Uncontrolled Hypertension

Cardiovascular
4
Pipeline Programs
3
Companies
4
Clinical Trials
1 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
2
0
2
0
0
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

3 companies ranked by most advanced pipeline stage

Regeneron
RegeneronTARRYTOWN, NY
1 program
1
REGN5381Phase 21 trial
Active Trials
NCT06833190Terminated34Est. Oct 2025
Retension Pharmaceuticals
Retension PharmaceuticalsVA - Falls Church
1 program
1
RTN-001Phase 21 trial
Active Trials
NCT07142356RecruitingEst. May 2027
Qilu Pharmaceutical
Qilu PharmaceuticalChina - Jinan
2 programs
2
QLS1410Phase 11 trial
QLS1410Phase 11 trial
Active Trials
NCT07152444Not Yet RecruitingEst. Jul 2026
NCT07358858Not Yet RecruitingEst. Feb 2026

Trial Timeline

Clinical trial activity over time

2025
2026
2027
Retension PharmaceuticalsRTN-001
RegeneronREGN5381
Qilu PharmaceuticalQLS1410
Qilu PharmaceuticalQLS1410

Clinical Trials (4)

Total enrollment: 34 patients across 4 trials

NCT07142356Retension PharmaceuticalsRTN-001

A Study of Modified Release RTN-001 In Patients With Uncontrolled Hypertension

Start: Oct 2025Est. completion: May 2027
Phase 2Recruiting
NCT06833190RegeneronREGN5381

REGN5381 in Adult Participants With Uncontrolled Hypertension

Start: Apr 2025Est. completion: Oct 202534 patients
Phase 2Terminated
NCT07358858Qilu PharmaceuticalQLS1410

A Food Effect Study of QLS1410 in Healthy Chinese Adults

Start: Jan 2026Est. completion: Feb 2026
Phase 1Not Yet Recruiting
NCT07152444Qilu PharmaceuticalQLS1410

A Phase I Trial of QLS1410 in Healthy Chinese Adults and Participants With Mild Essential Hypertension

Start: Sep 2025Est. completion: Jul 2026
Phase 1Not Yet Recruiting

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Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

1 actively recruiting trials targeting 34 patients
3 companies competing in this space

Related Indications

Heart Failure(334)Hypertension(333)Coronary Artery Disease(295)Atrial Fibrillation(288)Pulmonary Arterial Hypertension(103)Acute Coronary Syndrome(62)Pulmonary Hypertension(55)Essential Hypertension(32)Coronary Heart Disease(28)Aortic Valve Stenosis(27)