BRILINTA (ticagrelor) by AstraZeneca is p2y12 receptor antagonists [moa]. Approved for acute coronary syndrome, coronary artery disease, myocardial infarction and 1 more indications. First approved in 2011.
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BRILINTA (ticagrelor) is an oral P2Y12 platelet inhibitor approved by the FDA in July 2011 for reducing the risk of cardiovascular death, myocardial infarction, and stroke in patients with acute coronary syndrome (ACS), established coronary artery disease (CAD), or recent myocardial infarction. It works by irreversibly blocking the P2Y12 adenosine diphosphate receptor on platelets, preventing platelet aggregation. The drug is positioned as a key antiplatelet therapy for secondary prevention in high-risk cardiovascular and cerebrovascular patients, often used in combination with aspirin.
P2Y12 Receptor Antagonists
P2Y12 Platelet Inhibitor
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The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.
A Study to Investigate the Effect of Oral Ticagrelor on the Pharmacokinetics of Oral Rosuvastatin When Given in Healthy Participants
Ticagrelor Tablets 90 mg Relative to Originator Ticagrelor Tablets 90 mg
Ticagrelor De-escalation Strategy in AMI Patients
Disparities in the Proportion of Ticagrelor and Prasugrel-eligible Patients with Acute Coronary Syndrome in a Real-world Registry
A Study to Evaluate BMS-986141 Added on to Aspirin or Ticagrelor or the Combination, on Thrombus Formation in a Thrombosis Chamber Model in Participants With Stable Coronary Artery Disease and Healthy Participants
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BRILINTA supports approximately 50 currently open job positions across brand marketing, medical affairs, field sales, clinical specialists, and health outcomes roles. Key skill requirements include cardiovascular disease knowledge, clinical evidence synthesis for cardiologists and neurologists, payer management, and outcomes research in secondary prevention populations. Positions span commercial, medical, and market access functions within AstraZeneca's cardiovascular franchise.