Wet Age-Related Macular Degeneration

Ophthalmology
5
Pipeline Programs
3
Companies
3
Clinical Trials
2
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
2
0
0
0
1
2
Early DiscoveryClinical DevelopmentMarket

On Market (2)

Approved therapies currently available

Regeneron
EYLEAApproved
aflibercept
Regeneron
Vascular Endothelial Growth Factor Inhibitor [EPC]injection2011
Regeneron
EYLEA HDApproved
aflibercept
Regeneron
Vascular Endothelial Growth Factor Inhibitor [EPC]injection2023

Competitive Landscape

3 companies ranked by most advanced pipeline stage

Regeneron
RegeneronTARRYTOWN, NY
2 programs
1
AfliberceptN/A
AfliberceptN/A
Qilu Pharmaceutical
Qilu PharmaceuticalChina - Jinan
2 programs
1
1
AfliberceptPhase 31 trial
lucentisPhase 11 trial
Active Trials
NCT03312283CompletedEst. Apr 2019
NCT05345236CompletedEst. Jan 2022
Molecular Partners
Molecular PartnersSchlieren-Zurich, Switzerland
1 program
1
MP0112Phase 11 trial
Active Trials
NCT01086761Terminated32Est. Nov 2010

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
Qilu PharmaceuticalAflibercept
Qilu Pharmaceuticallucentis
Molecular PartnersMP0112

Clinical Trials (3)

Total enrollment: 32 patients across 3 trials

A Study to Compare QL1207 to Eylea® in Subjects With Wet Age-related Macular Degeneration (wAMD)

Start: Aug 2019Est. completion: Jan 2022
Phase 3Completed

Evaluating of the Safety, Pharmacokinetics and Pharmacodynamics of QL1205 and Lucentis® in Patients With Wet AMD

Start: Dec 2017Est. completion: Apr 2019
Phase 1Completed

Study of MP0112 Intravitreal Injection in Patients With Wet Age Related Macular Degeneration

Start: Mar 2010Est. completion: Nov 201032 patients
Phase 1Terminated

Related Jobs in Ophthalmology

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

1 late-stage (Phase 3) programs — potential near-term approvals
3 companies competing in this space