Acute-On-Chronic Liver Failure
Gastroenterology
1
Pipeline Programs
2
Companies
2
Clinical Trials
1 recruiting
0
Approved Products
Pipeline by Development Stage
Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
0
0
1
0
Early DiscoveryClinical DevelopmentMarket
Competitive Landscape
2 companies ranked by most advanced pipeline stage
Trial Timeline
Clinical trial activity over time
2021
2022
2023
2024
2025
2026
2027
GrifolsSMT + PE-A 5%
CytoSorbentsCytoSorb
Clinical Trials (2)
Total enrollment: 20 patients across 2 trials
Short-term Survival of Subjects With Acute-on-chronic Liver Failure After Plasma Exchange With Human Serum Albumin 5%
Start: Feb 2019Est. completion: Apr 2025
Phase 3Terminated
COOLEY- Study: ACute on ChrOnic Liver FailurE Using the CYtosorb Device
Start: Jun 2024Est. completion: Sep 202720 patients
N/ARecruiting
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Phase Legend
Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available
Key Insights
1 late-stage (Phase 3) programs — potential near-term approvals
1 actively recruiting trials targeting 20 patients
2 companies competing in this space