Preterm Delivery

Gastroenterology
6
Pipeline Programs
3
Companies
3
Clinical Trials
3
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
2
0
1
3
Early DiscoveryClinical DevelopmentMarket

On Market (3)

Approved therapies currently available

U
PROGESTASERTApproved
progesterone
Unknown Company
intrauterine1976
U
PROGESTERONEApproved
progesterone
Unknown Company
Progesterone [EPC]oral2017
U
PROMETRIUMApproved
progesterone
Unknown Company
oral1998

Competitive Landscape

3 companies ranked by most advanced pipeline stage

T-Therapeutics
T-TherapeuticsUK - Cambridge
1 program
1
progesteronePhase 31 trial
Active Trials
NCT00536003TerminatedEst. Dec 2012
Ferring Pharmaceuticals
Ferring PharmaceuticalsArgentina - Buenos Aires
1 program
1
MerotocinPhase 21 trial
Active Trials
NCT02545127Terminated4Est. Nov 2022
AB
AP BiosciencesTaiwan - Taipei
1 program
1
ProgesteronePhase 21 trial
Active Trials
NCT00329914CompletedEst. Sep 2010

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
T-Therapeuticsprogesterone
Ferring PharmaceuticalsMerotocin
AP BiosciencesProgesterone

Clinical Trials (3)

Total enrollment: 4 patients across 3 trials

NCT00536003T-Therapeuticsprogesterone

Vaginal Progesterone to Prevent Preterm Delivery in Women With Preterm Labor

Start: Jul 2006Est. completion: Dec 2012
Phase 3Terminated
NCT02545127Ferring PharmaceuticalsMerotocin

Merotocin in Mothers With Inadequate Milk Production and Infants Delivered Prematurely

Start: May 2021Est. completion: Nov 20224 patients
Phase 2Terminated
NCT00329914AP BiosciencesProgesterone

Does Progesterone Prevent Very Preterm Delivery in Twin Pregnancies?

Start: Jun 2006Est. completion: Sep 2010
Phase 2Completed

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Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

1 late-stage (Phase 3) programs — potential near-term approvals
3 companies competing in this space

Related Indications

Hepatic Impairment(79)Gastroesophageal Reflux Disease(37)Irritable Bowel Syndrome(29)Gastroesophageal Reflux(27)Liver Transplantation(24)Celiac Disease(23)Hepatic Insufficiency(22)Liver Cirrhosis(22)Gastroesophageal Reflux Disease (GERD)(14)Hepatic Encephalopathy(12)