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HIV-1-infection

Infectious Diseases
91
Pipeline Programs
30
Companies
50
Clinical Trials
9 recruiting
1
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
26
10
10
7
16
22
Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

Small Molecule
1579%
RNA Therapeutic
211%
Vaccine
211%
+ 177 programs with unclassified modality

Infectious Diseases is an $11.9B market dominated by HIV and hepatitis C treatments in their peak revenue phases, reflecting a mature but stable therapeutic area.

$11.9B marketMature→ Stable30 products15 companies

Key Trends

  • HIV antiretroviral dominance: Nucleoside Reverse Transcriptase Inhibitors account for 44% of spending
  • Patent cliff pressure: $2.8B in revenue from major products facing LOE between 2027–2031
  • High trial velocity: 9,337 active trials indicate sustained pipeline development despite market maturity

Career Verdict

Infectious Diseases offers stable, well-compensated roles with strong commercial demand, but limited growth upside—ideal for risk-averse professionals seeking established franchises rather than high-growth opportunities.

AI-generated market analysis based on FDA, CMS, ClinicalTrials.gov, and hiring data

Market Leaders

#1BIKTARVYStable
$3.2B
Gilead Sciences·Peak10.5yr
#2EPCLUSAStable
$877M
Gilead Sciences·Peak8.2yr
#3TIVICAYDeclining
$657M
GSK·Peak4.1yr
#4TRIUMEQDeclining
$632M
GSK·Peak4.1yr
#5GENVOYAStable
$626M
Gilead Sciences·Peak6.9yr

Drug Class Breakdown

Nucleoside Reverse Transcriptase Inhibitors
$5.2B(44%)

backbone of HIV treatment, stable demand

RNA Replicase Inhibitors
$1.8B(15%)

hepatitis C treatment, mature market

Cytochrome P450 3A Inhibitors
$1.4B(12%)

boosting agents in combination regimens

P-Glycoprotein Inhibitors
$343M(3%)

niche mechanism, limited growth

Career Outlook

Stable

Infectious Diseases offers predictable career progression and above-average compensation in Commercial roles, supported by 780 current openings and sustained demand from market incumbents. However, patent cliffs affecting $2.8B in near-term revenue (2027–2031) will compress margins and slow hiring after 2028, particularly in Commercial support and field-based roles. The area is best suited for mid-career professionals seeking stability over rapid growth, with limited appeal for early-career scientists pursuing innovation-driven research.

Breaking In

Enter via Commercial or Manufacturing roles at GSK, Sanofi, or Becton Dickinson to build market expertise and commanding salaries ($160K–$237K); avoid pure R&D tracks unless you target specific mechanisms like long-acting injectables.

For Experienced Professionals

Experienced professionals should pursue Market Access, Medical Affairs, or Commercial Leadership roles where patent cliff expertise commands premium compensation; consider consulting or biotech transition if R&D innovation is your priority.

In-Demand Skills

Market access and payer strategyBrand management in generic-transition environmentsManufacturing scale-up and supply chain optimizationMedical science liaison (MSL) capabilities for physician engagementHealth economics and real-world outcomes analysis

Best For

Brand ManagerMarket Access ManagerMedical Science LiaisonSales DirectorManufacturing EngineerHealth Economics Analyst

Hiring Landscape

$160K–$275K

Infectious Diseases hiring is heavily weighted toward Commercial roles (247 positions, 32% of total), reflecting mature market dynamics focused on market access and brand management. GSK and Becton Dickinson lead hiring (214 and 188 roles), but Gilead Sciences—the market leader by revenue—shows surprisingly low hiring (25 roles), signaling efficiency-driven operations. Salary progression favors Commercial ($275K avg) over R&D ($184K avg), indicating career acceleration through sales and marketing functions.

780
Open Roles
5
Companies Hiring
4
Departments

Top Hiring Companies

214Growing
100Stable
61Stable
51Growing

By Department

Commercial(32%)
$275K
Engineering(16%)
$237K
Manufacturing(14%)
$160K
Research & Development(9%)
$184K

Strong Commercial hiring with premium salaries suggests Infectious Diseases is an excellent landing spot for brand, sales, and market access professionals, but limited R&D hiring indicates reduced innovation investment.

On Market (1)

Approved therapies currently available

GSK
SELZENTRYApproved
maraviroc
GSK
CCR5 Co-receptor Antagonist [EPC]oral2016
9M Part D

Competitive Landscape

34 companies ranked by most advanced pipeline stage

Kite Pharma
Kite PharmaCA - El Segundo
42 programs
5
1
6
5
6
11
B/F/TAFPhase 4
B/F/TAFPhase 4
B/F/TAFPhase 4
B/F/TAFPhase 4
B/F/TAFPhase 4
+37 more programs
Allergy Therapeutics
Allergy TherapeuticsUK - West Sussex
14 programs
3
3
1
EtonogestrelPhase 41 trial
CAB LA 600mgPhase 1/21 trial
Once daily CAB tablet + RPV tabletPhase 1/2
PENNVAX-GPPhase 1/2
3M-052-AF + AlumPhase 1
+9 more programs
Active Trials
NCT04517825Completed242Est. Jun 2021
NCT05584397Enrolling By Invitation40Est. Dec 2025
NCT01934504Terminated33Est. Feb 2015
+10 more trials
GSK
GSKLONDON, United Kingdom
14 programs
1
Genotypic Resistance TestN/A1 trial
Home visit delivery strategyN/A1 trial
REGISTER CREATIONN/A1 trial
none of intervention was givenN/A1 trial
abacavir, dolutegravir and lamivudine dispersible tabletsPHASE_11 trial
+9 more programs
Active Trials
NCT04448158Completed79Est. Jul 2021
NCT05096949Terminated1Est. Dec 2023
NCT04098315Recruiting300Est. Dec 2028
+11 more trials
ViiV Healthcare
ViiV HealthcareNC - Durham
14 programs
1
2
7
DOVATOPhase 4
DolutegravirPhase 4Small Molecule
Dolutegravir/Lamivudine as a single pillPhase 4
Dual versus triple therapy in treatment of HIV-1 infection.Phase 4
Fostemsavir 600 MG [Rukobia]Phase 4
+9 more programs
MSD
MSDIreland - Ballydine
8 programs
4
1
Doravirine / lamivudine/ Tenofovir Disoproxil Oral TabletPhase 41 trial
DelstrigoPhase 31 trial
Doravirine + tenofovir DF + lamivudinePhase 31 trial
ISL/LENPhase 31 trial
ISL/LENPhase 31 trial
+3 more programs
Active Trials
NCT04253119Completed536Est. Jun 2022
NCT03340077Completed200Est. Dec 2019
NCT05418790Unknown15Est. Sep 2023
+5 more trials
UNION therapeutics
UNION therapeuticsDenmark - Hellerup
3 programs
1
B/F/TAFPhase 4
Efavirenz 400mgN/A1 trial
Lamivudine and Dotiravir Sodium TabletsN/A1 trial
Active Trials
NCT04596488Completed25Est. Dec 2019
NCT05332470Unknown200Est. May 2025
Sharp Therapeutics
Sharp TherapeuticsPA - Pittsburgh
5 programs
3
DelstrigoPhase 3
ISL/LENPhase 3
ISL/LENPhase 3
Medicines Optimisation Review toolkitN/A
TASSO deviceN/A
TaiMed Biologics
1
1
1
ibalizumab-uiykPhase 31 trial
TMB-365/TMB-380Phase 1/21 trial
TMB-365Phase 11 trial
Active Trials
NCT04027387Completed24Est. Aug 2021
NCT05275998Completed51Est. Nov 2024
NCT03913195Completed43Est. Oct 2022
Viriom
ViriomMD - Rockville
9 programs
5
1
2
VM-1500Phase 2/31 trial
VM-1500A-LAIPhase 2/31 trial
VM-1500A-LAIPhase 1/21 trial
Elpida®Phase 11 trial
Elpida®Phase 11 trial
+4 more programs
Active Trials
NCT03706950Unknown2,000Est. Dec 2022
NCT03709355Completed56Est. Sep 2019
NCT03706898Completed36Est. Apr 2019
+6 more trials
Colorado Therapeutics
Colorado TherapeuticsCO - Louisville
3 programs
1
1
TesamorelinPhase 21 trial
Prevnar-13Phase 11 trial
DoravirineN/A1 trial
Active Trials
NCT04495348Completed18Est. Jun 2023
NCT03729778Active Not Recruiting100Est. Jan 2028
NCT06554717Recruiting100Est. Jun 2028
Eppendorf
2 programs
1
1
Vaccine and vedolizumabPhase 2Vaccine1 trial
GTU-MultiHIV B-clade vaccine + MVA HIV-B HIV vaccinePhase 1/2Vaccine1 trial
Active Trials
NCT02972450Terminated1Est. Jul 2019
NCT04120415Completed2Est. Jul 2023
AbbVie
AbbVieNORTH CHICAGO, IL
1 program
1
CVC 150 mgPhase 21 trial
Active Trials
NCT05630885Completed110Est. Jun 2024
Coordination Pharmaceuticals
1 program
1
Doravirine 100Mg Tab and Lamivudine 300 Mg TabPhase 21 trial
Active Trials
NCT06774872Recruiting408Est. Jun 2028
Human BioSciences
Human BioSciencesWV - Martinsburg
6 programs
3
1
Once daily CAB tablet + RPV tabletPhase 1/21 trial
3M-052-AF + AlumPhase 11 trial
426c.Mod.Core-C4b 30 mcgPhase 11 trial
DV700P-RNAPhase 11 trial
Graphical Informed ConsentN/A1 trial
+1 more programs
Active Trials
NCT04668443Completed12Est. Dec 2021
NCT04024488Active Not Recruiting256Est. Oct 2025
NCT06905275Suspended25Est. Jul 2027
+3 more trials
Angeles Therapeutics
1
PENNVAX-GPPhase 1/2
EPTN/A1 trial
HIVST and enhanced adherence biofeedbackN/A1 trial
Specimen Repository for HIV ImmunopathogenesisN/A1 trial
Three-month ART dispensingN/A1 trial
Active Trials
NCT04553211Completed555Est. Apr 2024
NCT04897737Completed106Est. May 2021
NCT03579381Completed9Est. Jan 2019
+1 more trials
Inovio Pharmaceuticals
1 program
1
PENNVAX-GPPhase 1/21 trial
Active Trials
NCT03606213Completed56Est. May 2021
Excision BioTherapeutics
Excision BioTherapeuticsCA - San Francisco
2 programs
2
EBT-101Phase 11 trial
EBT-101Phase 11 trial
Active Trials
NCT05143307Enrolling By Invitation9Est. Apr 2037
NCT05144386Completed6Est. Nov 2024
BioTherapeutics Inc
BioTherapeutics IncVA - Blacksburg
2 programs
2
EBT-101Phase 1
EBT-101Phase 1
MacroGenics
MacroGenicsMD - Rockville
1 program
1
MGD014Phase 1
United BioPharma
1
UB-421 SCPhase 11 trial
Active Trials
NCT04620291Unknown18Est. Dec 2025
Aurum Biosciences
Aurum BiosciencesUK - Glasgow
1 program
1
eOD-GT8 60mer mRNA VaccinePhase 1RNA Therapeutic1 trial
Active Trials
NCT05414786Unknown18Est. Jun 2023
Gilead Sciences
Gilead SciencesFOSTER CITY, CA
42 programs
B/F/TAFN/A1 trial
B/F/TAFN/A1 trial
B/F/TAFN/A
Bictegravir/Emtricitabine/Tenofovir Alafenamide 50 MG-200 MG-25 MG Oral Tablet [BIKTARVY]N/A1 trial
Bictegravir/Emtricitabine/Tenofovir Alafenamide 50 MG-200 MG-25 MG Oral Tablet [BIKTARVY]N/A
+37 more programs
Active Trials
NCT03580668Completed201Est. Jun 2024
NCT04009057Completed143Est. Mar 2022
NCT05064020Active Not Recruiting162Est. Dec 2024
+32 more trials
Merck & Co.
Merck & Co.RAHWAY, NJ
4 programs
Medicines Optimisation Review toolkitN/A
TASSO deviceN/A
DelstrigoPHASE_3
ISL/LENPHASE_3
CytoDyn
CytoDynVANCOUVER, WA
2 programs
PRO 140PHASE_2_31 trial
PRO 140 350PHASE_2_31 trial
Active Trials
NCT03902522Completed6Est. May 2020
NCT05271370Terminated56Est. Jul 2022
United Therapeutics
United TherapeuticsMD - Silver Spring
1 program
Assess Therapeutic Efficacy and Emergence of HIV Drug Resistance Following Initiation of TLDN/A
Relief Therapeutics
Relief TherapeuticsSwitzerland - Geneva
1 program
Assess Therapeutic Efficacy and Emergence of HIV Drug Resistance Following Initiation of TLDN/A1 trial
Active Trials
NCT04050449Completed1,339Est. Mar 2023
Mission Therapeutics
Mission TherapeuticsUK - Cambridge
1 program
Clinical management informed by HIV-1 genotypic resistance testingN/A1 trial
Active Trials
NCT04233242Completed286Est. Jul 2023
Avenue Therapeutics
Avenue TherapeuticsFL - Bay Harbor Islands
1 program
LeukapheresisN/A
Oregon Therapeutics
LeukapheresisN/A1 trial
Active Trials
NCT03426189Completed8Est. Oct 2018
Roche
RocheSTAVANGER NORWAY, Norway
1 program
SARS-CoV-2 (COVID-19) Antibody PrevalencE in an Adult London HIV CohortN/A1 trial
Active Trials
NCT05067400Completed615Est. Jun 2023

+4 more companies

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
2028
2029
2030
MSDDoravirine / lamivudine/ Tenofovir Disoproxil Oral Tablet
GSKDOVATO
Allergy TherapeuticsEtonogestrel
Gilead SciencesB/F/TAF
GSKFostemsavir 600 MG [Rukobia]
Gilead SciencesB/F/TAF
GSKDolutegravir/Lamivudine as a single pill
Gilead SciencesB/F/TAF
Gilead SciencesB/F/TAF
GSKIntervention Arm: dolutegravir/lamivudine
GSKDual versus triple therapy in treatment of HIV-1 infection.
GSKDolutegravir
Gilead SciencesBictegravir/emtricitabine/tenofovir alafenamide
Gilead SciencesB/F/TAF
Gilead SciencesB/F/TAF

Showing 15 of 50 trials with date data

Clinical Trials (50)

Total enrollment: 11,616 patients across 50 trials

NCT07357584MSDDoravirine / lamivudine/ Tenofovir Disoproxil Oral Tablet

Efficacy and Safety of Doravirine in the Rapid Initiation

Start: Jul 2026Est. completion: Jan 2028100 patients
Phase 4Not Yet Recruiting

Evaluation of Switch to Dolutegravir/Lamivudine (DTG/3TC) From Current Suppressive Antiretroviral Therapy in People Living With HIV (PLWH) Receiving Opioid Agonist Therapy (OAT)

Start: Sep 2024Est. completion: Oct 202740 patients
Phase 4Not Yet Recruiting

Pharmacokinetic Interactions of ENG Subdermal Implants with Long-Acting Cabotegravir (CAB-LA) and LA Rilpivirine (RPV-LA) (CARLA)

Start: Jan 2024Est. completion: Aug 20240
Phase 4Withdrawn

Study of B/F/TAF in Participants Switching From CAB + RPV to B/F/TAF for HIV-1 Infection (EMPOWER)

Start: Dec 2023Est. completion: Apr 202533 patients
Phase 4Completed
NCT05220358GSKFostemsavir 600 MG [Rukobia]

Changes in Immunologic Parameters Following the Addition of Fostemsavir in Virologically Suppressed Immunologic Non-responders Living With HIV-the RECOVER Study

Start: Jun 2022Est. completion: Feb 202625 patients
Phase 4Active Not Recruiting

BFTAF Elderly Switch Study

Start: Feb 2022Est. completion: Mar 2024520 patients
Phase 4Completed
NCT04884139GSKDolutegravir/Lamivudine as a single pill

DTG/3TC vs. BIC/FTC/TAF Maintenance Therapy in People Living With HIV:

Start: Jul 2021Est. completion: Mar 2025554 patients
Phase 4Completed

Biktarvy in Treatment-Naïve Late Presenters With HIV-1 Infection

Start: Jul 2021Est. completion: Dec 2023250 patients
Phase 4Unknown

Study to Assess Switching to B/F/TAF in Treatment Experienced People With HIV Who Are at Least 65 Years of Age

Start: Jul 2021Est. completion: Dec 202250 patients
Phase 4Unknown
NCT04880395GSKIntervention Arm: dolutegravir/lamivudine

Dolutegravir-Lamivudine for naïve HIV-Infected Patients With ≤200 CD4/mm3

Start: May 2021Est. completion: May 2024265 patients
Phase 4Completed
NCT04553081GSKDual versus triple therapy in treatment of HIV-1 infection.

2DR Versus 3DR in a Prospective Randomized Controlled Switch Trial

Start: May 2020Est. completion: Apr 2027134 patients
Phase 4Recruiting
NCT04229290GSKDolutegravir

Second-line Switch to Dolutegravir Study

Start: Feb 2020Est. completion: Sep 2021795 patients
Phase 4Completed
NCT03998176Gilead SciencesBictegravir/emtricitabine/tenofovir alafenamide

Bictegravir/Emtricitabine/Tenofovir Alafenamide (B/F/TAF) in HIV-1 Infected Patients With Active Illicit Substance usE

Start: Oct 2019Est. completion: Apr 202243 patients
Phase 4Completed

B/F/TAF Switch Study for HIV-HBV Coinfection

Start: Apr 2019Est. completion: May 202328 patients
Phase 4Completed

B/F/TAF vs Atripla Double-Blind Switch Study in HIV-1 Infected Adults

Start: Oct 2018Est. completion: Sep 202028 patients
Phase 4Terminated

Switch to Genvoya Followed by HCV Therapy With Epclusa Followed by Simplification of HIV Therapy With Biktarvy in Patients With HIV-HCV Co-Infected Subjects on Opioid Substitution Therapy

Start: Feb 2018Est. completion: Jun 202125 patients
Phase 4Unknown

The Role of Home Packs of HIV PEPSE in High Risk Individuals

Start: Jan 2018Est. completion: Mar 2021139 patients
Phase 4Completed
NCT06203132MSDDoravirine + tenofovir DF + lamivudine

DORAvirine Versus DOlutegravir Based Antiretroviral Regimens in Treatment-naïve People Living With HIV-1 Infection

Start: Jan 2025Est. completion: Nov 2027610 patients
Phase 3Recruiting

Study to Compare an Oral Weekly Islatravir/Lenacapavir Regimen With Bictegravir/Emtricitabine/Tenofovir Alafenamide in Virologically Suppressed People With HIV-1

Start: Oct 2024Est. completion: Aug 2030609 patients
Phase 3Active Not Recruiting

Study to Compare an Oral Weekly Islatravir/Lenacapavir Regimen With Standard of Care in Virologically Suppressed People With HIV-1

Start: Oct 2024Est. completion: Aug 2030600 patients
Phase 3Active Not Recruiting

B/F/TAF to DTG/3TC Switch Study

Start: Jul 2024Est. completion: Aug 2026240 patients
Phase 3Active Not Recruiting

Study to Compare Bictegravir/Lenacapavir Versus Current Therapy in People With HIV-1 Who Are Successfully Treated With Biktarvy

Start: Mar 2024Est. completion: Dec 2029577 patients
Phase 3Active Not Recruiting

A Randomised, Phase 3 Non-inferiority Study of DOR/3TC/TDF Compared to DTG/TAF/FTC in Participants Infected With HIV-1 Starting First-line Antiretroviral Therapy

Start: Nov 2023Est. completion: Jun 2026600 patients
Phase 3Active Not Recruiting

A Test and Treat Strategy in New HIV Diagnosis.

Start: Oct 2020Est. completion: May 2023100 patients
Phase 3Completed

Study of the Safety of Trogarzo™ Administered as an Undiluted "IV Push" or an Intramuscular Injection

Start: May 2019Est. completion: Oct 202243 patients
Phase 3Completed
NCT05349838GSKDolutegravir & Rilpivirine 2 drug fixed dose combined therapy

Open-Label Multi-Centre Randomised Switch Study to Evaluate Virological Efficacy Over 96Weeks Of 2-Drug Therapy With Dolutegravir(DTG)/Rilpivirine(RPV) Fixed Dose Combination(FDC) in Antiretroviral Treatment-Experienced HIV-1 Infected Subjects Virologically Suppressed With NNRTI Mutation K103N

Start: Nov 2018Est. completion: Nov 2022140 patients
Phase 3Completed

Switching to a Fixed Dose Combination of Bictegravir/Emtricitabine/Tenofovir Alafenamide (B/F/TAF) in Human Immunodeficiency Virus Type 1 (HIV-1) Infected Adults Who Are Virologically Suppressed

Start: Jun 2017Est. completion: Feb 2021567 patients
Phase 3Completed
NCT03493568Gilead SciencesGenvoya 150Mg-150Mg-200Mg-10Mg Tablet

Switch From Dual Regimens Based on Dolutegravir Plus a Reverse Transcriptase Inhibitor to E/C/F/TAF in Virologically Suppressed, HIV-1 Infected Patients (Be-OnE)

Start: Feb 2017Est. completion: Jul 2020100 patients
Phase 3Terminated

Study to Evaluate the Safety and Efficacy of Bictegravir/Emtricitabine/Tenofovir Alafenamide Versus Abacavir/Dolutegravir/Lamivudine in Human Immunodeficiency Virus-1 (HIV-1) Infected, Antiretroviral Treatment-Naive Adults

Start: Nov 2015Est. completion: Jul 2021631 patients
Phase 3Completed

Safety and Efficacy of Switching From Dolutegravir and ABC/3TC or ABC/DTG/3TC to B/F/TAF in HIV-1 Infected Adults Who Are Virologically Suppressed

Start: Nov 2015Est. completion: Oct 2019567 patients
Phase 3Completed

Study of Bictegravir/Lenacapavir in Children and Adolescents With HIV-1

Start: Nov 2024Est. completion: Aug 202875 patients
Phase 2/3Recruiting

Study of Oral Weekly Lepetegravir (Formerly GS-1720) and Lenacapavir Pacfosacil (Formerly GS-4182) Versus Biktarvy in People With HIV-1 Who Are Virologically Suppressed

Start: Aug 2024Est. completion: Jun 2029675 patients
Phase 2/3Active Not Recruiting

Study to Compare Bictegravir/Lenacapavir Versus Current Therapy in People With HIV-1 Who Are Successfully Treated With a Complicated Regimen

Start: Aug 2022Est. completion: Jul 2028689 patients
Phase 2/3Active Not Recruiting
NCT05204394ViriomVM-1500A-LAI

Study to Evaluate Efficacy and Safety of Switching to VM-1500A-LAI + 2NRTIs From the 1st Line Standard of Care Therapy

Start: Apr 2022Est. completion: Oct 2023438 patients
Phase 2/3Unknown

Study to Evaluate the Safety and Efficacy of Lenacapavir (GS-6207) in Combination With an Optimized Background Regimen (OBR) in Heavily Treatment Experienced Participants Living With HIV-1 Infection With Multidrug Resistance

Start: Nov 2019Est. completion: Jan 202772 patients
Phase 2/3Active Not Recruiting

PRO 140 in Treatment-Experienced HIV-1 Subjects

Start: Jun 2018Est. completion: May 20206 patients
Phase 2/3Completed

An Extension Protocol for Virologically Suppressed Subjects Who Successfully Completed PRO140_CD03 Study

Start: Aug 2017Est. completion: Jul 202256 patients
Phase 2/3Terminated

Efficacy, Safety and Optimal Dose of VM-1500 in Comparison to Efavirenz Added to Standard-of-care Antiretroviral Therapy

Start: Aug 2014Est. completion: Sep 2017150 patients
Phase 2/3Completed

Tesamorelin as an Adjunct to Exercise for Improving Physical Function in HIV

Start: Jul 2025Est. completion: Jun 2028100 patients
Phase 2Recruiting
NCT06774872Coordination PharmaceuticalsDoravirine 100Mg Tab and Lamivudine 300 Mg Tab

Doravirine/Lamivudine (DOR/3TC) as a Maintenance ART in Comparison With Dolutegravir/Lamivudine (DTG/3TC) in PLWH Successfully

Start: Apr 2025Est. completion: Jun 2028408 patients
Phase 2Recruiting

Evaluation of Long-Acting Lenacapavir for the Treatment of HIV-1 in Treatment-experienced Adolescents and Children

Start: Mar 2025Est. completion: Sep 202712 patients
Phase 2Recruiting
NCT06631365Gilead SciencesPrEPsmart mobile app

PrEPsmart 2-1-1 Pilot

Start: Oct 2023Est. completion: Apr 202560 patients
Phase 2Recruiting

A Study to Evaluate the Effects of Cenicriviroc Mesylate on Arterial Inflammation in People Living With HIV

Start: May 2023Est. completion: Jun 2024110 patients
Phase 2Completed
NCT04120415EppendorfVaccine and vedolizumab

A HIV Vaccine Trial in Individuals Who Started Antiretrovirals During Primary or Chronic Infection (EHVA T02)

Start: Jun 2022Est. completion: Jul 20232 patients
Phase 2Completed

Study of VRC07-523LS, CAP256V2LS, and Vesatolimod, in Early Antiretroviral-treated HIV-1 Clade C-infected Women

Start: Jun 2022Est. completion: Jan 202520 patients
Phase 2Completed

Study to Evaluate the Safety and Efficacy of Lenacapavir (GS-6207) in Combination With Other Antiretroviral Agents in People Living With HIV

Start: Nov 2019Est. completion: Sep 2023183 patients
Phase 2Completed

Study to Evaluate the Efficacy of GS-9131 Functional Monotherapy in Human Immunodeficiency Virus (HIV)-1-Infected Adults Failing a Nucleos(t)Ide Reverse Transcriptase Inhibitor-Containing Regimen With Nucleos(t)Ide Reverse Transcriptase Inhibitor Resistant Virus

Start: Apr 2018Est. completion: Dec 201921 patients
Phase 2Terminated

CREATE - Cabotegravir & Rilpivirine Antiretroviral Therapy in Pregnancy

Start: May 2025Est. completion: Jan 20280
Phase 1/2Withdrawn
NCT06071767Gilead SciencesChAdOx1.tHIVconsv1

Evaluation of Safety, Immunogenicity and Efficacy of a Triple Immune Regimen in Adults Initiated on ART During Acute HIV-1

Start: Apr 2024Est. completion: Aug 202936 patients
Phase 1/2Recruiting
NCT05660980Human BioSciencesOnce daily CAB tablet + RPV tablet

Study of Oral and Long-Acting Injectable Cabotegravir and Rilpivirine in Virologically Suppressed Children Living With HIV-1, Two to Less Than 12 Years of Age

Start: Jan 2024Est. completion: Aug 202790 patients
Phase 1/2Recruiting

Related Jobs in Infectious Diseases

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

16 late-stage (Phase 3) programs, potential near-term approvals
9 actively recruiting trials targeting 11,616 patients
30 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.