EPCLUSA

Peak

velpatasvir and sofosbuvir

NDAORALTABLETPriority Review
Approved
Jun 2016
Lifecycle
Peak
Competitive Pressure
0/100
Clinical Trials
2

Mechanism of Action

Breast Cancer Resistance Protein Inhibitors

Pharmacologic Class:

Hepatitis C Virus NS5A Inhibitor

Clinical Trials (2)

NCT03549312Phase 4Unknown

Switch to Genvoya Followed by HCV Therapy With Epclusa Followed by Simplification of HIV Therapy With Biktarvy in Patients With HIV-HCV Co-Infected Subjects on Opioid Substitution Therapy

Started Feb 2018
25 enrolled
HIV-1-infectionHepatitis C, ChronicMethadone Dependence+6 more
NCT02175758Phase 2Completed

Safety and Efficacy of Sofosbuvir + Ribavirin in Adolescents and Children With Genotype 2 or 3 Chronic HCV Infection

Started Jul 2014
106 enrolled
Hepatitis C Virus Infection

Loss of Exclusivity

LOE Date
Jul 30, 2034
102 months away
Patent Expiry
Jul 30, 2034
Exclusivity Expiry
Sep 19, 2027

Patent Records (5)

Patent #ExpiryTypeUse Code
8580765
Mar 21, 2028
SubstanceProduct
U-1470
9085573
Mar 21, 2028
SubstanceProduct
U-1470
8334270
Mar 21, 2028
SubstanceProduct
U-1470
8735372
Mar 21, 2028
U-1470
8334270*PED
Sep 21, 2028