Non-Squamous Cell Non-small Cell Lung Cancer

Oncology
4
Pipeline Programs
2
Companies
3
Clinical Trials
1
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
1
0
1
0
1
1
Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

Monoclonal Antibody
1100%
+ 2 programs with unclassified modality

On Market (1)

Approved therapies currently available

Bristol Myers Squibb
OPDIVOApproved
nivolumab
Bristol Myers Squibb
injection2015

Competitive Landscape

2 companies ranked by most advanced pipeline stage

Bristol Myers Squibb
1 program
1
1
NivolumabPhase 3Monoclonal Antibody1 trial
Active Trials
NCT01673867Completed582Est. Dec 2021
CT
2 programs
1
1
Anlotinib plus PemetrexedPhase 21 trial
Anlotinib Combined With Pemetrexed And CarboplatinPhase 11 trial
Active Trials
NCT03790228UnknownEst. Aug 2021
NCT03778138UnknownEst. Dec 2020

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
Bristol Myers SquibbNivolumab
Chia Tai TianQing Pharmaceutical GroupAnlotinib plus Pemetrexed
Chia Tai TianQing Pharmaceutical GroupAnlotinib Combined With Pemetrexed And Carboplatin

Clinical Trials (3)

Total enrollment: 582 patients across 3 trials

NCT01673867Bristol Myers SquibbNivolumab

Study of BMS-936558 (Nivolumab) Compared to Docetaxel in Previously Treated Metastatic Non-squamous NSCLC

Start: Nov 2012Est. completion: Dec 2021582 patients
Phase 3Completed
NCT03778138Chia Tai TianQing Pharmaceutical GroupAnlotinib plus Pemetrexed

Study of Anlotinib Combined With Pemetrexed in Patients With Advanced Nonsquamous NSCLC

Start: Jan 2019Est. completion: Dec 2020
Phase 2Unknown
NCT03790228Chia Tai TianQing Pharmaceutical GroupAnlotinib Combined With Pemetrexed And Carboplatin

Anlotinib Combined With Pemetrexed And Carboplatin as First-line Treatment in Advanced Nonsquamous NSCLC

Start: Mar 2019Est. completion: Aug 2021
Phase 1Unknown

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Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

1 late-stage (Phase 3) programs — potential near-term approvals
2 companies competing in this space

Related Indications

Breast Cancer(530)Non-small Cell Lung Cancer(373)Prostate Cancer(371)Multiple Myeloma(244)Advanced Solid Tumors(221)Acute Myeloid Leukemia(204)Cancer(187)Neoplasms(173)Colorectal Cancer(166)Advanced Solid Tumor(165)