Metastatic Solid Tumors

Oncology
9
Pipeline Programs
7
Companies
9
Clinical Trials
3 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
8
1
0
0
0
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

7 companies ranked by most advanced pipeline stage

Qilu Pharmaceutical
Qilu PharmaceuticalChina - Jinan
1 program
1
QLC5513 IV infusionPhase 1/21 trial
Active Trials
NCT07272590Not Yet RecruitingEst. Aug 2031
Erasca
ErascaSAN DIEGO, CA
2 programs
2
ERAS-0015Phase 11 trial
ERAS-4001Phase 11 trial
Active Trials
NCT06983743RecruitingEst. Dec 2028
NCT07021898RecruitingEst. Dec 2028
M&
Merck & Co.RAHWAY, NJ
2 programs
2
M1231Phase 11 trial
M6223Phase 11 trial
Active Trials
NCT04695847CompletedEst. Jun 2023
NCT04457778CompletedEst. Jun 2023
Astex Pharmaceuticals
Astex PharmaceuticalsUK - Cambridge
1 program
1
AT13387Phase 11 trial
Active Trials
NCT00878423CompletedEst. Mar 2014
BeOne Medicines
BeOne MedicinesCA - San Carlos
1 program
1
BGB-53038Phase 11 trial
Active Trials
NCT06585488RecruitingEst. Dec 2026
Takeda
TakedaTOKYO, Japan
1 program
1
TAK-117Phase 11 trial
Active Trials
NCT01449370Completed125Est. Jan 2016
ImmunityBio
ImmunityBioSAN DIEGO, CA
1 program
1
aldoxorubicinPhase 11 trial
Active Trials
NCT02235688Completed30Est. Jan 2017

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
2028
2029
2030
2031
Qilu PharmaceuticalQLC5513 IV infusion
ErascaERAS-4001
ErascaERAS-0015
BeOne MedicinesBGB-53038
Merck & Co.M1231
Merck & Co.M6223
ImmunityBioaldoxorubicin
TakedaTAK-117
Astex PharmaceuticalsAT13387

Clinical Trials (9)

Total enrollment: 155 patients across 9 trials

NCT07272590Qilu PharmaceuticalQLC5513 IV infusion

Study of QLC5513 in Combination With Epalolimab Tovolimab (QL1706) ± Platinum in Patients With Advanced or Metastatic Malignant Solid Tumors

Start: Dec 2025Est. completion: Aug 2031
Phase 1/2Not Yet Recruiting
NCT07021898ErascaERAS-4001

A Study of ERAS-4001 in Patients With Advanced or Metastatic Solid Tumors.

Start: Aug 2025Est. completion: Dec 2028
Phase 1Recruiting
NCT06983743ErascaERAS-0015

A Study of ERAS-0015 in Patients With Advanced or Metastatic Solid Tumors

Start: Jun 2025Est. completion: Dec 2028
Phase 1Recruiting
NCT06585488BeOne MedicinesBGB-53038

A First-in-human Study of BGB-53038, a Pan-KRAS Inhibitor, Alone or in Combinations in Participants With Advanced or Metastatic Solid Tumors With KRAS Mutations or Amplification

Start: Nov 2024Est. completion: Dec 2026
Phase 1Recruiting
NCT04695847Merck & Co.M1231

M1231 in Participants With Solid Tumors

Start: Jan 2021Est. completion: Jun 2023
Phase 1Completed
NCT04457778Merck & Co.M6223

First in Human Study of M6223

Start: Jul 2020Est. completion: Jun 2023
Phase 1Completed
NCT02235688ImmunityBioaldoxorubicin

Study to Investigate the Safety and Activity of Aldoxorubicin Plus Gemcitabine in Subjects With Metastatic Solid Tumors

Start: Aug 2014Est. completion: Jan 201730 patients
Phase 1Completed
NCT01449370TakedaTAK-117

Dose Escalation Study of TAK-117 (MLN1117) in Subjects With Advanced Cancer

Start: Oct 2011Est. completion: Jan 2016125 patients
Phase 1Completed
NCT00878423Astex PharmaceuticalsAT13387

Study to Assess the Safety of Escalating Doses of AT13387 in Patients With Metastatic Solid Tumors

Start: May 2008Est. completion: Mar 2014
Phase 1Completed

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Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

3 actively recruiting trials targeting 155 patients
7 companies competing in this space

Related Indications

Breast Cancer(530)Non-small Cell Lung Cancer(373)Prostate Cancer(371)Multiple Myeloma(244)Advanced Solid Tumors(221)Acute Myeloid Leukemia(204)Cancer(187)Neoplasms(173)Colorectal Cancer(166)Advanced Solid Tumor(165)