Portal Hypertension

Cardiovascular
1
Pipeline Programs
3
Companies
50
Clinical Trials
4 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
1
0
0
0
0
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

3 companies ranked by most advanced pipeline stage

Ferring Pharmaceuticals
Ferring PharmaceuticalsArgentina - Buenos Aires
1 program
1
FE 204205Phase 11 trial
Active Trials
NCT02929407Terminated4Est. Sep 2017
Argon Medical Devices
2 programs
Scorpion Portal Vein Access KitN/A1 trial
Scorpion Portal Vein Access KitN/A1 trial
Active Trials
NCT06856655CompletedEst. Mar 2024
NCT05765253TerminatedEst. Nov 2023
Alliance Pharmaceuticals
1 program
CTN/A5 trials
Active Trials
NCT06160947Not Yet Recruiting24Est. Mar 2028
NCT07443826Recruiting12Est. Jun 2028
NCT06129916Not Yet Recruiting760Est. Jun 2027
+2 more trials

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
2028
Alliance PharmaceuticalsCT
Alliance PharmaceuticalsCT
Alliance PharmaceuticalsCT
Alliance PharmaceuticalsCT
Alliance PharmaceuticalsCT
Alliance PharmaceuticalsCT
Alliance PharmaceuticalsCT
Alliance PharmaceuticalsCT
Alliance PharmaceuticalsCT
Alliance PharmaceuticalsCT
Alliance PharmaceuticalsCT
Alliance PharmaceuticalsCT
Alliance PharmaceuticalsCT
Alliance PharmaceuticalsCT
Alliance PharmaceuticalsCT

Showing 15 of 50 trials with date data

Clinical Trials (50)

Total enrollment: 14,587 patients across 50 trials

NCT07004049Alliance PharmaceuticalsCT

Optimising TREATment for Severe Gram-Negative Bacterial Infections

Start: Apr 2025Est. completion: Dec 2028600 patients
Phase 4Recruiting
NCT01133600Alliance PharmaceuticalsCT

Outpatient Treatment of Gram Positive Wound Infections in the Diabetic Foot: A Pharmaco-economic Comparison of Daptomycin vs. Vancomycin Based Regimens

Start: Aug 2010Est. completion: Aug 20126 patients
Phase 4Terminated
NCT00824044Alliance PharmaceuticalsCT

Quantitative Electroencephalogram (QEEG) Predictors of Response to Psychotherapy Versus Antidepressant Treatment in Depression

Start: Jul 2008Est. completion: Mar 201139 patients
Phase 4Completed
NCT00707863Alliance PharmaceuticalsCT

Study of Brain Response to Emotional Pictures Using a Magnetic Resonance Imaging (fMRI) While on Escitalopram

Start: May 2008Est. completion: Dec 201217 patients
Phase 4Completed
NCT00589628Alliance PharmaceuticalsCT

Multi Center Prospective Registry of Infliximab Use for Childhood Uveitis

Start: Sep 2007Est. completion: Dec 201013 patients
Phase 4Completed
NCT01088958Alliance PharmaceuticalsCT

Effectiveness of Selling Micronutrient Sprinkles in Rural Kenya

Start: Jan 2007Est. completion: Sep 20147,200 patients
Phase 4Completed
NCT05657444Alliance PharmaceuticalsCT

Intra-arterial Tenecteplase During First Thrombectomy Attempt for Acute Stroke (BRETIS-TNK II)

Start: Mar 2023Est. completion: Mar 2025380 patients
Phase 3Completed
NCT05657457Alliance PharmaceuticalsCT

Improving Neurological Outcome for Acute Basilar Artery Occlusion With Sufficient Recanalization After Thrombectomy by Intraarterial Tenecteplase (INSIST-IT)

Start: Mar 2023Est. completion: May 2025145 patients
Phase 3Terminated
NCT04720157Alliance PharmaceuticalsCT

An International Prospective Open-label, Randomized, Phase III Study Comparing 177Lu-PSMA-617 in Combination With Standard of Care (SoC), Versus SoC Alone, in Adult Male Patients With Metastatic Hormone Sensitive Prostate Cancer (mHSPC)

Start: Jun 2021Est. completion: Feb 20271,145 patients
Phase 3Active Not Recruiting
NCT02349412Alliance PharmaceuticalsCT

Early Palliative Care With Standard Care or Standard Care Alone in Improving Quality of Life of Patients With Incurable Lung or Non-colorectal Gastrointestinal Cancer and Their Family Caregivers

Start: Jun 2015Est. completion: Jul 2019405 patients
Phase 3Completed
NCT01440088Alliance PharmaceuticalsCT

A Trial of TH-302 in Combination With Doxorubicin Versus Doxorubicin Alone to Treat Patients With Locally Advanced Unresectable or Metastatic Soft Tissue Sarcoma

Start: Sep 2011Est. completion: May 2016640 patients
Phase 3Completed
NCT00726622Alliance PharmaceuticalsCT

Laparoscopic-Assisted Resection or Open Resection in Treating Patients With Rectal Cancer

Start: Aug 2008Est. completion: Aug 2019486 patients
Phase 3Completed
NCT00288353Alliance PharmaceuticalsCT

Estimating and Reducing the Cardiovascular Risk of Patients With Schizophrenia Drugs From Lipid Measures and Ischemic Electrocardiographic Changes

Start: Jan 2006Est. completion: Dec 200848 patients
Phase 3Terminated
NCT05657470Alliance PharmaceuticalsCT

Rescue Thrombolysis for Medium Vessel Occlusion (RESCUE-TNK)

Start: Mar 2023Est. completion: Jun 202580 patients
Phase 2/3Completed
NCT04920838Alliance PharmaceuticalsCT

Early Treatment of Vulnerable Individuals With Non-Severe SARS-CoV-2 Infection

Start: Apr 2021Est. completion: Aug 2023600 patients
Phase 2/3Unknown
NCT01659437Alliance PharmaceuticalsCT

WHO Drug Study for Buruli Ulcer - Comparison of SR8 and CR8

Start: Dec 2012Est. completion: Jan 2018310 patients
Phase 2/3Completed
NCT07212595Alliance PharmaceuticalsCT

Biomarker and Renal Angina Validation to Assess Heart-Kidney Outcomes After Amino Acid Therapy

Start: Nov 2025Est. completion: Dec 202630 patients
Phase 2Not Yet Recruiting
NCT06987565Alliance PharmaceuticalsCT

Transcutaneous Vagus Nerve Stimulation in SLE

Start: May 2025Est. completion: May 202718 patients
Phase 2Not Yet Recruiting
NCT04486118Alliance PharmaceuticalsCT

Centrally Acting ACE Inhibition in SLE

Start: Oct 2021Est. completion: Mar 202636 patients
Phase 2Active Not Recruiting
NCT04335682Alliance PharmaceuticalsCT

Androgen Receptor Directed Therapy on Cognitive Function in Patients Treated With Darolutamide or Enzalutamide

Start: Aug 2021Est. completion: Aug 2026111 patients
Phase 2Active Not Recruiting
NCT03994796Alliance PharmaceuticalsCT

Genetic Testing in Guiding Treatment for Patients With Brain Metastases

Start: Oct 2019Est. completion: Jun 2028186 patients
Phase 2Suspended
NCT02334735Alliance PharmaceuticalsCT

A Comparison of Matured Dendritic Cells and Montanide® in Study Subjects With High Risk of Melanoma Recurrence

Start: Jul 2015Est. completion: Jul 202036 patients
Phase 2Completed
NCT01813214Alliance PharmaceuticalsCT

The Effects of Vemurafenib + Cobimetinib on Immunity in Patients With Melanoma

Start: Mar 2013Est. completion: Dec 20165 patients
Phase 2Terminated
NCT01100242Alliance PharmaceuticalsCT

Velcade and Sorafenib in Unresected or Metastatic Renal Cell Carcinoma

Start: Apr 2010Est. completion: Feb 201517 patients
Phase 2Terminated
NCT00516217Alliance PharmaceuticalsCT

Galiximab in Treating Patients With Relapsed or Refractory Hodgkin's Lymphoma

Start: Jun 2008Est. completion: Feb 201530 patients
Phase 2Completed
NCT00642941Alliance PharmaceuticalsCT

A Study of R1507 in Participants With Recurrent or Refractory Sarcoma

Start: Dec 2007Est. completion: Feb 2014317 patients
Phase 2Terminated
NCT00350883Alliance PharmaceuticalsCT

Cognitive Therapy for Negative Symptoms and Functioning

Start: Jul 2006Est. completion: Nov 201161 patients
Phase 2Completed
NCT00308074Alliance PharmaceuticalsCT

An Open-Label Trial of Aripiprazole in Autism Spectrum Disorders

Start: Feb 2006Est. completion: Feb 200914 patients
Phase 2Completed
NCT00074035Alliance PharmaceuticalsCT

Pentostatin in Treating Patients With Refractory Chronic Graft-Versus-Host Disease

Start: Dec 2003Est. completion: Nov 201439 patients
Phase 2Completed
NCT00053885Alliance PharmaceuticalsCT

PTK787/ZK 222584 in Treating Patients With Unresectable Malignant Mesothelioma

Start: Jul 2003Est. completion: Jun 200647 patients
Phase 2Completed
NCT00033748Alliance PharmaceuticalsCT

Vaccine Therapy in Treating Patients With Colorectal Cancer Metastatic to the Liver

Start: Dec 2001Est. completion: Jun 201056 patients
Phase 2Completed
NCT00006265Alliance PharmaceuticalsCT

Gemtuzumab Ozogamicin and High-Dose Cytarabine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia

Start: Mar 2001Est. completion: May 200560 patients
Phase 2Completed
NCT00003666Alliance PharmaceuticalsCT

Irofulven in Treating Patients With Relapsed or Refractory Non-small Cell Lung Cancer

Start: Nov 1998Est. completion: Jan 200636 patients
Phase 2Completed
NCT07443826Alliance PharmaceuticalsCT

CALM-AF-AI: Counteracting Age-related Loss of Muscle With AAV-Follistatin Combined With Angiogenesis-Inducing VEGF Plasmid Gene Therapy

Start: Mar 2026Est. completion: Jun 202812 patients
Phase 1/2Recruiting
NCT02571725Alliance PharmaceuticalsCT

PARP-inhibition and CTLA-4 Blockade in BRCA-deficient Ovarian Cancer

Start: Feb 2016Est. completion: Jul 202750 patients
Phase 1/2Active Not Recruiting
NCT00481988Alliance PharmaceuticalsCT

Treating Depression With Transcranial Direct Current Stimulation (tDCS)

Start: Mar 2007Est. completion: Jan 201120 patients
Phase 1/2Completed
NCT04390009Alliance PharmaceuticalsCT

Entire-body PET Scans for Multiple Sclerosis

Start: Sep 2024Est. completion: Dec 202520 patients
Phase 1Recruiting
NCT05526911Alliance PharmaceuticalsCT

A Phase 1, Drug-Drug Interaction Study of TBAJ-876 in Healthy Adults

Start: Jun 2022Est. completion: Sep 202228 patients
Phase 1Completed
NCT03582514Alliance PharmaceuticalsCT

PreOperative Brain Irradiation in Glioblastoma

Start: Apr 2022Est. completion: Jun 202518 patients
Phase 1Unknown
NCT04331288Alliance PharmaceuticalsCT

Effects of Ethanol on the Pharmacokinetics of PT-150 (Formerly ORG34517) (PT150 PK Study)

Start: Nov 2021Est. completion: Oct 202310 patients
Phase 1Completed
NCT02929407Ferring PharmaceuticalsFE 204205

A Study to Investigate the Safety and Effect of the Study Drug (FE 204205) in Patients With Cirrhotic Portal Hypertension

Start: Nov 2016Est. completion: Sep 20174 patients
Phase 1Terminated
NCT02614469Alliance PharmaceuticalsCT

A Food-Drug Interaction Study of Serum Urate After Oral Inosine

Start: Mar 2015Est. completion: May 201618 patients
Phase 1Completed
NCT01746810Alliance PharmaceuticalsCT

IR-guided Ablation (IRGA) Combined With Stereotactic Ablative Radiation (SABR) for Large Lung Tumors

Start: Jul 2012Est. completion: Oct 20151 patients
Phase 1Terminated
NCT01666353Alliance PharmaceuticalsCT

PET Quantitative Assessments of Solid Tumor Response to Immune Checkpoint Blockade Therapy

Start: Apr 2012Est. completion: Dec 201820 patients
Phase 1Completed
NCT01378156Alliance PharmaceuticalsCT

A Safety and Immunogenicity Study of a Plasmid DNA Prime and MVA Boost Vaccine in HIV-1 Infected Adults on ART

Start: Jun 2010Est. completion: May 20149 patients
Phase 1Completed
NCT01175642Alliance PharmaceuticalsCT

Cognitive Remediation and Functional Skills Training in Schizophrenia

Start: Jul 2007Est. completion: Sep 201075 patients
Phase 1Completed
NCT00197522Alliance PharmaceuticalsCT

Administration of Autologous Dendritic Cells (DCs) Infected With an Adenovirus Expressing Her-2

Start: Oct 2004Est. completion: May 20125 patients
Phase 1Completed
NCT06160947Alliance PharmaceuticalsCT

The Effect of Chiropractic Care on Opioid Use for Chronic Spinal Pain: A Feasibility Study

Start: Apr 2026Est. completion: Mar 202824 patients
N/ANot Yet Recruiting
NCT06129916Alliance PharmaceuticalsCT

Assessing the Acceptability, Feasibility, Effectiveness and Cost-effectiveness of LADB

Start: Nov 2025Est. completion: Jun 2027760 patients
N/ANot Yet Recruiting
NCT06662357Alliance PharmaceuticalsCT

Family Connections

Start: Jan 2025Est. completion: Sep 2028300 patients
N/ARecruiting

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Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

4 actively recruiting trials targeting 14,587 patients
3 companies competing in this space

Related Indications

Heart Failure(334)Hypertension(333)Coronary Artery Disease(295)Atrial Fibrillation(288)Pulmonary Arterial Hypertension(103)Acute Coronary Syndrome(62)Pulmonary Hypertension(55)Essential Hypertension(32)Coronary Heart Disease(28)Aortic Valve Stenosis(27)