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Diabetic Neuropathy

Neurology
8
Pipeline Programs
11
Companies
12
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
2
0
3
0
0
3
Early DiscoveryClinical DevelopmentMarket

Neurology is a $26.9B market dominated by a single blockbuster anticoagulant (ELIQUIS), representing a mature but consolidating therapeutic area.

$26.9B marketMature→ Stable30 products15 companies

Key Trends

  • Extreme market concentration: 68% of spending driven by one FXa inhibitor product
  • Psychiatric and migraine therapies emerging as secondary growth drivers
  • High clinical trial activity (8,279 trials) signals continued pipeline development

Career Verdict

Neurology offers solid career stability with good hiring demand, but limited upside growth—best suited for professionals seeking established market positions rather than emerging-area innovation.

AI-generated market analysis based on FDA, CMS, ClinicalTrials.gov, and hiring data

Market Leaders

#1ELIQUISStable
$18.3B
Bristol Myers Squibb·Launch15.0yr
$1.8B
#3BRILINTAStable
$692M
AstraZeneca·Peak10.2yr
#4NUPLAZIDStable
$596M
$530M
Johnson & Johnson·Peak15.6yr

Drug Class Breakdown

FXa Inhibitors (anticoagulant)
$18.3B(68%)

market-defining single product

Dopamine/Serotonin Antagonists (psychiatric)
$2.4B(9%)

stable mature class

P2Y12 Receptor Antagonists (antiplatelet)
$692M(3%)

niche but stable

5-HT2A Inverse Agonists (psychiatric)
$596M(2%)

specialty indication focus

CGRP Receptor Antagonists (migraine)
$931M(3%)

emerging growth segment

Immunomodulators (MS)
$747M(3%)

stable with LOE risk

Other mechanisms
$2.6B(10%)

diverse small products

Career Outlook

Stable

Neurology represents a mature, cash-generative market with limited growth tailwinds but strong hiring stability. The dominance of ELIQUIS creates a bifurcated career landscape: high-opportunity positions in emerging segments (CGRP antagonists, psychiatric therapeutics) and commoditized roles in anticoagulant franchises. Job availability is solid but growth expectations should be tempered relative to oncology or immunology.

Breaking In

Entry-level professionals should target clinical operations or commercial support roles at J&J, AstraZeneca, or Sanofi to build domain expertise in neurology disease states and competitive dynamics.

For Experienced Professionals

Experienced professionals should prioritize emerging mechanism roles (CGRP, tau-targeting programs) or pivot to medtech/neurotech (Stryker, Medtronic) to capture higher growth and salary potential than traditional pharma incumbents.

In-Demand Skills

Medical Science Liaisons (MSL) for specialist engagementClinical trial operations expertisePsychiatric/neurodegenerative disease educationRegulatory affairs (given patent cliff activity)Commercial strategy around branded/generic transitions

Best For

Medical Science LiaisonCommercial Brand Manager (anticoagulant/psychiatric franchises)Clinical Operations ManagerRegulatory Affairs SpecialistClinical Development Manager (CGRP/immunomodulator pipelines)

Hiring Landscape

$100K-$199K

Neurology shows moderate but distributed hiring across pharma and medtech employers, with 4,186 total jobs listed. Commercial functions lead (947 roles, $169K avg), followed by clinical operations (467 roles, $132K avg), indicating bias toward commercialization over R&D. Takeda leads external hiring (762 jobs) with strong representation in contract research and CRO spaces.

4,186
Open Roles
5
Companies Hiring
5
Departments

Top Hiring Companies

762Growing
434Stable
302Stable

By Department

Commercial(23%)
$169K
Clinical Operations(11%)
$132K
Engineering(8%)
$199K
IT(4%)
$100K
Manufacturing(3%)
$170K

Commercial and clinical operations roles dominate, offering stable mid-career positions; engineering roles command premium salaries ($199K), suggesting strong device/neurotech hiring pockets.

Competitive Landscape

9 companies ranked by most advanced pipeline stage

Pfizer
PfizerNEW YORK, NY
2 programs
2
PregabalinPhase 41 trial
sildenafilPhase 41 trial
Active Trials
NCT00573261Completed40Est. May 2008
NCT00194909Completed8Est. Jul 2006
Boston Scientific
Boston ScientificCA - Valencia
1 program
1
Precision Spinal Cord StimulationPhase 41 trial
Active Trials
NCT00487981Terminated1Est. Sep 2008
Dong-A ST
Dong-A STKorea - Seoul
2 programs
1
1
DA-9801 300mgPhase 21 trial
600㎍ of DA-3030 InjectionPhase 11 trial
Active Trials
NCT01820715Completed31
NCT01822925Completed128Est. Jan 2015
Oregon Therapeutics
Oregon TherapeuticsFrance - Paris
1 program
1
Centella asiatica selected triterpenesPhase 21 trial
Active Trials
NCT00608439Completed43Est. Aug 2011
Ergomed
ErgomedUK - Guildford
1 program
1
ExperimentalPhase 2
Sangamo Therapeutics
1 program
1
hVEGF-APhase 11 trial
Active Trials
NCT00110500Completed12Est. Jan 2008
UCB Pharma
UCB PharmaBelgium - Brussels
3 programs
SPM 927PHASE_2_31 trial
lacosamidePHASE_2_31 trial
SPM 927PHASE_31 trial
Active Trials
NCT00235469Completed496Est. Jun 2005
NCT00235443Completed451Est. Jul 2008
NCT00238524Completed357Est. Jan 2005
UNION therapeutics
UNION therapeuticsDenmark - Hellerup
1 program
Understanding Risk Factors and Determinants for Neuropathic PainN/A1 trial
Active Trials
NCT02402361Completed200Est. Mar 2021
Johnson & Johnson
Johnson & JohnsonNEW BRUNSWICK, NJ
1 program
JNJ-42160443PHASE_21 trial
Active Trials
NCT00993018Terminated77Est. Jun 2011

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
Boston ScientificPrecision Spinal Cord Stimulation
PfizerPregabalin
Pfizersildenafil
UCB PharmaSPM 927
UCB Pharmalacosamide
UCB PharmaSPM 927
Dong-A STDA-9801 300mg
Johnson & JohnsonJNJ-42160443
Oregon TherapeuticsCentella asiatica selected triterpenes
Dong-A ST600㎍ of DA-3030 Injection
Sangamo TherapeuticshVEGF-A
UNION therapeuticsUnderstanding Risk Factors and Determinants for Neuropathic Pain

Clinical Trials (12)

Total enrollment: 1,844 patients across 12 trials

NCT00487981Boston ScientificPrecision Spinal Cord Stimulation

Spinal Cord Stimulation for Painful Diabetic Neuropathy

Start: Feb 2007Est. completion: Sep 20081 patients
Phase 4Terminated

A Randomized Double-Blind Study Testing the Effects of Pregabalin on Diabetic Neuropathy

Start: Mar 2006Est. completion: May 200840 patients
Phase 4Completed

An Open Label, Dose Finding Trial of Viagra for the Treatment of Neuropathic Pain (in Diabetes Mellitus)

Start: Aug 2004Est. completion: Jul 20068 patients
Phase 4Completed

A Trial to Assess the Efficacy and Safety of SPM 927 (Lacosamide) in Subjects With Painful Distal Diabetic Neuropathy

Start: Dec 2003Est. completion: Jan 2005357 patients
Phase 3Completed

A Follow-On Trial to Assess the Long Term Safety and Efficacy of SPM 927 in Painful Distal Diabetic Neuropathy

Start: Sep 2004Est. completion: Jul 2008451 patients
Phase 2/3Completed

A Trial to Assess the Efficacy and Safety of SPM 927 in Subjects With Painful Distal Diabetic Neuropathy

Start: Apr 2004Est. completion: Jun 2005496 patients
Phase 2/3Completed

Study of DA-9801 to Treat Diabetic Neuropathy

Start: Nov 2013Est. completion: Jan 2015128 patients
Phase 2Completed

A Study of Effectiveness and Safety of JNJ-42160443 in Patients With Diabetic Painful Neuropathy

Start: Nov 2009Est. completion: Jun 201177 patients
Phase 2Terminated
NCT00608439Oregon TherapeuticsCentella asiatica selected triterpenes

Centella Asiatica Selected Triterpenes (CAST) for Diabetic Neuropathy

Start: Sep 2007Est. completion: Aug 201143 patients
Phase 2Completed
NCT01820715Dong-A ST600㎍ of DA-3030 Injection

A Study to Evaluate the Safety of DA-3030 and to Explore the Efficacy for Diabetic Neuropathic Pain

Start: Jun 201031 patients
Phase 1Completed

Clinical Trial of SB-509-0401 in Subjects With Diabetic Neuropathy

Start: Apr 2005Est. completion: Jan 200812 patients
Phase 1Completed
NCT02402361UNION therapeuticsUnderstanding Risk Factors and Determinants for Neuropathic Pain

Understanding Risk Factors and Determinants for Neuropathic Pain

Start: Apr 2016Est. completion: Mar 2021200 patients
N/ACompleted

Related Jobs in Neurology

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

11 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.