Penumbra(PEN)

ALAMEDA, CAMedical Devices8 H-1B visas (FY2023)

Focus: Penumbra is a public medical device company specializing in minimally-invasive vascular and surgical devices for acute stroke, pulmonary embolism, and intracranial hemorrhage. The company operates at ~$1.1B in FY2025 revenue with strong recent growth and profitability.

Cardiovascular

Profile data last refreshed Yesterday · AI intelligence enriched 1w ago

Funding Stage

PUBLIC

Open Jobs

79-1 this month

Stable — net -1 jobs in 30d

29 added, 30 removed. Backfill posture.

Should You Work at Penumbra?

AI assessment

Best suited for commercial, operational, and manufacturing professionals seeking growth in a profitable, acquisition-target medical device company; limited appeal for pure research scientists.

Why Work Here

Strong revenue growth (30% YoY in FY2025) and return to profitability ($91M net income) signals financial stability and reinvestment capacity

Data completeness

4/9 — Basic

Company HealthStrong

Pipeline

Mid-stage

1 Phase 3+

LOE Risk

Protected

No near-term cliffs

Hiring

Stable

Revenue

$1.1B

Pipeline & Clinical Trials

Penumbra System

Stroke, Ischemic

N/A

Clinical Trials (1)

NCT04157270LOTUS: Global Acute Stroke Study Utilizing Penumbra System

N/A

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Data Sources

Drug label: DailyMed / FDA
Clinical trials: ClinicalTrials.gov
Patent data: FDA Orange Book
Spending data: CMS Medicare

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.

Heavy commercial hiring (35 of 80 active roles) indicates aggressive market expansion and sales career opportunities

Focused pipeline in high-acuity cardiovascular/neuro indications with established products (Penumbra System, Indigo Aspiration System) already generating revenue

Watch Out For

Low R&D intensity (8%) and device-heavy portfolio means limited scientific research career paths compared to pharma peers
Recent investor alert regarding proposed sale (April 2026) creates M&A uncertainty and potential organizational instability

Generated by Claude from Penumbra's SEC filings, pipeline programs, hiring velocity, FDA actions, and WARN data. Inference, not editorial — verify before quoting.

Automated analysis based on publicly available data (FDA, SEC, ClinicalTrials.gov). May be incomplete or delayed. This score does not reflect insider knowledge and should not be used as the sole basis for investment or employment decisions.

Penumbra System

Acute Ischemic Stroke

N/A

Clinical Trials (1)

NCT00963989Imaging Guided Patient Selection for Interventional Revascularization Therapy

N/A

Current standard of care for acute ischemic stroke other than IV rtPA or other IA therapies

Stroke

N/A

Clinical Trials (1)

NCT01092819A Clinical Trial to Assess the Acute Safety and Functional Outcome and Recovery After STROKE: The FIRST Trial

N/A

Penumbra System ®

Acute Ischemic Stroke (AIS)

N/A

Clinical Trials (1)

NCT07107022Study to Collect Real-world Performance and Safety Data on Penumbra System® in Population With Acute Ischemic Stroke (AIS).

N/A

Mechanical Thrombectomy

Acute Ischemic Stroke

N/A

Clinical Trials (1)

NCT05437055THUNDER: Acute Ischemic Stroke Study with the Penumbra System® Including Thunderbolt™ Aspiration Tubing

N/A

Indigo Aspiration System

Deep Vein Thrombosis

N/A

Clinical Trials (1)

NCT05003843BOLT: Study of the Indigo® Aspiration System When Used in Patients With Deep Vein Thrombosis

N/A

Artemis + Medical Management

Cerebral Hemorrhage

N/A

Clinical Trials (1)

NCT03342664MIND: Artemis in the Removal of Intracerebral Hemorrhage

N/A

Minimally-invasive endoscopy-guided surgery

Intracerebral Hemorrhage

N/A

Clinical Trials (1)

NCT03608423Dutch Intracerebral Hemorrhage Surgery Trial Pilot Study

N/A

Artemis Neuro Evacuation Device

Intracerebral Hemorrhage

N/A

Clinical Trials (1)

NCT04178746PRONTO: Artemis in the Removal of Intraventricular Hemorrhage in the Hyper-Acute Phase

N/A

PC 400

Intracranial Aneurysms

N/A

Clinical Trials (1)

NCT02122133CARE: A Prospective Multicenter Case Study to Assess Radiation Exposure in Patients Treated With the Penumbra Coil 400

N/A

Indigo Aspiration System

Lower Extremity Acute Limb Ischemia

N/A

Clinical Trials (1)

NCT04144959A Study of Patients With Lower Extremity Acute Limb Ischemia to Remove Thrombus With the Indigo Aspiration System

N/A

PC 400 coils

Intracranial Aneurysms

N/A

Clinical Trials (1)

NCT01465841Study of the Penumbra Coil 400 System to Treat Aneurysm

N/A

Indigo Aspiration System

Lower Extremity Acute Limb Ischemia

N/A

Clinical Trials (1)

NCT06747117A Study of Patients With Lower Extremity Acute Limb Ischemia to Remove Thrombus With the Indigo™ Aspiration System (STRIDE II)

N/A

WAVE, as part of the SMART COIL System

Aneurysm, Brain

N/A

Clinical Trials (1)

NCT04106583Assessing the WAVE Extra Soft Coil in Intracranial Aneurysms and Comparing Imaging Modalities

N/A

Splenic artery embolization with vascular embolic coils or plugs

High-grade Splenic Injuries

N/A

Clinical Trials (1)

NCT05128955Embolization of the Splenic Artery After Trauma

N/A

Stent assisted coiling with the Liberty Stent

Wide-neck, Saccular Intracranial Aneurysms

N/A

Clinical Trials (1)

NCT01636453The Penumbra Liberty Trial: Safety and Effectiveness in the Treatment of Wide-Neck Intracranial Aneurysms

N/A

Penumbra Smart Coil

Intracranial Aneurysm

N/A

Clinical Trials (1)

NCT02729740Assessment of the Embolization of Neurovascular Lesions Using the Penumbra Smart Coil

N/A

Indigo Aspiration System

Coronary Vessel Occlusion

N/A

Clinical Trials (1)

NCT03957473Study of the CAT RX Aspiration Catheter When Used in Patients With Large Occlusive Thrombus in Coronary Arteries

N/A

Mechanical aspiration thrombectomy

Acute Limb Ischemia

N/A

Clinical Trials (1)

NCT06446024Post Market Surveillance to Evaluate the Efficacy and Safety of the INDIGO Aspiration System in Japan

N/A

Mechanical Thrombectomy by the Indigo System

Peripheral Arterial Occlusion or Emboli

N/A

Clinical Trials (1)

NCT02085551Case Review of the Penumbra and Indigo Systems for Mechanical Thrombectomy in the Periphery

N/A

Minimally invasive endoscopy-guided surgery

Intracerebral Hemorrhage

N/A

Clinical Trials (1)

NCT05460793Dutch Intracerebral Hemorrhage Surgery Trial

N/A

PC 400 coils

Intracranial Aneurysms

N/A

Clinical Trials (1)

NCT01754051A Volumetric Coiling in Aneurysm Registry of the Penumbra Coil 400TM System

N/A

Penumbra System

Stroke, Ischemic

N/A

Clinical Trials (1)

NCT03464565COMPLETE: International Acute Ischemic Stroke Registry With the Penumbra System Aspiration Including the 3D Revascularization Device

N/A

Indigo Aspiration System

Pulmonary Embolism

N/A

Clinical Trials (1)

NCT04798261Study of the Long-Term Safety and Outcomes of Treating Pulmonary Embolism With the Indigo Aspiration System

N/A

Penumbra Aspiration System

Ischemic Stroke

N/A

Clinical Trials (1)

NCT02678169European Registry on the ACE Reperfusion Catheters and the Penumbra System in the Treatment of Acute Ischemic Stroke

N/A

Endovascular Therapy

Acute Ischemic Stroke

N/A

Penumbra System with Separator 3D

Acute Ischemic Stroke From Large Vessel Occlusion

N/A

Clinical Trials (1)

NCT01584609A Randomized, Concurrent Controlled Trial to Assess the Safety and Effectiveness of the Separator 3D as a Component of the Penumbra System in the Revascularization of Large Vessel Occlusion in Acute Ischemic Stroke

N/A

A Study of Survival and Outcome After Stroke

Ischemic Stroke

N/A

Clinical Trials (1)

NCT01193569A Study of Survival and Outcome After Stroke

N/A

Penumbra System

Stroke

N/A

Clinical Trials (1)

NCT00785161Penumbra Imaging Collaborative Study (PICS)

N/A

Anticoagulation

Pulmonary Embolism Acute

N/A

Clinical Trials (1)

NCT05684796Comparison of Two Pulmonary Embolism Treatments

N/A

Transcatheter Venography

Chronic Pelvic Pain Syndrome

N/A

Clinical Trials (1)

NCT06168058Trial of Ovarian Vein and Pelvic Vein Embolization in Women With Chronic Pelvic Pain and Pelvic Varices

N/A

Mechanical thrombectomy

Ischemic Stroke

N/A

Clinical Trials (1)

NCT04693767Investigation of Clot in Ischemic Stroke and Hematoma Evacuation

N/A

Indigo Aspiration System

Pulmonary Embolism

N/A

Clinical Trials (1)

NCT03218566Evaluating the Safety and Efficacy of the Indigo® Aspiration System in Acute Pulmonary Embolism

N/A

Thrombolysis in combination with endhole aspiration

Acute Deep Vein Thrombosis

N/A

Clinical Trials (1)

NCT04297787Safety and Efficacy of Thrombolysis in Combination With Endhole Aspiration in the Treatment of Acute DVT

N/A

Penumbra System

Stroke

PHASE_2

Clinical Trials (1)

NCT00334061Study to Assess the Safety and Effectiveness of the Penumbra System

Phase 2

Liberty Stent

Wide Neck Intracranial Aneurysms

PHASE_2

Clinical Trials (1)

NCT01753388Safety and Performance of the Penumbra Liberty Stent in the Treatment of Wide-Neck, Saccular, Intracranial Aneurysms

Phase 2

Thrombectomy

Stroke

PHASE_3

Penumbra Ruby Coil System

Visceral Artery Aneurysms

PHASE_4

Clinical Trials (1)

NCT02079818Visceral Artery Aneurysm Embolization by the Penumbra Ruby™ Coil System

Phase 4

intravenous

Ischemic Stroke

PHASE_4

Clinical Trials (1)

NCT01429350Assess the Penumbra System in the Treatment of Acute Stroke

Phase 4

Interview Prep Quick Facts

Portfolio: 37 clinical trials

Top TAs: Neurology, Cardiovascular, Respiratory

H-1B (2023): 8 approvals

SEC Filings: 2 available

Open Roles: 79 active jobs

Therapeutic Area Focus

Neurology

13 pipeline

Cardiovascular

3 pipeline

Respiratory

3 pipeline

Marketed

Pipeline

Financials (FY2025)

Revenue

$1.1B25%

R&D Spend

$84M(8%)6%

Net Income

$91M

Hiring Trend

Stable

Open Roles

Added

-5

Filled/Removed

Based on last 4 crawl cycles

Visa Sponsorship

Sponsors Work Visas

H-1B Petitions (FY2023)

Approved

Denied

100%

Rate

Source: USCIS H-1B Employer Data Hub

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Penumbra(PEN)

Should You Work at Penumbra?

Why Work Here

Pipeline & Clinical Trials

Watch Out For

Recent News · Penumbra(10)

Open Jobs (79)

Equipment Technician II

Marketing Operations High School Intern T

Quality Assurance Engineering Supervisor

Procurement Process Excellence Lead

Principal Quality Engineer

Quality Engineer I

Sr. R&D Engineer

IT Intern - Temp

IT Experience Services Systems Administrator

Manager of SAP BASIS and Security

Senior Clinical Budget Analyst

Manufacturing Engineer I - Metals

Associate Director, Operational Procurement

Manager, SAP Finance

Internal Communications Specialist

Global Project Manager, Marketing Content

OA&A Process Excellence Principal

Employment Counsel

QA Manager, Training Services

Manufacturing Engineer I – Electronics Development

Market Access Analytics Manager

Quality Engineer I

Senior Administrative Assistant, Finance

Senior Business Systems Analyst, CRM

R&D Engineer I

Financials (FY2025)

Hiring Trend

Visa Sponsorship