Obstructive Hypertrophic Cardiomyopathy

Cardiovascular
2
Pipeline Programs
3
Companies
3
Clinical Trials
1 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
1
0
0
0
1
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

3 companies ranked by most advanced pipeline stage

Bayer
BayerLEVERKUSEN, Germany
1 program
1
BAY3723113Phase 31 trial
Active Trials
NCT07023341Active Not Recruiting36Est. May 2028
Cytokinetics
CytokineticsSOUTH SAN FRANCISCO, CA
1 program
1
CK-3773274Phase 11 trial
Active Trials
NCT04783766CompletedEst. Aug 2021
Bristol Myers Squibb
1 program
mavacamtenN/A1 trial
Active Trials
NCT06023186Recruiting20Est. Sep 2026

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
2028
BayerBAY3723113
CytokineticsCK-3773274
Bristol Myers Squibbmavacamten

Clinical Trials (3)

Total enrollment: 56 patients across 3 trials

NCT07023341BayerBAY3723113

A Study to Learn More About How Well Aficamten Works in Japanese Participants With Symptomatic Obstructive Hypertrophic Cardiomyopathy

Start: Jun 2025Est. completion: May 202836 patients
Phase 3Active Not Recruiting
NCT04783766CytokineticsCK-3773274

Safety, Tolerability and Pharmacokinetics Study of CK-3773274

Start: Apr 2021Est. completion: Aug 2021
Phase 1Completed
NCT06023186Bristol Myers Squibbmavacamten

Effect of Mavacamten Treatment on Coronary Flow Reserve in oHCM

Start: Nov 2023Est. completion: Sep 202620 patients
N/ARecruiting

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Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

1 late-stage (Phase 3) programs — potential near-term approvals
1 actively recruiting trials targeting 56 patients
3 companies competing in this space

Related Indications

Heart Failure(334)Hypertension(333)Coronary Artery Disease(295)Atrial Fibrillation(288)Pulmonary Arterial Hypertension(103)Acute Coronary Syndrome(62)Pulmonary Hypertension(55)Essential Hypertension(32)Coronary Heart Disease(28)Aortic Valve Stenosis(27)