Upper Gastrointestinal Bleeding
Gastroenterology
1
Pipeline Programs
3
Companies
3
Clinical Trials
0
Approved Products
Pipeline by Development Stage
Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
0
0
1
0
Early DiscoveryClinical DevelopmentMarket
Competitive Landscape
3 companies ranked by most advanced pipeline stage
Bausch HealthQUEBEC, Quebec, Canada
1 program1
Omeprazole sodium bicarbonate immediate release PWD/FSPhase 31 trial
Active Trials
Mission TherapeuticsUK - Cambridge
1 programRISK STRATIFICATION USING AIMS65 SCORE AND RDWN/A1 trial
Active Trials
AstraZenecaCAMBRIDGE, United Kingdom
1 programStudy of Incidence of Drug-induced Upper Gastrointestinal BleedingN/A1 trial
Active Trials
Trial Timeline
Clinical trial activity over time
2021
2022
2023
2024
2025
2026
Bausch HealthOmeprazole sodium bicarbonate immediate release PWD/FS
Mission TherapeuticsRISK STRATIFICATION USING AIMS65 SCORE AND RDW
AstraZenecaStudy of Incidence of Drug-induced Upper Gastrointestinal Bleeding
Clinical Trials (3)
Total enrollment: 648 patients across 3 trials
Safety & Efficacy of Omeprazole Sodium Bicarbonate for the Prevention of Upper GI Bleeding in the Critically Ill
Start: May 2002Est. completion: May 2003
Phase 3Completed
Risk Stratification of Patients Presenting With Upper Gastrointestinal Bleeding to the Emergency Department Using AIMS65 Score and Red Cell Distribution Width
Start: Aug 2018Est. completion: Oct 2020348 patients
N/ACompleted
Study of Incidence of Drug-induced Upper Gastrointestinal Bleeding
Start: Jun 2010Est. completion: Jun 2011300 patients
N/ACompleted
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Phase Legend
Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available
Key Insights
1 late-stage (Phase 3) programs — potential near-term approvals
3 companies competing in this space