Unresectable Metastatic Colorectal Cancer

Oncology
3
Pipeline Programs
3
Companies
3
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
2
0
1
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

3 companies ranked by most advanced pipeline stage

AB
AP BiosciencesTaiwan - Taipei
1 program
1
Avastin, 25 Mg/mL Intravenous SolutionPhase 31 trial
Active Trials
NCT06642844Not Yet RecruitingEst. Oct 2029
AbbVie
AbbVieNORTH CHICAGO, IL
1 program
1
ABBV-400Phase 21 trial
Active Trials
NCT06107413Active Not Recruiting280Est. Dec 2026
CT
1 program
1
AK105 injectionPhase 21 trial
Active Trials
NCT05068206UnknownEst. Jun 2024

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
2028
2029
AP BiosciencesAvastin, 25 Mg/mL Intravenous Solution
AbbVieABBV-400
Chia Tai TianQing Pharmaceutical GroupAK105 injection

Clinical Trials (3)

Total enrollment: 280 patients across 3 trials

NCT06642844AP BiosciencesAvastin, 25 Mg/mL Intravenous Solution

Bevacizumab-based Chemotherapy Adapted to Bevacizumab Pharmacokinetics in 1st-line Treatment

Start: Oct 2024Est. completion: Oct 2029
Phase 3Not Yet Recruiting
NCT06107413AbbVieABBV-400

Study to Assess Adverse Events and Change in Disease Activity in Previously Treated Adult Participants Receiving Intravenous (IV) ABBV-400 With Unresectable Metastatic Colorectal Cancer in Combination With IV Fluorouracil, Folinic Acid, and Bevacizumab

Start: Nov 2023Est. completion: Dec 2026280 patients
Phase 2Active Not Recruiting
NCT05068206Chia Tai TianQing Pharmaceutical GroupAK105 injection

A Clinical Study to Compare the Efficacy and Safety of AK105 Plus Anlotinib and Capecitabine/Oxaliplatin (CapeOx) , Anlotinib Plus CapeOx, Bevacizumab Plus CapeOx

Start: Oct 2021Est. completion: Jun 2024
Phase 2Unknown

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Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

1 late-stage (Phase 3) programs — potential near-term approvals
3 companies competing in this space

Related Indications

Breast Cancer(530)Non-small Cell Lung Cancer(373)Prostate Cancer(371)Multiple Myeloma(244)Advanced Solid Tumors(221)Acute Myeloid Leukemia(204)Cancer(187)Neoplasms(173)Colorectal Cancer(166)Advanced Solid Tumor(165)