Ventilator Associated Pneumonia

Infectious Diseases
4
Pipeline Programs
8
Companies
4
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
1
0
2
0
0
1
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

4 companies ranked by most advanced pipeline stage

M&
Merck & Co.RAHWAY, NJ
1 program
1
ImipenemPhase 41 trial
Active Trials
NCT01379157Completed8Est. Jul 2014
BioVersys
BioVersysSwitzerland - Basel
1 program
1
BV100 plus Polymyxin BPhase 21 trial
Active Trials
NCT05685615Completed39Est. Dec 2024
Nektar Therapeutics
Nektar TherapeuticsSAN FRANCISCO, CA
1 program
1
aerosolized vancomycin or gentamicinPhase 21 trial
Active Trials
NCT00396578CompletedEst. Sep 2004
BP
Basilea PharmaceuticaSwitzerland - Allschwil
1 program
1
CeftobiprolePhase 11 trial
Active Trials
NCT00771719TerminatedEst. Nov 2009

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
Merck & Co.Imipenem
BioVersysBV100 plus Polymyxin B
Nektar Therapeuticsaerosolized vancomycin or gentamicin
Basilea PharmaceuticaCeftobiprole

Clinical Trials (4)

Total enrollment: 47 patients across 4 trials

NCT01379157Merck & Co.Imipenem

Pharmacodynamics Study of Imipenem in Patients With Ventilator Associated Pneumonia

Start: Nov 2011Est. completion: Jul 20148 patients
Phase 4Completed
NCT05685615BioVersysBV100 plus Polymyxin B

PK of BV100 in Patients VABP Suspected or Confirmed to Be Due to CRAB

Start: Apr 2023Est. completion: Dec 202439 patients
Phase 2Completed
NCT00396578Nektar Therapeuticsaerosolized vancomycin or gentamicin

Aerosolized Antibiotics and Respiratory Tract Infection in Patients on Mechanical Ventilation

Start: Aug 2003Est. completion: Sep 2004
Phase 2Completed
NCT00771719Basilea PharmaceuticaCeftobiprole

Open Label Pharmacokinetic in Adult Patients With Ventilator-Associated Pneumonia

Start: Oct 2008Est. completion: Nov 2009
Phase 1Terminated

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Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

8 companies competing in this space

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