Carcinoma, Small Cell Lung

Oncology
4
Pipeline Programs
3
Companies
3
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
0
0
4
0
Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

Vaccine
2100%
+ 2 programs with unclassified modality

Competitive Landscape

3 companies ranked by most advanced pipeline stage

EpicentRx
EpicentRxCA - La Jolla
2 programs
2
RRx-001 + eLOOP DevicePhase 31 trial
RRx-001 + eLOOP DevicePhase 31 trial
Active Trials
NCT03699956TerminatedEst. Mar 2024
NCT05566041Active Not RecruitingEst. Dec 2025
Eli Lilly and Company
Eli Lilly and CompanyINDIANAPOLIS, IN
1 program
1
BEC2 VaccinePhase 3Vaccine
M&
Merck & Co.RAHWAY, NJ
1 program
1
BEC2 VaccinePhase 3Vaccine1 trial
Active Trials
NCT00037713Completed515Est. Oct 2002

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
EpicentRxRRx-001 + eLOOP Device
EpicentRxRRx-001 + eLOOP Device
Merck & Co.BEC2 Vaccine

Clinical Trials (3)

Total enrollment: 515 patients across 3 trials

NCT05566041EpicentRxRRx-001 + eLOOP Device

A Phase 3, Controlled, Open-label, Global Randomized Study of RRx-001 With a Platinum Doublet or a Platinum Doublet in Small Cell Lung Cancer

Start: Aug 2022Est. completion: Dec 2025
Phase 3Active Not Recruiting
NCT03699956EpicentRxRRx-001 + eLOOP Device

RRx-001 Sequentially With a Platinum Doublet or a Platinum Doublet in Third-Line or Beyond in Patients With Small Cell Lung Cancer

Start: Dec 2018Est. completion: Mar 2024
Phase 3Terminated
NCT00037713Merck & Co.BEC2 Vaccine

Survival in a Randomized Phase III Trial in Patients With Limited Disease (LD) Small Cell Lung Cancer Vaccinated With Adjuvant BEC2 and BCG

Start: Sep 1998Est. completion: Oct 2002515 patients
Phase 3Completed

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Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

4 late-stage (Phase 3) programs — potential near-term approvals
Vaccine is the dominant modality (100% of programs)
3 companies competing in this space

Related Indications

Breast Cancer(530)Non-small Cell Lung Cancer(373)Prostate Cancer(371)Multiple Myeloma(244)Advanced Solid Tumors(221)Acute Myeloid Leukemia(204)Cancer(187)Neoplasms(173)Colorectal Cancer(166)Advanced Solid Tumor(165)