Tumor, Solid

Oncology
9
Pipeline Programs
7
Companies
11
Clinical Trials
2 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
5
2
2
0
0
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

7 companies ranked by most advanced pipeline stage

Eikon Therapeutics
Eikon TherapeuticsCA - Millbrae
4 programs
3
1
BDB001Phase 21 trial
BDB001Phase 11 trial
BDB001Phase 11 trial
BDB018Phase 11 trial
Active Trials
NCT03486301Completed87Est. Apr 2024
NCT04196530Completed40Est. Aug 2024
NCT04840394Completed1Est. Sep 2024
+1 more trials
Elios Therapeutics
1 program
1
Tumor lysate, particle onlyPhase 21 trial
Active Trials
NCT06175221TerminatedEst. Jul 2025
Leucid Bio
Leucid BioUK - London
1 program
1
LEU011Phase 1/21 trial
Active Trials
NCT06193902Recruiting17Est. May 2029
Evopoint Biosciences
Evopoint BiosciencesChina - Beijing
1 program
1
XNW29016Phase 1/21 trial
Active Trials
NCT06987500Recruiting132Est. Aug 2027
BridgeBio Pharma
BridgeBio PharmaCA - Palo Alto
1 program
1
BBP-398Phase 11 trial
Active Trials
NCT04528836Terminated72Est. Jul 2024
M&
Merck & Co.RAHWAY, NJ
1 program
1
MK-8353Phase 11 trial
Active Trials
NCT01358331Terminated25Est. May 2014
Siemens Healthineers
Siemens HealthineersGermany - Forchheim
2 programs
Proton Therapy SystemN/A1 trial
Radiation: Proton Therapy SystemN/A1 trial
Active Trials
NCT05463055CompletedEst. Nov 2022
NCT06340815CompletedEst. Mar 2023

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
2028
2029
Elios TherapeuticsTumor lysate, particle only
Eikon TherapeuticsBDB001
Evopoint BiosciencesXNW29016
Leucid BioLEU011
Eikon TherapeuticsBDB018
BridgeBio PharmaBBP-398
Eikon TherapeuticsBDB001
Eikon TherapeuticsBDB001
Merck & Co.MK-8353
Siemens HealthineersRadiation: Proton Therapy System
Siemens HealthineersProton Therapy System

Clinical Trials (11)

Total enrollment: 375 patients across 11 trials

NCT06175221Elios TherapeuticsTumor lysate, particle only

Autologous TLPO Vaccine Basket

Start: Nov 2023Est. completion: Jul 2025
Phase 2Terminated
NCT04819373Eikon TherapeuticsBDB001

BDB001-201: A Clinical Study of BDB001 in Patients With PD-(L)1 Refractory Solid Tumors

Start: Aug 2021Est. completion: May 20231 patients
Phase 2Completed
NCT06987500Evopoint BiosciencesXNW29016

A Study of PARG Inhibitor XNW29016 in Patients With Advanced Solid Tumors Who Failed Standard Treatment

Start: Apr 2025Est. completion: Aug 2027132 patients
Phase 1/2Recruiting
NCT06193902Leucid BioLEU011

LEU01101: Safety and Preliminary Efficacy of LEU011 in Solid Tumours.

Start: Nov 2023Est. completion: May 202917 patients
Phase 1/2Recruiting
NCT04840394Eikon TherapeuticsBDB018

Clinical Study of BDB018: Monotherapy and in Combination With Pembrolizumab in Subjects With Advanced Solid Tumors

Start: Jun 2021Est. completion: Sep 20241 patients
Phase 1Completed
NCT04528836BridgeBio PharmaBBP-398

First-in-Human Study of the SHP2 Inhibitor BBP-398 in Patients With Advanced Solid Tumors

Start: Nov 2020Est. completion: Jul 202472 patients
Phase 1Terminated
NCT04196530Eikon TherapeuticsBDB001

BDB001-102: Open Label Dose Escalation of BDB001 in Combination w Atezolizumab

Start: Nov 2019Est. completion: Aug 202440 patients
Phase 1Completed
NCT03486301Eikon TherapeuticsBDB001

BDB001-101: Clinical Study of BDB001 as a Mono-therapy or in Combination With Pembrolizumab

Start: Feb 2018Est. completion: Apr 202487 patients
Phase 1Completed
NCT01358331Merck & Co.MK-8353

A Study of the Safety, Tolerability, and Efficacy of MK-8353 in Participants With Advanced Solid Tumors (MK-8353-001)

Start: Nov 2011Est. completion: May 201425 patients
Phase 1Terminated
NCT06340815Siemens HealthineersRadiation: Proton Therapy System

Varian ProBeam Proton Therapy System Clinical Trial (Shandong)

Start: Jul 2022Est. completion: Mar 2023
N/ACompleted
NCT05463055Siemens HealthineersProton Therapy System

Varian ProBeam Proton Therapy System China Clinical Trial (Hefei)

Start: Dec 2021Est. completion: Nov 2022
N/ACompleted

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Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

2 actively recruiting trials targeting 375 patients
7 companies competing in this space

Related Indications

Breast Cancer(530)Non-small Cell Lung Cancer(373)Prostate Cancer(371)Multiple Myeloma(244)Advanced Solid Tumors(221)Acute Myeloid Leukemia(204)Cancer(187)Neoplasms(173)Colorectal Cancer(166)Advanced Solid Tumor(165)