Sangamo Therapeutics

CA - RichmondBiotechnology1 H-1B visas (FY2023)

Focus: Sangamo Therapeutics is a mid-cap biotech focused on gene therapy and cell therapy using zinc finger nuclease (ZFN) technology and adeno-associated virus (AAV) delivery platforms. The company targets rare and severe diseases across neurology, infectious diseases, and metabolic indications.

Neurology Infectious Diseases Rare Diseases Metabolic Diseases

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About Sangamo Therapeutics

AI assessmentNot Hiring

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Why Work Here

Data completeness

1/9 — Limited

Company HealthSolid

Pipeline

Early-stage

30 total

LOE Risk

Protected

No near-term cliffs

Hiring

0 open

Automated analysis based on publicly available data (FDA, SEC, ClinicalTrials.gov). May be incomplete or delayed. This score does not reflect insider knowledge and should not be used as the sole basis for investment or employment decisions.

Pipeline & Clinical Trials

BIVV003

Blood and Lymphatic Diseases

N/A

Clinical Trials (1)

NCT05145062Long - Term Follow Up of Sickle Cell Disease and Beta-thalassemia Subjects Previously Exposed to BIVV003 or ST-400.

N/A

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Data Sources

Drug label: DailyMed / FDA
Clinical trials: ClinicalTrials.gov
Patent data: FDA Orange Book
Spending data: CMS Medicare

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.

Access to cutting-edge gene therapy platforms (AAV, ZFN) with potential to treat previously intractable diseases like Alzheimer's and Parkinson's
Diverse pipeline spanning 20+ programs across high-need therapeutic areas including neurology, rare metabolic diseases, and HIV
Opportunity to work on Phase 2 programs (CERE-110, CERE-120, SB-509) with clinical validation and upcoming catalysts

Watch Out For

No current commercial revenue generates financial runway risk; pre-commercial biotech operations require tolerance for capital dependency
No Phase 3 programs in pipeline signals extended timeline to first approval (likely 3-5+ years), with no near-term revenue inflection catalysts
Zero active job postings and limited recent H1B sponsorship (1 approval in 2023) suggest minimal active hiring and constrained growth plans

Generated by Claude from Sangamo Therapeutics's SEC filings, pipeline programs, hiring velocity, FDA actions, and WARN data. Inference, not editorial — verify before quoting.

There are no disallowed treatments

HIV-1-infection

N/A

Clinical Trials (1)

NCT04201782Long-term Follow-up of HIV Subjects Exposed to SB-728-T or SB-728mR-T

N/A

Blood sample

Kidney Transplant Rejection

N/A

Clinical Trials (1)

NCT05987527Long-Term Follow-Up of TX200-TR101 (STEADFAST Long Term)

N/A

SB-318

Hemophilia B

N/A

Clinical Trials (1)

NCT04628871Long Term Follow-up (LTFU) of Subjects Who Received SB-318, SB-913, or SB-FIX

N/A

ST-920

Fabry Disease

N/A

Clinical Trials (1)

NCT05039866Long-Term Follow-up of Subjects Who Were Treated With ST-920

N/A

ZFN modified T cells

HIV

Phase 1

Clinical Trials (1)

NCT00842634Autologous T-Cells Genetically Modified at the CCR5 Gene by Zinc Finger Nucleases SB-728 for HIV

Phase 1

hVEGF-A

Diabetic Neuropathy

Phase 1

Clinical Trials (1)

NCT00110500Clinical Trial of SB-509-0401 in Subjects With Diabetic Neuropathy

Phase 1

CERE-120: AAV2-NTN

Parkinson's Disease

Phase 1

Clinical Trials (1)

NCT00252850Safety of CERE-120 (AAV2-NTN) in Subjects With Idiopathic Parkinson's Disease

Phase 1

CERE-110: Adeno-Associated Virus Delivery of NGF

Alzheimer's Disease

Phase 1

Clinical Trials (1)

NCT00087789CERE-110 in Subjects With Mild to Moderate Alzheimer's Disease

Phase 1

SB-728mR-HSPC Infusion 3 days following busulfan conditioning

HIV

Phase 1

SB-728-T

HIV Infection

Phase 1

Clinical Trials (1)

NCT01044654Phase 1 Dose Escalation Study of Autologous T-cells Genetically Modified at the CCR5 Gene by Zinc Finger Nucleases in HIV-Infected Patients

Phase 1

SB-FIX

Hemophilia B

Phase 1

Clinical Trials (1)

NCT02695160Ascending Dose Study of Genome Editing by Zinc Finger Nuclease Therapeutic SB-FIX in Subjects With Severe Hemophilia B

Phase 1

SB-318

MPS I

Phase 1/2

Clinical Trials (1)

NCT02702115Ascending Dose Study of Genome Editing by the Zinc Finger Nuclease (ZFN) Therapeutic SB-318 in Subjects With MPS I

Phase 1/2

ST-503

Chronic Neuropathic Pain

Phase 1/2

Clinical Trials (1)

NCT06980948Safety and Tolerability Study of ST-503 for Refractory Pain Due to Peripheral Neuropathy (Small Fiber Predominant, SFN)

Phase 1/2

ST-920

Fabry Disease

Phase 1/2

Clinical Trials (1)

NCT04046224Dose-Ranging Study of ST-920, an AAV2/6 Human Alpha Galactosidase A Gene Therapy in Subjects With Fabry Disease (STAAR)

Phase 1/2

SB-728-T

HIV

Phase 1/2

Clinical Trials (1)

NCT01252641Study of Autologous T-cells Genetically Modified at the CCR5 Gene by Zinc Finger Nucleases in HIV-Infected Subjects

Phase 1/2

ST-400 Investigational product

Transfusion Dependent Beta-thalassemia

Phase 1/2

Clinical Trials (1)

NCT03432364A Study to Assess the Safety, Tolerability, and Efficacy of ST-400 for Treatment of Transfusion-Dependent Beta-thalassemia (TDT)

Phase 1/2

SB-728-T

HIV

Phase 1/2

Clinical Trials (1)

NCT01543152Dose Escalation Study of Cyclophosphamide in HIV-Infected Subjects on HAART Receiving SB-728-T

Phase 1/2

TX200-TR101

Kidney Transplant Rejection

Phase 1/2

Clinical Trials (1)

NCT04817774Safety & Tolerability Study of Chimeric Antigen Receptor T-Reg Cell Therapy in Living Donor Renal Transplant Recipients

Phase 1/2

Plerixafor

Sickle Cell Disease

Phase 1/2

Clinical Trials (1)

NCT03653247A Study to Assess the Safety, Tolerability, and Efficacy of BIVV003 for Autologous Hematopoietic Stem Cell Transplantation in Patients With Severe Sickle Cell Disease

Phase 1/2

SB-728mR-T

Human Immunodeficiency Virus (HIV)

Phase 1/2

Clinical Trials (1)

NCT02225665Repeat Doses of SB-728mR-T After Cyclophosphamide Conditioning in HIV-Infected Subjects on HAART

Phase 1/2

CERE-120: Adeno-Associated Virus Delivery of Neurturin

Idiopathic Parkinson's Disease

Phase 1/2

Clinical Trials (1)

NCT00985517Safety and Efficacy of CERE-120 in Subjects With Parkinson's Disease