Advanced Heart Failure

Cardiovascular
2
Pipeline Programs
3
Companies
13
Clinical Trials
2 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
0
0
0
2
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

3 companies ranked by most advanced pipeline stage

Abbott
AbbottABBOTT PARK, IL
4 programs
1
CardioMEMS HF SystemPhase 45 trials
HeartMate 3™ left ventricular assist systemN/A1 trial
HeartMate 3™ left ventricular assist systemN/A1 trial
Screening for Advanced Heart Failure Treatment (SEE-HF)N/A1 trial
Active Trials
NCT04915924Completed358Est. Jun 2024
NCT04703855Terminated3Est. Jun 2022
NCT01626404Completed99Est. Feb 2016
+5 more trials
Novo Nordisk
Novo NordiskBAGSVAERD DENMARK, Denmark
1 program
1
CardioMEMS HF SystemPhase 4
CorWave
CorWaveFrance - Clichy
1 program
LVASN/A1 trial
Active Trials
NCT06907017Recruiting20Est. May 2028

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
2028
2029
2030
2031
AbbottCardioMEMS HF System
CorWaveLVAS
AbbottCardioMEMS HF System
AbbottCardioMEMS HF System
AbbottCardioMEMS HF System
AbbottCardioMEMS HF System
AbbottHeartMate 3™ left ventricular assist system
AbbottHeartMate 3™ left ventricular assist system
AbbottCardioMEMS HF System
AbbottCardioMEMS HF System
AbbottCardioMEMS HF System
AbbottCardioMEMS HF System
AbbottScreening for Advanced Heart Failure Treatment (SEE-HF)

Clinical Trials (13)

Total enrollment: 6,034 patients across 13 trials

NCT05284955AbbottCardioMEMS HF System

Screening for Advanced Heart Failure IN Stable outPatientS - The SAINTS Study (SAINTS B)

Start: Mar 2023Est. completion: Dec 202560 patients
Phase 4Unknown
NCT06907017CorWaveLVAS

CorWave LVAS FIH Study

Start: May 2025Est. completion: May 202820 patients
N/ARecruiting
NCT06779552AbbottCardioMEMS HF System

CardioMEMS HF System Coverage with Evidence Development Study

Start: Feb 2025Est. completion: Mar 20321,000 patients
N/ARecruiting
NCT06306573AbbottCardioMEMS HF System

CardioMEMS HF System Real-World Evidence Post-Approval Study

Start: Dec 2022Est. completion: Dec 20282,500 patients
N/AEnrolling By Invitation
NCT05428384AbbottCardioMEMS HF System

Validation of CardioMEMS HF System Cardiac Output Algorithm IDE

Start: Aug 2022Est. completion: Jan 202489 patients
N/ACompleted
NCT05731466AbbottCardioMEMS HF System

Exercise Right Ventricular Coupling in HFpEF

Start: Oct 2021Est. completion: Dec 202530 patients
N/AUnknown
NCT04703855AbbottHeartMate 3™ left ventricular assist system

Hong Kong and Taiwan HM3 PMS

Start: Jul 2021Est. completion: Jun 20223 patients
N/ATerminated
NCT04915924AbbottHeartMate 3™ left ventricular assist system

Post Market Surveillance of the HeartMate 3 Left Ventricular Assist System in Korea

Start: Oct 2020Est. completion: Jun 2024358 patients
N/ACompleted
NCT03247829AbbottCardioMEMS HF System

Investigation to Optimize Hemodynamic Management of Left Ventricular Assist Devices Using the CardioMEMS™

Start: Aug 2017Est. completion: Jun 2020101 patients
N/ACompleted
NCT02954341AbbottCardioMEMS HF System

CardioMEMS HF System OUS Post Market Study

Start: Jul 2016Est. completion: Dec 2023321 patients
N/ACompleted
NCT02693691AbbottCardioMEMS HF System

CardioMEMS European Monitoring Study for Heart Failure

Start: May 2016Est. completion: Mar 2020239 patients
N/ACompleted
NCT02279888AbbottCardioMEMS HF System

CardioMEMS HF System Post Approval Study

Start: Jan 2015Est. completion: Oct 20191,214 patients
N/ACompleted
NCT01626404AbbottScreening for Advanced Heart Failure Treatment (SEE-HF)

Screening for Advanced Heart Failure Treatment (SEE-HF)

Start: Oct 2012Est. completion: Feb 201699 patients
N/ACompleted

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Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

2 actively recruiting trials targeting 6,034 patients
3 companies competing in this space

Related Indications

Heart Failure(334)Hypertension(333)Coronary Artery Disease(295)Atrial Fibrillation(288)Pulmonary Arterial Hypertension(103)Acute Coronary Syndrome(62)Pulmonary Hypertension(55)Essential Hypertension(32)Coronary Heart Disease(28)Aortic Valve Stenosis(27)