Spinal Muscular Atrophy (SMA)

Rare Diseases
1
Pipeline Programs
3
Companies
3
Clinical Trials
2 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
1
0
0
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

2 companies ranked by most advanced pipeline stage

argenx
argenxBelgium - Zwijnaarde
1 program
1
ARGX-119 IVPhase 21 trial
Active Trials
NCT07287982Recruiting60Est. May 2029
Biogen
BiogenCAMBRIDGE, MA
2 programs
RisdiplamN/A1 trial
Virtual realityN/A1 trial
Active Trials
NCT06978985Recruiting600Est. Apr 2027
NCT05354414Completed63Est. Jul 2024

Trial Timeline

Clinical trial activity over time

2022
2023
2024
2025
2026
2027
2028
2029
argenxARGX-119 IV
BiogenRisdiplam
BiogenVirtual reality

Clinical Trials (3)

Total enrollment: 723 patients across 3 trials

A Study to Assess the Safety, Tolerability, Efficacy, Pharmacokinetics, and Immunogenicity of Intravenous Administration of ARGX-119 in Pediatric Participants Aged 5 to Less Than 18 Years With Spinal Muscular Atrophy

Start: Dec 2025Est. completion: May 202960 patients
Phase 2Recruiting

Adult SMA Research and Clinical Hub

Start: Jul 2022Est. completion: Apr 2027600 patients
N/ARecruiting
NCT05354414BiogenVirtual reality

Virtual Reality for the Mitigation of Anxiety During Intrathecal Administration in Participants With Spinal Muscular Atrophy

Start: May 2022Est. completion: Jul 202463 patients
N/ACompleted

Related Jobs in Rare Diseases

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

2 actively recruiting trials targeting 723 patients
3 companies competing in this space