Prostate Adenocarcinoma

Oncology
6
Pipeline Programs
6
Companies
8
Clinical Trials
5 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
6
0
0
0
Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

Monoclonal Antibody
1100%
+ 6 programs with unclassified modality

Competitive Landscape

6 companies ranked by most advanced pipeline stage

Blue Earth Therapeutics
2 programs
2
FurosemidePhase 21 trial
Positron Emission TomographyPhase 21 trial
Active Trials
NCT05779943Active Not RecruitingEst. Jul 2028
NCT04175431RecruitingEst. Jul 2033
Arcus Biosciences
1 program
1
AtezolizumabPhase 2Monoclonal Antibody1 trial
Active Trials
NCT03821246Recruiting68Est. Apr 2026
Pfizer
PfizerNEW YORK, NY
1 program
1
Biospecimen CollectionPhase 22 trials
Active Trials
NCT06330805Recruiting70Est. Dec 2027
NCT05775471Recruiting21Est. Dec 2028
Novartis
NovartisBASEL, Switzerland
1 program
1
Lu-17-PSMA-617Phase 21 trial
Active Trials
NCT06798558Recruiting54Est. Mar 2029
Bavarian Nordic
Bavarian NordicDenmark - Kvistgard
1 program
1
MVA-BN-BrachyuryPhase 21 trial
Active Trials
NCT04020094Withdrawn0Est. Apr 2021
Alpha Tau Medical
Alpha Tau MedicalJERUSALEM, Israel
1 program
Radiation: Diffusing Alpha Radiation Emitters TherapyN/A1 trial
Active Trials
NCT04543903Completed1Est. Oct 2025

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
2028
2029
2030
2031
NovartisLu-17-PSMA-617
PfizerBiospecimen Collection
PfizerBiospecimen Collection
Blue Earth TherapeuticsFurosemide
Blue Earth TherapeuticsPositron Emission Tomography
Bavarian NordicMVA-BN-Brachyury
Arcus BiosciencesAtezolizumab
Alpha Tau MedicalRadiation: Diffusing Alpha Radiation Emitters Therapy

Clinical Trials (8)

Total enrollment: 214 patients across 8 trials

NCT06798558NovartisLu-17-PSMA-617

Neoadjuvant Lu-177-PSMA-617 in Patients With High Risk Localized Prostate Cancer Undergoing Radical Prostatectomy

Start: Mar 2025Est. completion: Mar 202954 patients
Phase 2Recruiting
NCT06330805PfizerBiospecimen Collection

Effects of Relugolix vs Leuprolide on Cardiac Function in Patients With Prostate Cancer

Start: Aug 2024Est. completion: Dec 202770 patients
Phase 2Recruiting
NCT05775471PfizerBiospecimen Collection

Pembrolizumab and Enfortumab Vedotin With Pembrolizumab Prior to and After Radical Nephroureterectomy for High-Risk Upper Tract Urothelial Cancer

Start: Jun 2024Est. completion: Dec 202821 patients
Phase 2Recruiting
NCT05779943Blue Earth TherapeuticsFurosemide

Comparison of 18F-rhPSMA-7.3 PET/CT With and Without Furosemide in Biochemical Recurrence of Prostate Cancer

Start: Apr 2023Est. completion: Jul 2028
Phase 2Active Not Recruiting
NCT04175431Blue Earth TherapeuticsPositron Emission Tomography

Prostate Specific Membrane Antigen (PSMA) or (FACBC) PET/CT Site-Directed Therapy for Treatment of Prostate Cancer, Flu-BLAST-PC Study

Start: Sep 2020Est. completion: Jul 2033
Phase 2Recruiting
NCT04020094Bavarian NordicMVA-BN-Brachyury

Perioperative Atezolizumab With MVA-BN-Brachyury and PROSTVAC For Intermediate-Risk And High-Risk Localized Prostate Cancer

Start: Nov 2019Est. completion: Apr 20210
Phase 2Withdrawn
NCT03821246Arcus BiosciencesAtezolizumab

Neoadjuvant Atezolizumab-Based Combination Therapy in Men With Localized Prostate Cancer Prior to Radical Prostatectomy

Start: Oct 2019Est. completion: Apr 202668 patients
Phase 2Recruiting
NCT04543903Alpha Tau MedicalRadiation: Diffusing Alpha Radiation Emitters Therapy

Neoadjuvant Interstitial Brachytherapy Using Diffusing Alpha Emitters Radiation Therapy in Men With Prostate Cancer

Start: May 2022Est. completion: Oct 20251 patients
N/ACompleted

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Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

5 actively recruiting trials targeting 214 patients
6 companies competing in this space

Related Indications

Breast Cancer(530)Non-small Cell Lung Cancer(373)Prostate Cancer(371)Multiple Myeloma(244)Advanced Solid Tumors(221)Acute Myeloid Leukemia(204)Cancer(187)Neoplasms(173)Colorectal Cancer(166)Advanced Solid Tumor(165)