Transthyretin (TTR) Amyloid Cardiomyopathy

Cardiovascular
0
Pipeline Programs
2
Companies
2
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
0
0
0
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

2 companies ranked by most advanced pipeline stage

BridgeBio Pharma
BridgeBio PharmaCA - Palo Alto
1 program
AI Toolkit for ATTR-CM DiagnosisN/A1 trial
Active Trials
NCT07062848Active Not Recruiting1,500,000Est. Jan 2027
Pfizer
PfizerNEW YORK, NY
1 program
Treatment for TTR amyloidosisN/A1 trial
Active Trials
NCT04108091Completed1,214Est. Mar 2025

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
BridgeBio PharmaAI Toolkit for ATTR-CM Diagnosis
PfizerTreatment for TTR amyloidosis

Clinical Trials (2)

Total enrollment: 1,501,214 patients across 2 trials

NCT07062848BridgeBio PharmaAI Toolkit for ATTR-CM Diagnosis

An Observational Study Using Artificial Intelligence (AI) Algorithms on Electrocardiography (ECG), Point-of-care Ultrasound (POCUS), and Transthoracic Echocardiophy (TTE) to Estimate the Under-diagnosis of Transthyretin Amyloid Cardiomyopathy (ATTR-CM) Across a Diverse Range of US Health Systems.

Start: Jan 2025Est. completion: Jan 20271,500,000 patients
N/AActive Not Recruiting
NCT04108091PfizerTreatment for TTR amyloidosis

Vyndaqel Capsules Special Investigation (ATTR-CM)

Start: Oct 2019Est. completion: Mar 20251,214 patients
N/ACompleted

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Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

2 companies competing in this space

Related Indications

Heart Failure(334)Hypertension(333)Coronary Artery Disease(295)Atrial Fibrillation(288)Pulmonary Arterial Hypertension(103)Acute Coronary Syndrome(62)Pulmonary Hypertension(55)Essential Hypertension(32)Coronary Heart Disease(28)Aortic Valve Stenosis(27)