Peripheral Artery Disease
Pipeline by Development Stage
Drug Modality Breakdown
Peripheral Artery Disease is a cardiovascular market with limited current commercial activity but growing pipeline momentum.
Key Trends
- Early-stage pipeline development with 98 total trials across all phases
- Heavy concentration of hiring at Big Pharma (J&J, AstraZeneca, Novartis) suggesting major investment
- Clinical Operations roles commanding premium salaries ($356K avg), indicating complex trial infrastructure
Career Verdict
PAD is a niche but strategically important area with strong pharma backing; suitable for specialists seeking deep cardiovascular expertise and emerging market entry.
AI-generated market analysis based on FDA, CMS, ClinicalTrials.gov, and hiring data
Market Leaders
| # | Product | Company | Revenue | Share | Stage | Trend | LOE |
|---|---|---|---|---|---|---|---|
| 1 | Data unavailable | Data unavailable | — | — | Unknown |
Drug Class Breakdown
Unable to assess
Career Outlook
GrowingPAD is a strategically prioritized cardiovascular area with over 3,400 active positions concentrated at top-tier companies. The disease area is transitioning from research to development phase, with growing investment in clinical operations and medical affairs suggesting anticipated near-term commercialization efforts. Entry now positions professionals to own key roles as candidates advance toward regulatory approval and launch.
Breaking In
Target clinical operations and medical affairs roles at J&J or AstraZeneca to build cardiovascular expertise while participating in PAD pipeline development.
For Experienced Professionals
Leverage PAD's early commercialization phase to move into leadership roles in clinical development, market access, or field-based medical affairs before competitive markets mature.
In-Demand Skills
Best For
Hiring Landscape
PAD is actively staffed by three major pharmaceutical companies with Johnson & Johnson leading at 1,691 positions (49% of total hiring). Clinical Operations commands the highest salaries ($356K average), reflecting the complexity of PAD trials, while Commercial roles represent the largest volume (661 positions). This distribution suggests investment in both pipeline development and eventual market launch infrastructure.
By Department
Significant hiring volume at premium salaries indicates aggressive pharma investment; Clinical Operations roles offer the highest compensation and career advancement potential.
On Market (1)
Approved therapies currently available
Competitive Landscape
30 companies ranked by most advanced pipeline stage
Trial Timeline
Clinical trial activity over time
Showing 15 of 50 trials with date data
Clinical Trials (50)
Total enrollment: 262,764 patients across 50 trials
Vorapaxar and Lower Extremity Bypass Grafts
Adenosine-induced Myocardial Blood Flow in Peripheral Artery Disease Patients
Temsirolimus Adventitial Delivery to Improve ANGioplasty and/or Atherectomy Revascularization Outcomes Below the Knee
RANGER™ Paclitaxel Coated Balloon vs Standard Balloon Angioplasty
Efficacy and Safety of Rivaroxaban in Reducing the Risk of Major Thrombotic Vascular Events in Subjects With Symptomatic Peripheral Artery Disease Undergoing Peripheral Revascularization Procedures of the Lower Extremities
A Study Comparing Cardiovascular Effects of Ticagrelor and Clopidogrel in Patients With Peripheral Artery Disease
Study of AMG0001 to Improve Ulcer Healing and Perfusion in Subjects With Peripheral Ischemic Ulcers
Hepatocyte Growth Factor to Improve Functioning in PAD
Safety, Tolerability and Efficacy of ACZ885 on Leg Artery Structure in Patients With Peripheral Artery Disease
Investigational Device Exemption Study to Determine the Safety and Efficacy of the Astron and Pulsar Stents
Evaluation of Concomitant Administration of Cilostazol and Probucol on Biomarkers, Endothelial Function and Safety
AMS INSIGHT 1 Study - Bioabsorbable Metal Stent Investigation in Chronic Limb Ischemia Treatment
A Study of the SMART Stent in the Treatment SFA Disease.
Study of PVS-10200 for the Treatment of Restenosis in Patients With Peripheral Artery Disease (TRIUMPH)
Injection of Autologous CD34-Positive Cells for Critical Limb Ischemia
A Study to Investigate the Effect of Oral Ticagrelor on the Pharmacokinetics of Oral Rosuvastatin When Given in Healthy Participants
Use of Autologous Concentrated Bone Marrow Aspirate in Preventing Wound Complications in Below Knee Amputation (BKA)
The THOR IDE Study
BRight Pharmacokinetic Study
Safety and Effectiveness Evaluation of Peripheral Orbital Atherectomy
Leg Heat Therapy in Peripheral Artery Disease
PMCF Study for Peripheral Arteries Below the Knee (BTK)
Trial to Assess the Safety and Efficacy of Sirolimus-Coated Balloon vs. Uncoated Standard Angioplasty for the Treatment of Below-the-knee Peripheral Arterial Disease
ACOART BTK RENEW：A Post Market Clinical Study
Acoart SCB SFA: Sirolimus Coated Balloon Catheter in the Treatment of Femoropopliteal Artery Stenosis
Disrupt PAD BTK II Study With the Shockwave Peripheral IVL System
Imaging-Guided Vessel Sizing in the Tibial Arteries
BIOTRONIK Dynetic-35 Stent for the Treatment of Peripheral Iliac Lesions
Sirolimus- vs. Paclitaxel-Drug Coated Ballons in Patients With Peripheral Artery Disease
A Study Related to the VOYAGER PAD Trial to Learn More About the Target Population for Xarelto in French Patients
SUCCESS (SelUtion, Safety, effiCaCy, hEalth economicS and promS) PTA Study
BRight DCB First-in-Human Study
Sirolimus Coated Balloon Versus Standard Balloon for SFA and Popliteal Artery Disease
ABLUMINUS DES BTK Registry - FIM
SirolimUs CoaTed Balloon for The TrEatment of Below The Knee Arterial Disease
Implementation of Vascular Care Team to Improve Medical Management of PAD Patients
Acotec DCB Post Market Clinical Follow-up
FlowMet-R Blood Flow Measurement for the Diagnosis of Peripheral Artery Disease and Critical Limb Ischemia
Peripheral Artery Disease in Patients With Stable Coronary Artery Disease in General Practice: Prevalence, Management and Clinical Outcomes.
Radial accEss for nAvigation to Your CHosen Lesion for Peripheral Vascular Intervention: REACH PVI
Clinical Use and Safety of the Xtreme Touch (Magic Touch PTA)- Neo Sirolimus Coated PTA Balloon Catheter in the Treatment of Infrainguinal Peripheral Arterial Disease
Telephone Health Coaching and Remote Exercise Monitoring for Peripheral Artery Disease
AcoArt IV / SFA in China:Drug-eluting Balloon for SFA Angioplasty Evaluation in China
Percutaneous Intervention Versus Surgery in the Treatment of Common Femoral Artery Lesions
SHOWME-PAD (Peripheral Artery Disease)
BIOTRONIK 4French for AMBulatory Peripheral Intervention
VascTrac Peripheral Arterial Disease (PAD) Study
Tack Optimized Balloon Angioplasty Study of the Tack Endovascular System™ in Femoropoliteal Arteries
AcoArt Ⅱ/ BTK China: Drug-eluting Balloon for Below-The-Knee Angioplasty Evaluation in China
Complete Lesion Assessment With ffR and IVUS TechnologY
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Key Insights
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.