angle Glaucoma Subjects

Start: Jan 2012Est. completion: Oct 2019
N/ACompleted

Purpose of This Study is to Evaluate the Safety and Efficacy of One, Two, or Three iStents for the Reduction of Intraocular Pressure in Open-angle Glaucoma Subjects

Start: Dec 2010Est. completion: Oct 2019
N/ACompleted

Study to Compare Standard Perimetry With the New Scotoma-Oriented Perimetry (SCOPE) Using a New Fast German Adaptive Threshold Estimation (GATE) in Glaucoma Patients

Start: Apr 2010Est. completion: Dec 2016
N/AUnknown
NCT01166659AlconCyPass Micro-Stent

Study of CyPass Implantation In Patients With Open Angle Glaucoma Refractory to Single or Multi-agent Topical Therapy

Start: Feb 2010Est. completion: May 2014
N/ACompleted

Observational Study of the Long-term Effect of Latanoprost in Normal Tension Glaucoma

Start: Aug 2006Est. completion: Sep 2009902 patients
N/ACompleted

Related Jobs in Ophthalmology

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

3 companies competing in this space