BLAINJECTIONSOLUTIONPriority Review
Approved
Oct 2015
Lifecycle
Peak
Competitive Pressure
30/100
Clinical Trials
18
Data completeness
3/8 — Basic
Priority Review
Drug data last refreshed 12h ago · AI intelligence enriched 1mo ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
STRENSIQ (asfotase alfa) is a recombinant tissue-nonspecific alkaline phosphatase (TNSALP) enzyme replacement therapy administered by injection. It treats hypophosphatasia, a rare genetic disorder characterized by deficient alkaline phosphatase activity leading to impaired bone mineralization and soft tissue calcification. The drug works by providing exogenous alkaline phosphatase enzyme to normalize mineral metabolism and improve skeletal outcomes.
$259MPart D
PeakStable
Peak lifecycle status indicates mature commercial infrastructure with established market penetration; team is likely stable with focus on market maintenance and line extension rather than rapid growth.
Mechanism of Action
Pharmacologic Class:
Tissue-nonspecific Alkaline Phosphatase
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (18)
Mitigate Immune-Mediated Loss of Therapeutic Response to Asfotase Alfa (STRENSIQ®) for Hypophosphatasia
Started Jul 2026
0Hypophosphatasia
Phase 3 Study of ALXN1850 in Pediatric Participants With HPP Previously Treated With Asfotase Alfa
Started Apr 2024
43 enrolled
Hypophosphatasia
Phase 3 Study of ALXN1850 Versus Placebo in Adolescent and Adult Participants With HPP Who Have Not Previously Been Treated With Asfotase Alfa
Started Jan 2024
124 enrolled
Hypophosphatasia
A Prospective Sub-Study of the Global Hypophosphatasia Registry
Started Aug 2022
30 enrolled
Hypophosphatasia
Relieving Burden of Hypophosphatasia in Adults With Functional Impairment Due to Chronic Disease
Started Apr 2020
0Hypophosphatasia
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.