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Intracranial Aneurysms

2
Pipeline Programs
8
Companies
9
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
1
0
0
0
0
1
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

4 companies ranked by most advanced pipeline stage

Stryker
StrykerCA - San Jose
4 programs
1
Matrix 2® coils for endovascular aneurysm occlusionPhase 41 trial
Target 360°, 2D Coils, Nano CoilsN/A1 trial
TransForm™ Occlusion Balloon CatheterN/A1 trial
Ultra Coils From Start to Finish for the Endovascular Repair of Small Intracranial AneurysmsN/A1 trial
Active Trials
NCT01748903Unknown150Est. Mar 2019
NCT01949779Completed81Est. Jan 2015
NCT02657772Completed100Est. Mar 2021
+1 more trials
Evasc Medical Systems
Evasc Medical SystemsBC - Vancouver
1 program
1
eCLIPs™ Family of ProductsPhase 11 trial
Active Trials
NCT01957683Withdrawn0Est. Jan 2022
Penumbra
PenumbraALAMEDA, CA
3 programs
PC 400N/A1 trial
PC 400 coilsN/A1 trial
PC 400 coilsN/A1 trial
Active Trials
NCT02122133Terminated67Est. Oct 2016
NCT01465841Completed517Est. Jun 2017
NCT01754051Completed100Est. Oct 2017
Medtronic
MedtronicNJ - Phillipsburg
1 program
Barrel™ Vascular Reconstruction DeviceN/A1 trial
Active Trials
NCT02125097Completed20Est. Dec 2015

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
StrykerMatrix 2® coils for endovascular aneurysm occlusion
Evasc Medical SystemseCLIPs™ Family of Products
PenumbraPC 400
MedtronicBarrel™ Vascular Reconstruction Device
StrykerTransForm™ Occlusion Balloon Catheter
StrykerUltra Coils From Start to Finish for the Endovascular Repair of Small Intracranial Aneurysms
StrykerTarget 360°, 2D Coils, Nano Coils
PenumbraPC 400 coils
PenumbraPC 400 coils

Clinical Trials (9)

Total enrollment: 1,661 patients across 9 trials

NCT00396981StrykerMatrix 2® coils for endovascular aneurysm occlusion

MAPS Trial: Matrix And Platinum Science

Start: Mar 2007Est. completion: Mar 2015626 patients
Phase 4Completed
NCT01957683Evasc Medical SystemseCLIPs™ Family of Products

Canadian eCLIPs™ Safety and Feasibility Study Protocol

Start: Jan 2020Est. completion: Jan 20220
Phase 1Withdrawn
NCT02122133PenumbraPC 400

CARE: A Prospective Multicenter Case Study to Assess Radiation Exposure in Patients Treated With the Penumbra Coil 400

Start: May 2015Est. completion: Oct 201667 patients
N/ATerminated
NCT02125097MedtronicBarrel™ Vascular Reconstruction Device

The Reverse Barrel™ VRD Intracranial Aneurysm Trial

Start: Dec 2013Est. completion: Dec 201520 patients
N/ACompleted
NCT01949779StrykerTransForm™ Occlusion Balloon Catheter

TransForm™ Occlusion Balloon Catheter Registry

Start: Dec 2013Est. completion: Jan 201581 patients
N/ACompleted
NCT02657772StrykerUltra Coils From Start to Finish for the Endovascular Repair of Small Intracranial Aneurysms

Ultra Coils From Start to Finish for the Endovascular Repair of Small Intracranial Aneurysms

Start: Nov 2013Est. completion: Mar 2021100 patients
N/ACompleted
NCT01748903StrykerTarget 360°, 2D Coils, Nano Coils

TARGET Intracranial Aneurysm Coiling Registry

Start: Feb 2013Est. completion: Mar 2019150 patients
N/AUnknown
NCT01754051PenumbraPC 400 coils

A Volumetric Coiling in Aneurysm Registry of the Penumbra Coil 400TM System

Start: Jan 2013Est. completion: Oct 2017100 patients
N/ACompleted
NCT01465841PenumbraPC 400 coils

Study of the Penumbra Coil 400 System to Treat Aneurysm

Start: Nov 2011Est. completion: Jun 2017517 patients
N/ACompleted

Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

8 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.